Activated Ras Signaling Pathways and Reovirus Oncolysis: An Update on the Mechanism of Preferential Reovirus Replication in Cancer Cells

The Interplay of Reovirus with Autophagy

(2014) Hung-Chuan Chiu et al.   Biomed Research International

Reovirus modulates autophagy during oncolysis of multiple myeloma

(2013) Chandini M. Thirukkumaran et al.   Autophagy

Daxx Upregulation within the Cytoplasm of Reovirus-Infected Cells Is Mediated by Interferon and Contributes to Apoptosis

(2013) K. R. Dionne et al.   JOURNAL OF VIROLOGY

Reovirus Cell Entry Requires Functional Microtubules

(2013) B. A. Mainou et al.   mBio

Reovirus Activates a Caspase-Independent Cell Death Pathway

(2013) A. K. Berger et al.   mBio

Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus production

(2012) Songshu Meng et al.   ARCHIVES OF VIROLOGY

Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

(2012) Katie Twigger et al.   BMC CANCER

Reovirus as a Viable Therapeutic Option for the Treatment of Multiple Myeloma

(2012) C. M. Thirukkumaran et al.   CLINICAL CANCER RESEARCH

Cell Entry-Associated Conformational Changes in Reovirus Particles Are Controlled by Host Protease Activity

(2012) J. A. Madren et al.   JOURNAL OF VIROLOGY

Transport to Late Endosomes Is Required for Efficient Reovirus Infection

(2012) Bernardo A. Mainou et al.   JOURNAL OF VIROLOGY

Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples

(2012) Gerard J Nuovo et al.   MODERN PATHOLOGY

The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus

(2012) Kerstin Reiss et al.   PLoS Pathogens

Stabilisation of p53 enhances reovirus-induced apoptosis and virus spread through p53-dependent NF-κB activation

(2011) D Pan et al.   BRITISH JOURNAL OF CANCER

Necroptosis: An emerging form of programmed cell death

(2011) Wei Wu et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Apoptosis Induced by Mammalian Reovirus Is Beta Interferon (IFN) Independent and Enhanced by IFN Regulatory Factor 3- and NF- B-Dependent Expression of Noxa

(2011) J. J. Knowlton et al.   JOURNAL OF VIROLOGY

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction and augments bortezomib-mediated apoptosis in multiple myeloma

(2011) K R Kelly et al.   ONCOGENE

Crystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated Oligosaccharides

(2011) Dirk M. Reiter et al.   PLoS Pathogens

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Oncogenic Ras Promotes Reovirus Spread by Suppressing IFN-β Production through Negative Regulation ofRIG-ISignaling

(2010) Maya Shmulevitz et al.   CANCER RESEARCH

Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics

(2010) K.J. Harrington et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Alternative cell death mechanisms in development and beyond

(2010) J. Yuan et al.   GENES & DEVELOPMENT

Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation

(2010) Chung   INTERNATIONAL JOURNAL OF ONCOLOGY

Reovirus Infection or Ectopic Expression of Outer Capsid Protein  1 Induces Apoptosis Independently of the Cellular Proapoptotic Proteins Bax and Bak

(2010) M. L. Wisniewski et al.   JOURNAL OF VIROLOGY

The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis

(2010) Lucy Heinemann et al.   MOLECULAR THERAPY

Bid Regulates the Pathogenesis of Neurotropic Reovirus

(2010) Pranav Danthi et al.   PLoS Pathogens

Reovirus-based therapy for cancer

(2009) Kevin Kelly et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Fas-Mediated Apoptotic Signaling in the Mouse Brain following Reovirus Infection

(2009) P. Clarke et al.   JOURNAL OF VIROLOGY

Reovirus nonstructural protein  1s is required for establishment of viremia and systemic dissemination

(2009) K. W. Boehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reovirus infection of cancer cells is not due to activated Ras pathway

(2008) L Song et al.   CANCER GENE THERAPY

Reovirus: Viral Therapy for Cancer ‘as Nature Intended’

(2008) C. Comins et al.   CLINICAL ONCOLOGY

Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

(2008) F Errington et al.   GENE THERAPY