Revisiting PD-1 to target leukaemic stem cells

PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia

(2023) Xi Xu et al.   NATURE CELL BIOLOGY

Targeting PD-1/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia

(2022) Xingcheng Yang et al.   Experimental Hematology & Oncology

PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition

(2021) Kaitao Li et al.   Nature Communications

PD-1 and PD-L1 inhibitors foster the progression of adult T-cell Leukemia/Lymphoma

(2021) Mohammad Jalili-Nik et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Expression and significance of CD47, PD1 and PDL1 in T-cell acute lymphoblastic lymphoma/leukemia

(2018) Kun Yang et al.   PATHOLOGY RESEARCH AND PRACTICE

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome

(2017) Hashem O. Alsaab et al.   Frontiers in Pharmacology

Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia

(2017) Shi Hao Tan et al.   Frontiers in Oncology

Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

(2016) Keisuke Kataoka et al.   NATURE

Aldehyde dehydrogenases inhibition eradicates leukemia stem cells while sparing normal progenitors

(2016) G Venton et al.   Blood Cancer Journal

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

PD-1 targeting in cancer immunotherapy

(2012) Robert Ferris   CANCER