Inhibition of NF-kB/IL-6/JAK2/STAT3 Pathway and Epithelial-Mesenchymal Transition in Breast Cancer Cells by Azilsartan

Vincamine Modulates the Effect of Pantoprazole in Renal Ischemia/Reperfusion Injury by Attenuating MAPK and Apoptosis Signaling Pathways

(2022) Michael A. Fawzy et al.   MOLECULES

The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters

(2022) Iart Luca Shytaj et al.   mBio

Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential

(2022) Moustafa Fathy et al.   Nutrients

Gastroprotective Effect of Azilsartan Through Ameliorating Oxidative Stress, Inflammation, and Restoring Hydroxyproline, and Gastrin Levels in Ethanol-Induced Gastric Ulcer

(2022) Renas Raouf Hama Amin et al.   Journal of Inflammation Research

Kinetin Ameliorates Cisplatin-Induced Hepatotoxicity and Lymphotoxicity via Attenuating Oxidative Damage, Cell Apoptosis and Inflammation in Rats

(2022) Moustafa Fathy et al.   Biomedicines

Russelioside A, a Pregnane Glycoside from <i>Caralluma tuberculate</i>, Inhibits Cell-Intrinsic NF-κB Activity and Metastatic Ability of Breast Cancer Cells

(2022) Rahma Tharwat Sabra et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Nephroprotective potential of eugenol in a rat experimental model of chronic kidney injury; targeting NOX, TGF-β, and Akt signaling

(2022) Moustafa Fathy et al.   LIFE SCIENCES

Modulatory and Toxicological Perspectives on the Effects of the Small Molecule Kinetin

(2021) Eman M. Othman et al.   MOLECULES

Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells

(2021) RANIA ALAAELDIN et al.   ANTICANCER RESEARCH

Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus

(2021) Amira A. Abdellatef et al.   Journal of Natural Medicines

A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?

(2021) Nardeen Eldafashi et al.   Cancers

In vitro inhibition and molecular docking of a new ciprofloxacin‐chalcone against SARS‐CoV‐2 main protease

(2021) Rania Alaaeldin et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Pantoprazole Attenuates MAPK (ERK1/2, JNK, p38)–NF-κB and Apoptosis Signaling Pathways after Renal Ischemia/Reperfusion Injury in Rats

(2021) Michael A. Fawzy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway

(2021) Rania Alaaeldin et al.   MOLECULES

AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats

(2020) Moustafa Fathy et al.   MOLECULES

Cell Cycle Arrest and Apoptotic Effect of 7-(4-(N-substituted carbamoylmethyl) piperazin-1-yl) Ciprofloxacin-derivative on HCT 116 and A549 Cancer Cells

(2020) RANIA ALAAELDIN et al.   ANTICANCER RESEARCH

Preconditioning of Adipose-Derived Mesenchymal Stem-Like Cells with Eugenol Potentiates Their Migration and Proliferation In Vitro and Therapeutic Abilities in Rat Hepatic Fibrosis

(2020) Moustafa Fathy et al.   MOLECULES

Integrated structural and functional analysis of the protective effects of kinetin against oxidative stress in mammalian cellular systems

(2020) Muhammad Naseem et al.   Scientific Reports

A New Ciprofloxacin-derivative Inhibits Proliferation and Suppresses the Migration Ability of HeLa Cells

(2020) MOUSTAFA FATHY et al.   ANTICANCER RESEARCH

The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony-Forming Efficiency, and the Limbal Stem Cell Phenotype

(2019) Sai Kolli et al.   STEM CELLS

Immunotherapy and targeted therapy combinations in metastatic breast cancer

(2019) Francisco J Esteva et al.   LANCET ONCOLOGY

Downregulation of DPF3 promotes the proliferation and motility of breast cancer cells through activating JAK2/STAT3 signaling

(2019) Wei-hao Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation

(2019) Moustafa Fathy et al.   MOLECULES

Novel angiotensin receptor blocker, azilsartan induces oxidative stress and NFkB-mediated apoptosis in hepatocellular carcinoma cell line HepG2

(2018) Elham Ahmadian et al.   BIOMEDICINE & PHARMACOTHERAPY

Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin

(2018) Valeria R. Martínez et al.   TOXICOLOGY IN VITRO

In vivo attenuation of angiogenesis in hepatocellular carcinoma by Nigella sativa

(2018) Moustafa FATHY et al.   Turkish Journal Of Medical Sciences

Chlorogenic acid inhibits osteosarcoma carcinogenesis via suppressing the STAT3/Snail pathway

(2018) Fang Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Modulation of inducible nitric oxide synthase pathway by eugenol and telmisartan in carbon tetrachloride-induced liver injury in rats

(2018) Moustafa Fathy et al.   LIFE SCIENCES

Comparison of long-term safety of fixed-dose combinations azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide

(2017) Joel M. Neutel et al.   Journal of Clinical Hypertension

Functional proteomics outlines the complexity of breast cancer molecular subtypes

(2017) Angelo Gámez-Pozo et al.   Scientific Reports

TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts

(2016) Dominika Wolczyk et al.   CELLULAR ONCOLOGY

Simultaneous knockdown of uPA and MMP9 can reduce breast cancer progression by increasing cell-cell adhesion and modulating EMT genes

(2016) Anuradha Moirangthem et al.   Scientific Reports

Epithelial-Mesenchymal Transition and Breast Cancer

(2016) Yanyuan Wu et al.   Journal of Clinical Medicine

The relevance of EMT in breast cancer metastasis: Correlation or causality?

(2015) Ruben Bill et al.   FEBS LETTERS

The Role of Snail in EMT and Tumorigenesis

(2014) Yifan Wang et al.   CURRENT CANCER DRUG TARGETS

Cooperative actions of p21WAF1 and p53 induce Slug protein degradation and suppress cell invasion

(2014) J. Kim et al.   EMBO REPORTS

Tumor Dissemination: An EMT Affair

(2013) Jean Paul Thiery et al.   CANCER CELL

CD44 and SSEA-4 positive cells in an oral cancer cell line HSC-4 possess cancer stem-like cell characteristics

(2013) Zenko Noto et al.   ORAL ONCOLOGY

In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa

(2013) Moustafa Fathy et al.   Environmental Health and Preventive Medicine

Angiotensin II Facilitates Breast Cancer Cell Migration and Metastasis

(2012) Sylvie Rodrigues-Ferreira et al.   PLoS One

Azilsartan

(2011) Sum Lam   Cardiology in Review

Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: Role of NF-κB, Akt, ROS and MAP kinase pathway

(2008) Anita Goel et al.   CHEMICO-BIOLOGICAL INTERACTIONS

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT