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Title
KRAS
inhibitors: going noncovalent
Authors
Keywords
-
Journal
Molecular Oncology
Volume 16, Issue 22, Pages 3911-3915
Publisher
Wiley
Online
2022-11-16
DOI
10.1002/1878-0261.13341
References
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Related references
Note: Only part of the references are listed.- First data for sotorasib in patients with pancreatic cancer with KRAS p.G12C mutation: A phase I/II study evaluating efficacy and safety
- (2022) John H Strickler et al. JOURNAL OF CLINICAL ONCOLOGY
- KRYSTAL-1: Updated activity and safety of adagrasib (MRTX849) in patients (Pts) with unresectable or metastatic pancreatic cancer (PDAC) and other gastrointestinal (GI) tumors harboring a KRASG12C mutation.
- (2022) Tanios S. Bekaii-Saab et al. JOURNAL OF CLINICAL ONCOLOGY
- Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation
- (2022) Pasi A. Jänne et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor
- (2022) Jill Hallin et al. NATURE MEDICINE
- Sotorasib for Lung Cancers with KRAS p.G12C Mutation
- (2021) Ferdinandos Skoulidis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Acquired Resistance to KRASG12C Inhibition in Cancer
- (2021) Mark M. Awad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor
- (2021) Xiaolun Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- KRASG12C inhibition in colorectal cancer
- (2021) Per Pfeiffer et al. LANCET ONCOLOGY
- Targeting KRAS mutant lung cancer: light at the end of the tunnel
- (2021) Matthias Drosten et al. Molecular Oncology
- Diverse alterations associated with resistance to KRAS(G12C) inhibition
- (2021) Yulei Zhao et al. NATURE
- The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS
- (2021) Chuanchuan Li et al. SCIENCE
- Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer
- (2020) Pingping Hou et al. Cancer Discovery
- Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations
- (2015) J. C. Hunter et al. MOLECULAR CANCER RESEARCH
- Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer
- (2014) Avnish Kapoor et al. CELL
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
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