Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability
Authors
Keywords
-
Journal
MOLECULAR CELL
Volume 83, Issue 2, Pages 237-251.e7
Publisher
Elsevier BV
Online
2023-01-03
DOI
10.1016/j.molcel.2022.12.026
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
- (2022) Matthew Tegowski et al. MOLECULAR CELL
- Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
- (2022) Wenqi Xu et al. MOLECULAR CELL
- m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome
- (2022) Lulu Hu et al. NATURE BIOTECHNOLOGY
- Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI
- (2022) Cong Liu et al. NATURE BIOTECHNOLOGY
- m6A RNA methylation regulates the fate of endogenous retroviruses
- (2021) Tomasz Chelmicki et al. NATURE
- METTL3 regulates heterochromatin in mouse embryonic stem cells
- (2021) Wenqi Xu et al. NATURE
- The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
- (2021) Jiadong Liu et al. NATURE
- Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
- (2021) Eliza Yankova et al. NATURE
- Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos
- (2021) Chuan Chen et al. Protein & Cell
- Gene Architecture Facilitates Intron-Mediated Enhancement of Transcription
- (2021) Katherine Dwyer et al. Frontiers in Molecular Biosciences
- Acute depletion of METTL3 implicates N6-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome
- (2021) Guifeng Wei et al. GENOME RESEARCH
- Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution
- (2021) David Dierks et al. NATURE METHODS
- Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning
- (2021) Nadine Körtel et al. NUCLEIC ACIDS RESEARCH
- The Dynamics of Cytoplasmic mRNA Metabolism
- (2020) Timothy J. Eisen et al. MOLECULAR CELL
- N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
- (2020) Jun Liu et al. SCIENCE
- Limits in the detection of m6A changes using MeRIP/m6A-seq
- (2020) Alexa B. R. McIntyre et al. Scientific Reports
- Predicting mRNA Abundance Directly from Genomic Sequence Using Deep Convolutional Neural Networks
- (2020) Vikram Agarwal et al. Cell Reports
- A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA
- (2020) Sara Zaccara et al. CELL
- Gene Architecture and Sequence Composition Underpin Selective Dependency of Nuclear Export of Long RNAs on NXF1 and the TREX Complex
- (2020) Binyamin Zuckerman et al. MOLECULAR CELL
- WHISTLE: a high-accuracy map of the human N6-methyladenosine (m6A) epitranscriptome predicted using a machine learning approach
- (2019) Kunqi Chen et al. NUCLEIC ACIDS RESEARCH
- Regulation of transposable elements by DNA modifications
- (2019) Özgen Deniz et al. NATURE REVIEWS GENETICS
- Deciphering the “m6A Code” via Antibody-Independent Quantitative Profiling
- (2019) Miguel Angel Garcia-Campos et al. CELL
- m6A promotes R-loop formation to facilitate transcription termination
- (2019) Xin Yang et al. CELL RESEARCH
- Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues
- (2019) Jun’e Liu et al. MOLECULAR CELL
- N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
- (2019) Abdulkadir Abakir et al. NATURE GENETICS
- The dTAG system for immediate and target-specific protein degradation
- (2018) Behnam Nabet et al. Nature Chemical Biology
- Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency
- (2018) Annita Louloupi et al. Cell Reports
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- mRNP architecture in translating and stress conditions reveals an ordered pathway of mRNP compaction
- (2018) Anthony Khong et al. JOURNAL OF CELL BIOLOGY
- Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway
- (2018) Srivathsan Adivarahan et al. MOLECULAR CELL
- Higher-Order Organization Principles of Pre-translational mRNPs
- (2018) Mihir Metkar et al. MOLECULAR CELL
- Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
- (2018) Shinichiro Akichika et al. SCIENCE
- m 6 A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
- (2017) Shengdong Ke et al. GENES & DEVELOPMENT
- Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing
- (2016) Wen Xiao et al. MOLECULAR CELL
- m6A modulates neuronal functions and sex determination in Drosophila
- (2016) Tina Lence et al. NATURE
- Reversible methylation of m6Am in the 5′ cap controls mRNA stability
- (2016) Jan Mauer et al. NATURE
- YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
- (2016) Hao Du et al. Nature Communications
- The exon junction complex: a lifelong guardian of mRNA fate
- (2016) Lauren A. Woodward et al. Wiley Interdisciplinary Reviews-RNA
- Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution
- (2015) Yonatan Stelzer et al. CELL
- A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
- (2015) Shengdong Ke et al. GENES & DEVELOPMENT
- Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
- (2015) Bastian Linder et al. NATURE METHODS
- Simultaneous generation of many RNA-seq libraries in a single reaction
- (2015) Alexander A Shishkin et al. NATURE METHODS
- The exon junction complex as a node of post-transcriptional networks
- (2015) Hervé Le Hir et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
- (2014) Schraga Schwartz et al. Cell Reports
- Differential protein occupancy profiling of the mRNA transcriptome
- (2014) Markus Schueler et al. GENOME BIOLOGY
- High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
- (2013) Schraga Schwartz et al. CELL
- 3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts
- (2013) N. Spies et al. GENOME RESEARCH
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA
- (2013) N. Liu et al. RNA
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus
- (2012) Guramrit Singh et al. CELL
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Genome-wide analysis of long noncoding RNA stability
- (2012) M. B. Clark et al. GENOME RESEARCH
- Perispeckles are major assembly sites for the exon junction core complex
- (2012) Elisabeth Daguenet et al. MOLECULAR BIOLOGY OF THE CELL
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- CLIP-seq of eIF4AIII reveals transcriptome-wide mapping of the human exon junction complex
- (2012) Jérôme Saulière et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
- (2009) Christine Mayr et al. CELL
- The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay
- (2009) Niels H. Gehring et al. PLOS BIOLOGY
- Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells
- (2008) L. V. Sharova et al. DNA RESEARCH
- Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
- (2008) R. Sandberg et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now