Design and Synthesis of 3-Hydroxy-pyridin-4(1H)-ones–Ciprofloxacin Conjugates as Dual Antibacterial and Antibiofilm Agents against Pseudomonas aeruginosa

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

(2022) Christopher JL Murray et al.   LANCET

Enzyme‐Activated, Chemiluminescent Siderophore‐Dioxetane Probes Enable the Selective and Highly Sensitive Detection of Bacterial Pathogens

(2022) Carsten Peukert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reply to Kaye and Belley, “Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too!”

(2022) Mark S. Butler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tracking Uptake and Metabolism of Xenometallomycins Using a Multi-Isotope Tagging Strategy

(2022) Apurva Pandey et al.   ACS Infectious Diseases

Heavy-Metal Trojan Horse: Enterobactin-Directed Delivery of Platinum(IV) Prodrugs to Escherichia coli

(2022) Chuchu Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Pqs Quorum Sensing System Inhibitor as an Antibacterial Synergist against Multidrug-Resistant Pseudomonas aeruginosa

(2021) Jun Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Trends, Epidemiology, and Management of Multi-Drug Resistant Gram-Negative Bacterial Infections in the Hospitalized Setting

(2020) Sabrina Morris et al.   Antibiotics-Basel

Novel 2-Substituted 3-Hydroxy-1,6-dimethylpyridin-4(1H)-ones as Dual-Acting Biofilm Inhibitors of Pseudomonas aeruginosa

(2020) Jun Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa

(2020) Joscha Meiers et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Pseudomonas aeruginosa Biofilms

(2019) Marwa Taouai et al.   JOURNAL OF MEDICINAL CHEMISTRY

An overview of recent progress in siderophore-antibiotic conjugates

(2019) Huimin Kong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency

(2019) Apurva Pandey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic development — economic, regulatory and societal challenges

(2019) Christine Årdal et al.   NATURE REVIEWS MICROBIOLOGY

Dehydroxylation of alcohols for nucleophilic substitution

(2018) Jia Chen et al.   CHEMICAL COMMUNICATIONS

Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin–Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity

(2018) Wilma Neumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-inferiority trial

(2018) Simon Portsmouth et al.   LANCET INFECTIOUS DISEASES

Targeted Antibiotic Delivery: Selective Siderophore Conjugation with Daptomycin Confers Potent Activity against Multidrug Resistant Acinetobacter baumannii Both in Vitro and in Vivo

(2017) Manuka Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Deferiprone and Gallium-Protoporphyrin Have the Capacity to Potentiate the Activity of Antibiotics in Staphylococcus aureus Small Colony Variants

(2017) Katharina Richter et al.   Frontiers in Cellular and Infection Microbiology

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Modulation of Host Biology by Pseudomonas aeruginosa Quorum Sensing Signal Molecules: Messengers or Traitors

(2015) Yi-Chia Liu et al.   Frontiers in Microbiology

Trihydroxamate Siderophore–Fluoroquinolone Conjugates Are Selective Sideromycin Antibiotics that Target Staphylococcus aureus

(2013) Timothy A. Wencewicz et al.   BIOCONJUGATE CHEMISTRY

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

(2013) Natalia V. Kirienko et al.   Cell Host & Microbe

Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity

(2013) Matthew F. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Biscatecholate–Monohydroxamate Mixed Ligand Siderophore–Carbacephalosporin Conjugates are Selective Sideromycin Antibiotics that Target Acinetobacter baumannii

(2013) Timothy A. Wencewicz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ferrous Iron Is a Significant Component of Bioavailable Iron in Cystic Fibrosis Airways

(2013) R. C. Hunter et al.   mBio

Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam

(2012) Craig J. McPherson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Exploiting bacterial iron acquisition: siderophore conjugates

(2012) Cheng Ji et al.   Future Medicinal Chemistry

Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds and Evaluation of Enterobactin–Cargo Conjugate Uptake

(2012) Tengfei Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Low Levels of  -Lactam Antibiotics Induce Extracellular DNA Release and Biofilm Formation in Staphylococcus aureus

(2012) J. B. Kaplan et al.   mBio

Anti-Pseudomonas Activity of Frog Skin Antimicrobial Peptides in a Caenorhabditis elegans Infection Model: a Plausible Mode of Action In Vitro and In Vivo

(2010) D. Uccelletti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microtiter susceptibility testing of microbes growing on peg lids: a miniaturized biofilm model for high-throughput screening

(2010) Joe J Harrison et al.   Nature Protocols

A field guide to bacterial swarming motility

(2010) Daniel B. Kearns   NATURE REVIEWS MICROBIOLOGY

Identification of Catechin as One of the Flavonoids from Combretum albiflorum Bark Extract That Reduces the Production of Quorum-Sensing-Controlled Virulence Factors in Pseudomonas aeruginosa PAO1

(2009) O. M. Vandeputte et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents

(2009) Marvin J. Miller et al.   BIOMETALS

Copper and Quaternary Ammonium Cations Exert Synergistic Bactericidal and Antibiofilm Activity against Pseudomonas aeruginosa

(2008) J. J. Harrison et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Living on a surface: swarming and biofilm formation

(2008) Natalie Verstraeten et al.   TRENDS IN MICROBIOLOGY