Boosting lung accumulation of gallium with inhalable nano-embedded microparticles for the treatment of bacterial pneumonia

Approaches to Targeting Bacterial Biofilms in Cystic Fibrosis Airways

(2021) Isaac Martin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pulmonary biofilm-based chronic infections and inhaled treatment strategies

(2021) Li Ding et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Intra-tracheal administration increases gallium availability in lung: implications for antibacterial chemotherapy

(2021) Emma Mitidieri et al.   PHARMACOLOGICAL RESEARCH

Inhalation therapy devices for the treatment of obstructive lung diseases: the history of inhalers towards the ideal inhaler

(2020) Claudio Sorino et al.   European Journal of Internal Medicine

Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease

(2020) Mario Cazzola et al.   Expert Opinion on Drug Delivery

Chitosan-modified hyaluronic acid-based nanosized drug carriers

(2020) Árpád Turcsányi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Release mechanisms and molecular interactions of Pseudomonas aeruginosa extracellular DNA

(2020) Subendu Sarkar   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

(2020) Elio Rossi et al.   NATURE REVIEWS MICROBIOLOGY

An overview of gastrointestinal mucus rheology under different pH conditions and introduction to pH-dependent rheological interactions with PLGA and chitosan nanoparticles

(2020) Gustavo Ruiz-Pulido et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Challenges and strategies in drug delivery systems for treatment of pulmonary infections

(2019) Duy-Khiet Ho et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The role of mucus on drug transport and its potential to affect therapeutic outcomes

(2018) Xabier Murgia et al.   ADVANCED DRUG DELIVERY REVIEWS

Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier

(2018) Ivana d'Angelo et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Progress in understanding mucus abnormalities in cystic fibrosis airways

(2018) Jeffrey J. Wine et al.   Journal of Cystic Fibrosis

Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis

(2018) Michael D. Parkins et al.   CLINICAL MICROBIOLOGY REVIEWS

Antimicrobial Activity of Gallium Compounds on ESKAPE Pathogens

(2018) Sarah Hijazi et al.   Frontiers in Cellular and Infection Microbiology

Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

(2017) Monica Agnoletti et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The therapeutic potential of iron-targeting gallium compounds in human disease: From basic research to clinical application

(2017) Christopher R. Chitambar   PHARMACOLOGICAL RESEARCH

Gallium and its competing roles with iron in biological systems

(2016) Christopher R. Chitambar   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Large Porous Particles for Sustained Release of a Decoy Oligonucelotide and Poly(ethylenimine): Potential for Combined Therapy of Chronic Pseudomonas aeruginosa Lung Infections

(2016) Ivana d’Angelo et al.   BIOMACROMOLECULES

Disintegration of nano-embedded microparticles after deposition on mucus: A mechanistic study

(2016) Christian A. Ruge et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Development of inhalable hyaluronan/mannitol composite dry powders for flucytosine repositioning in local therapy of lung infections

(2016) G. Costabile et al.   JOURNAL OF CONTROLLED RELEASE

Iron acquisition in the cystic fibrosis lung and potential for novel therapeutic strategies

(2016) Jean Tyrrell et al.   MICROBIOLOGY-SGM

Pyoverdine and Proteases Affect the Response of Pseudomonas aeruginosa to Gallium in Human Serum

(2015) Carlo Bonchi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Overcoming barriers in Pseudomonas aeruginosa lung infections: Engineered nanoparticles for local delivery of a cationic antimicrobial peptide

(2015) Ivana d’Angelo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Simulated Biological Fluids with Possible Application in Dissolution Testing

(2015) Margareth R. C. Marques et al.   DISSOLUTION TECHNOLOGIES

Technological and practical challenges of dry powder inhalers and formulations

(2014) M. Hoppentocht et al.   ADVANCED DRUG DELIVERY REVIEWS

Promises and failures of gallium as an antibacterial agent

(2014) Fabrizia Minandri et al.   Future Microbiology

Interleukin 8 and Acute Lung Injury

(2013) Timothy Craig Allen et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Gallium-based anti-infectives: targeting microbial iron-uptake mechanisms

(2013) Andrew B Kelson et al.   CURRENT OPINION IN PHARMACOLOGY

In VitroandIn VivoAntimicrobial Activities of Gallium Nitrate against Multidrug-Resistant Acinetobacter baumannii

(2012) Luísa C. S. Antunes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting iron uptake to controlPseudomonas aeruginosainfections in cystic fibrosis

(2012) Daniel J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: Modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers

(2011) Francesca Ungaro et al.   JOURNAL OF CONTROLLED RELEASE

Hyaluronic acid/Chitosan nanoparticles as delivery vehicles for VEGF and PDGF-BB

(2010) Yolanda Parajó et al.   DRUG DELIVERY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of lung iron in determining the bacterial and host struggle in cystic fibrosis

(2009) D. W. Reid et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Iron acquisition by Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis

(2009) Iain L. Lamont et al.   BIOMETALS

Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma

(2009) F.A. Oyarzun-Ampuero et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS