Proteomic and Transcriptomic Responses Enable Clams to Correct the pH of Calcifying Fluids and Sustain Biomineralization in Acidified Environments

Keeping up with advances in qPCR pathogen detection: an example for QPX disease in hard clams

(2022) S Geraci-Yee et al.   DISEASES OF AQUATIC ORGANISMS

Transcriptomic, Proteomic, and Functional Assays Underline the Dual Role of Extrapallial Hemocytes in Immunity and Biomineralization in the Hard Clam Mercenaria mercenaria

(2022) Caroline Schwaner et al.   Frontiers in Immunology

Comparative analysis of the Mercenaria mercenaria genome provides insights into the diversity of transposable elements and immune molecules in bivalve mollusks

(2022) Sarah Farhat et al.   BMC GENOMICS

The silent loss of cell physiology hampers marine biosciences

(2022) Frank Melzner et al.   PLOS BIOLOGY

Oyster biomineralisation under ocean acidification: from genes to shell

(2021) Kanmani Chandra Rajan et al.   GLOBAL CHANGE BIOLOGY

Acid–base balance in the hæmolymph of European abalone (Haliotis tuberculata) exposed to CO2-induced ocean acidification

(2021) Stéphanie Auzoux-Bordenave et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Molecular mechanisms underlying responses of the Antarctic coral Malacobelemnon daytoni to ocean acidification

(2021) N. Servetto et al.   MARINE ENVIRONMENTAL RESEARCH

A proteomic analysis of the effect of ocean acidification on the haemocyte proteome of the South African abalone Haliotis midae

(2021) Sarah L. Carroll et al.   FISH & SHELLFISH IMMUNOLOGY

Experimental acidification increases susceptibility of Mercenaria mercenaria to infection by Vibrio species

(2020) Caroline Schwaner et al.   MARINE ENVIRONMENTAL RESEARCH

A simple serum depletion method for proteomics analysis

(2020) Alexandre Zougman et al.   BIOTECHNIQUES

Metabolomic and transcriptomic profiling reveals the alteration of energy metabolism in oyster larvae during initial shell formation and under experimental ocean acidification

(2020) Zhaoqun Liu et al.   Scientific Reports

Histological and Comparative Transcriptome Analyses Provide Insights Into the Immune Response in Pearl Sac Formation of Hyriopsis cumingii

(2020) Wenying Shen et al.   Frontiers in Marine Science

Intracellular pH regulation in mantle epithelial cells of the Pacific oyster, Crassostrea gigas

(2020) Kirti Ramesh et al.   Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology

In situ Measurements of pH, CA2+, and Dic Dynamics within the Extrapallial Fluid of the Ocean Quahog Arctica islandica

(2019) Kristina Stemmer et al.   JOURNAL OF SHELLFISH RESEARCH

Effects of acidification on the proteome during early development of Babylonia areolata

(2019) Guilan Di et al.   FEBS Open Bio

Ocean Acidification and Coastal Marine Invertebrates: Tracking CO2 Effects from Seawater to the Cell

(2019) Frank Melzner et al.   Annual Review of Marine Science

Applications of flow cytometry in molluscan immunology: Current status and trends

(2019) Thao Van Nguyen et al.   FISH & SHELLFISH IMMUNOLOGY

CO2-driven ocean acidification weakens mussel shell defense capacity and induces global molecular compensatory responses

(2019) Xinguo Zhao et al.   CHEMOSPHERE

Gene expression correlated with delay in shell formation in larval Pacific oysters (Crassostrea gigas) exposed to experimental ocean acidification provides insights into shell formation mechanisms

(2018) Pierre De Wit et al.   BMC GENOMICS

Bivalve shell formation in a naturally CO 2 -enriched habitat: Unraveling the resilience mechanisms from elemental signatures

(2018) Liqiang Zhao et al.   CHEMOSPHERE

Potential trade-offs between biomineralization and immunity revealed by shell properties and gene expression profiles of two closely relatedCrassostreaspecies

(2018) Anna V. Ivanina et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

CO 2 -induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective

(2018) Ruiwen Cao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Hemocytes in the extrapallial space of Pinctada fucata are involved in immunity and biomineralization

(2018) Jingliang Huang et al.   Scientific Reports

Ocean Acidification Affects the Cytoskeleton, Lysozymes, and Nitric Oxide of Hemocytes: A Possible Explanation for the Hampered Phagocytosis in Blood Clams, Tegillarca granosa

(2018) Wenhao Su et al.   Frontiers in Physiology

A Carbonic Anhydrase Serves as an Important Acid-Base Regulator in Pacific Oyster Crassostrea gigas Exposed to Elevated CO2: Implication for Physiological Responses of Mollusk to Ocean Acidification

(2017) Xiudan Wang et al.   MARINE BIOTECHNOLOGY

Ocean acidification adversely influences metabolism, extracellular pH and calcification of an economically important marine bivalve, Tegillarca granosa

(2017) Xinguo Zhao et al.   MARINE ENVIRONMENTAL RESEARCH

Mussel larvae modify calcifying fluid carbonate chemistry to promote calcification

(2017) Kirti Ramesh et al.   Nature Communications

Seawater acidification induced immune function changes of haemocytes in Mytilus edulis: a comparative study of CO2 and HCl enrichment

(2017) Tianli Sun et al.   Scientific Reports

Ocean acidification stimulates alkali signal pathway: A bicarbonate sensing soluble adenylyl cyclase from oyster Crassostrea gigas mediates physiological changes induced by CO 2 exposure

(2016) Xiudan Wang et al.   AQUATIC TOXICOLOGY

Chemical and biological impacts of ocean acidification along the west coast of North America

(2016) Richard A. Feely et al.   ESTUARINE COASTAL AND SHELF SCIENCE

Combined effects of seawater acidification and high temperature on hemocyte parameters in the thick shell mussel Mytilus coruscus

(2016) Fangli Wu et al.   FISH & SHELLFISH IMMUNOLOGY

Ocean acidification weakens the immune response of blood clam through hampering the NF-kappa β and toll-like receptor pathways

(2016) Saixi Liu et al.   FISH & SHELLFISH IMMUNOLOGY

Proteomic characterization of mucosal secretions in the eastern oyster, Crassostrea virginica

(2016) Emmanuelle Pales Espinosa et al.   Journal of Proteomics

Insights from the Shell Proteome: Biomineralization to Adaptation

(2016) Jaison Arivalagan et al.   MOLECULAR BIOLOGY AND EVOLUTION

Experimental design in ocean acidification research: problems and solutions

(2015) Christopher E. Cornwall et al.   ICES JOURNAL OF MARINE SCIENCE

Impact of ocean acidification on thermal tolerance and acid–base regulation of Mytilus edulis (L.) from the North Sea

(2015) Zora M.C. Zittier et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Immune responses to infectious diseases in bivalves

(2015) Bassem Allam et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

Comparative and quantitative proteomics reveal the adaptive strategies of oyster larvae to ocean acidification

(2015) R. Dineshram et al.   PROTEOMICS

Impact of Ocean Acidification on Marine Organisms—Unifying Principles and New Paradigms

(2015) Jason Hall-Spencer et al.   Water

Shotgun proteomics reveals physiological response to ocean acidification in Crassostrea gigas

(2014) Emma Timmins-Schiffman et al.   BMC GENOMICS

Molecular mechanisms underlying the physiological responses of the cold-water coral Desmophyllum dianthus to ocean acidification

(2014) M. Carreiro-Silva et al.   CORAL REEFS

Large Natural pH, CO2 and O2 Fluctuations in a Temperate Tidal Salt Marsh on Diel, Seasonal, and Interannual Time Scales

(2014) Hannes Baumann et al.   Estuaries and Coasts

Coastal ocean acidification: The other eutrophication problem

(2014) Ryan B. Wallace et al.   ESTUARINE COASTAL AND SHELF SCIENCE

Impacts of seawater acidification on mantle gene expression patterns of the Baltic Sea blue mussel: implications for shell formation and energy metabolism

(2012) Anne K. Hüning et al.   MARINE BIOLOGY

Spatial analysis of biomineralization associated gene expression from the mantle organ of the pearl oyster Pinctada maxima

(2011) Luke D Gardner et al.   BMC GENOMICS

Ocean Acidification: Present Conditions and Future Changes in a High-CO2 World

(2011) Richard Feely et al.   OCEANOGRAPHY

Meta-analysis reveals negative yet variable effects of ocean acidification on marine organisms

(2010) Kristy J. Kroeker et al.   ECOLOGY LETTERS

Carbonate constants for estuarine waters

(2010) Frank J. Millero   MARINE AND FRESHWATER RESEARCH

Moderate seawater acidification does not elicit long-term metabolic depression in the blue mussel Mytilus edulis

(2010) Jörn Thomsen et al.   MARINE BIOLOGY

Impact of Ocean Acidification on Energy Metabolism of Oyster, Crassostrea gigas—Changes in Metabolic Pathways and Thermal Response

(2010) Gisela Lannig et al.   Marine Drugs

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Transcriptomic response of sea urchin larvae Strongylocentrotus purpuratus to CO2-driven seawater acidification

(2009) A. E. Todgham et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Ocean Acidification and Its Potential Effects on Marine Ecosystems

(2008) John M. Guinotte et al.   Annals of the New York Academy of Sciences

Ocean Acidification: The Other CO2Problem

(2008) Scott C. Doney et al.   Annual Review of Marine Science

Effects of ocean acidification on the immune response of the blue mussel Mytilus edulis

(2008) R Bibby et al.   Aquatic Biology

Bicarbonate transport in cell physiology and disease

(2008) Emmanuelle Cordat et al.   BIOCHEMICAL JOURNAL

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Predicting the impact of ocean acidification on benthic biodiversity: What can animal physiology tell us?

(2008) Stephen Widdicombe et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Ocean acidification may increase calcification rates, but at a cost

(2008) H. L Wood et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES