Discovery of novel AdipoRon analogues as potent anti-inflammatory agents against nonalcoholic steatohepatitis

AdipoRon Attenuates Inflammation and Impairment of Cardiac Function Associated With Cardiopulmonary Bypass–Induced Systemic Inflammatory Response Syndrome

(2021) Alexander Jenke et al.   Journal of the American Heart Association

Proresolving lipid mediators and liver disease

(2021) Joan Clària et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Therapeutic effects of AdipoRon on liver inflammation and fibrosis induced by CCl4 in mice

(2020) Min Sha et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation

(2020) Liang Dai et al.   Journal of Chemical Information and Modeling

Nonalcoholic Steatohepatitis

(2020) Adam C. Sheka et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

AdipoRon, an adiponectin receptor agonist, protects contrast-induced nephropathy by suppressing oxidative stress and inflammation via activation of the AMPK pathway

(2020) Daqian Gu et al.   Clinical and Experimental Nephrology

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment

(2020) Yu Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease

(2020) Estefanía de Gregorio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification and Characterization of a Novel Adiponectin Receptor Agonist AdipoAI and its Anti‐Inflammatory Effects in vitro and in vivo

(2020) Wei Qiu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid

(2020) Liu Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Mortality in biopsy-confirmed nonalcoholic fatty liver disease: results from a nationwide cohort

(2020) Tracey G Simon et al.   GUT

Adiponectin receptor agonist AdipoRon relieves endotoxin-induced acute hepatitis in mice

(2019) Wen-Ze Xiao et al.   CHINESE MEDICAL JOURNAL

Molecular actions of PPARα in lipid metabolism and inflammation

(2018) Nadia Bougarne et al.   ENDOCRINE REVIEWS

Inflammation and fibrosis

(2018) Matthias Mack   MATRIX BIOLOGY

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk

(2016) Jennifer H. Stern et al.   Cell Metabolism

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

(2013) Miki Okada-Iwabu et al.   NATURE

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY