Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism

Whole life exposure to low dose cadmium alters diet-induced NAFLD

(2022) Jamie L. Young et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cadmium perturbed metabolomic signature in pancreatic beta cells correlates with disturbed metabolite profile in human urine

(2022) Huihui Hong et al.   ENVIRONMENT INTERNATIONAL

Trace element and lipidomic analysis of bottlenose dolphin blubber from the Yucatan coast: Lipid composition relationships

(2022) Ixchel M. Ruiz-Hernández et al.   CHEMOSPHERE

Cadmium exposure impairs pancreatic β-cell function and exaggerates diabetes by disrupting lipid metabolism

(2021) Huihui Hong et al.   ENVIRONMENT INTERNATIONAL

Dysregulation of autophagy acts as a pathogenic mechanism of non-alcoholic fatty liver disease (NAFLD) induced by common environmental pollutants

(2021) Yao Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Puerarin attenuates cadmium-induced hepatic lipid metabolism disorder by inhibiting oxidative stress and inflammation in mice

(2021) Xue-Mei Wan et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cadmium chloride induces non-alcoholic fatty liver disease in rats by stimulating miR-34a/SIRT1/FXR/p53 axis

(2021) Ali S. Alshehri et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis

(2021) Anqi Kong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Integration of omics analysis and atmospheric pressure MALDI mass spectrometry imaging reveals the cadmium toxicity on female ICR mouse

(2021) Ting Zeng et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Delta-5-desaturase: A novel therapeutic target for cancer management

(2021) Lizhi Pang et al.   Translational Oncology

The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3

(2021) Qing Zhang et al.   Nature Communications

Association of urinary cadmium, circulating fatty acids, and risk of gestational diabetes mellitus: A nested case-control study in China

(2020) Xinping Li et al.   ENVIRONMENT INTERNATIONAL

Gut microbiota and lipid metabolism alterations in mice induced by oral cadmium telluride quantum dots

(2020) Xiaohui Li et al.   JOURNAL OF APPLIED TOXICOLOGY

Dietary cadmium exposure causes elevation of blood ApoE with triglyceride level in mice

(2020) Haitao Liu et al.   BIOMETALS

Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism

(2020) Priyanka Sharma et al.   TOXICOLOGY IN VITRO

Cadmium induces epithelial–mesenchymal transition and migration of renal cancer cells by increasing PGE2 through a cAMP/PKA-COX2 dependent mechanism

(2020) Haifeng Shi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

EpCAM-Targeted 3WJ RNA Nanoparticle Harboring Delta-5-Desaturase siRNA Inhibited Lung Tumor Formation via DGLA Peroxidation

(2020) Lizhi Pang et al.   Molecular Therapy-Nucleic Acids

Expression of Cytosolic Phospholipase A2 (cPLA2)-Arachidonic Acid (AA)-Cyclooxygenase-2 (COX-2) Pathway Factors in Lung Cancer Patients and Its Implication in Lung Cancer Early Detection and Prognosis

(2019) Chunxia Xin et al.   MEDICAL SCIENCE MONITOR

Exploring the interactions between polyunsaturated fatty acids and cadmium in rainbow trout liver cells: A genetic and proteomic study

(2018) Aline Ferain et al.   AQUATIC TOXICOLOGY

Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung

(2018) Xin Hu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dyslipdemia induced by chronic low dose co-exposure to lead, cadmium and manganese in rats: the role of oxidative stress

(2017) Olusola Olalekan Oladipo et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Metabonomics analysis of serum from rats given long-term and low-level cadmium by ultra-performance liquid chromatography–mass spectrometry

(2017) Liyan Hu et al.   XENOBIOTICA

Endoplasmic reticulum stress and calcium imbalance are involved in cadmium-induced lipid aberrancy in Saccharomyces cerevisiae

(2016) Selvaraj Rajakumar et al.   CELL STRESS & CHAPERONES

Cadmium Exposure is Associated with the Prevalence of Dyslipidemia

(2016) Zhou Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sex-Dependent Effects of Cadmium Exposure in Early Life on Gut Microbiota and Fat Accumulation in Mice

(2016) Qian Ba et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs

(2016) Xiaoyu Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Knockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-γ-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2

(2016) Yi Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

(2015) D. Lee Gorden et al.   JOURNAL OF LIPID RESEARCH

Functional genomics and metabolomics reveal the toxicological effects of cadmium in Mus musculus mice

(2015) M. A. García-Sevillano et al.   Metabolomics

Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice

(2015) Young-Mi Go et al.   TOXICOLOGICAL SCIENCES

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

(2015) Xin Rong et al.   eLife

Positive Effects of Soy Lecithin-Derived Phosphatidylserine plus Phosphatidic Acid on Memory, Cognition, Daily Functioning, and Mood in Elderly Patients with Alzheimer’s Disease and Dementia

(2014) Margret I. Moré et al.   ADVANCES IN THERAPY

Cadmium supplement triggers endoplasmic reticulum stress response and cytotoxicity in primary chicken hepatocytes

(2014) Cheng-Cheng Shao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Blood cadmium concentration and lipid profile in Korean adults

(2011) Kisok Kim   ENVIRONMENTAL RESEARCH

Randomized, Placebo-Controlled Phase III Study of Docetaxel Plus Carboplatin With Celecoxib and Cyclooxygenase-2 Expression As a Biomarker for Patients With Advanced Non–Small-Cell Lung Cancer: The NVALT-4 Study

(2011) Harry J.M. Groen et al.   JOURNAL OF CLINICAL ONCOLOGY

Cadmium exposure-induced alterations in the lipid/phospholipids composition of rat brain microsomes and mitochondria

(2009) Hiren R. Modi et al.   NEUROSCIENCE LETTERS