Considerations for the Use of Long-Acting and Extended-Release Agents During Pregnancy and Lactation

Perspectives on preparing for long-acting injectable treatment for HIV among consumer, clinical and nonclinical stakeholders: A qualitative study exploring the anticipated challenges and opportunities for implementation in Los Angeles County

(2022) Oluwadamilola Jolayemi et al.   PLoS One

Clinical translation of long-acting drug delivery formulations

(2022) Wei Li et al.   Nature Reviews Materials

Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

(2022) Sinead Delany-Moretlwe et al.   LANCET

A Holistic Review of the Preclinical Landscape for Long-Acting Anti-infective Drugs Using HIV as a Paradigm

(2022) Megan Neary et al.   CLINICAL INFECTIOUS DISEASES

Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa

(2021) Rebecca Acquah et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Drug development research in pregnant and lactating women

(2021) Zhaoxia Ren et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pharmacokinetics and Drug–Drug Interactions of Long-Acting Intramuscular Cabotegravir and Rilpivirine

(2021) Daryl Hodge et al.   CLINICAL PHARMACOKINETICS

Pharmacokinetics and Safety of 3 Months of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention in Pregnant Women

(2021) Jyoti S Mathad et al.   CLINICAL INFECTIOUS DISEASES

Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester

(2021) Babajide Shenkoya et al.   Frontiers in Pediatrics

Impact of long-acting therapies on the global HIV epidemic

(2021) Nomathemba C. Chandiwana et al.   AIDS

Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

(2021) Nupur Chaphekar et al.   Frontiers in Pediatrics

Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection

(2020) Chloe Orkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placental Transfer of the integrase strand inhibitors cabotegravir and bictegravir in the Ex-Vivo Human Cotyledon Perfusion Model

(2020) Lucile Pencolé et al.   AIDS

Pharmacokinetics, safety and tolerability of long‐acting parenteral intramuscular injection formulations of doravirine

(2020) Ka Lai Yee et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

The incidence of HIV and associated risk factors among pregnant women in Kabarole District, Uganda

(2020) Hannah Schumann et al.   PLoS One

Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2018 and 2019

(2020) Paul Barrow et al.   REPRODUCTIVE TOXICOLOGY

Preferences for long‐acting Pre‐Exposure Prophylaxis (PrEP) for HIV prevention among South African youth: results of a discrete choice experiment

(2020) Alexandra M Minnis et al.   Journal of the International AIDS Society

Use of Model-Informed Drug Development to Streamline Development of Long-Acting Products: Can these Successes Be Translated to Long-Acting Hormonal Contraceptives?

(2020) Li Li et al.   Annual Review of Pharmacology and Toxicology

Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies?

(2020) Donald E. Ingber   Advanced Science

Importance of prospective studies in pregnant and breastfeeding women living with HIV

(2019) Angela Colbers et al.   CLINICAL INFECTIOUS DISEASES

The global prevalence of latent tuberculosis: a systematic review and meta-analysis

(2019) Adam Cohen et al.   EUROPEAN RESPIRATORY JOURNAL

Injectable, long-acting PLGA formulations: Analyzing PLGA and understanding microparticle formation

(2019) Kinam Park et al.   JOURNAL OF CONTROLLED RELEASE

Review article: direct-acting antivirals for the treatment of HCV during pregnancy and lactation - implications for maternal dosing, foetal exposure, and safety for mother and child

(2019) Jolien J. M. Freriksen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

(2019) Martin J. Smilkstein et al.   MALARIA JOURNAL

Predictors of Viremia in Postpartum Women on Antiretroviral Therapy

(2019) Risa M. Hoffman et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Atovaquone-proguanil exposure in pregnancy and risk for adverse fetal and infant outcomes: A retrospective analysis

(2019) Julie R. Gutman et al.   Travel Medicine and Infectious Disease

Using mechanistic physiologically-based pharmacokinetic models to assess prenatal drug exposure: Thalidomide versus efavirenz as case studies

(2019) Shakir Adeyinka Atoyebi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Predicting drug-drug interactions between rifampicin and long-acting cabotegravir and rilpivirine using PBPK modelling

(2018) Rajith K R Rajoli et al.   JOURNAL OF INFECTIOUS DISEASES

HIV incidence among pregnant and postpartum women in a high prevalence setting

(2018) Rhoderick Machekano et al.   PLoS One

Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women

(2016) Anna H. Tran et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection

(2016) Lauren M. Cohee et al.   MALARIA JOURNAL

Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics

(2015) A Olagunju et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis

(2014) A G A Jackson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

GSK1265744 Pharmacokinetics in Plasma and Tissue After Single-Dose Long-Acting Injectable Administration in Healthy Subjects

(2014) William Spreen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Tuberculosis in pregnancy: an estimate of the global burden of disease

(2014) Jordan Sugarman et al.   Lancet Global Health

Pharmacogenetic Study on Risperidone Long-Acting Injection

(2013) Eva Choong et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice

(2012) Shujuan Chen et al.   HEPATOLOGY

Evolving knowledge of the teratogenicity of medications in human pregnancy

(2011) Margaret P. Adam et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy

(2009) F.F. Tessa Ververs et al.   CLINICAL PHARMACOKINETICS

Factors Associated With Failure To Complete Isoniazid Treatment for Latent Tuberculosis Infection in Rhode Island

(2007) Awewura Kwara et al.   CHEST