Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

(2021) Akihiro Kaneshige et al.   Cell Stem Cell

Identification of splice regulators of fibronectin-EIIIA and EIIIB by direct measurement of exon usage in a flow-cytometry based CRISPR screen

(2021) Jessica A. Hensel et al.   Scientific Reports

Thrombospondin-1 in Maladaptive Aging Responses: A Concept Whose Time Has Come

(2020) Jeffrey S. Isenberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength

(2020) A. R. Palla et al.   SCIENCE

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Adult stem cells at work: regenerating skeletal muscle

(2019) Manuel Schmidt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function

(2019) Antoine de Morree et al.   SCIENCE

Muscle strength and size are associated with motor unit connectivity in aged mice

(2018) Kajri A. Sheth et al.   NEUROBIOLOGY OF AGING

Transmission genetics of drug-resistant hepatitis C virus

(2018) Nicholas van Buuren et al.   eLife

The exerkine apelin reverses age-associated sarcopenia

(2018) Claire Vinel et al.   NATURE MEDICINE

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease

(2018) Peter Feige et al.   Cell Stem Cell

High-resolution myogenic lineage mapping by single-cell mass cytometry

(2017) Ermelinda Porpiglia et al.   NATURE CELL BIOLOGY

Mass Cytometry: Single Cells, Many Features

(2016) Matthew H. Spitzer et al.   CELL

Sarcopenia Is Recognized as an Independent Condition by an International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM) Code

(2016) Li Cao et al.   Journal of the American Medical Directors Association

Regenerative decline of stem cells in sarcopenia

(2016) Pedro Sousa-Victor et al.   MOLECULAR ASPECTS OF MEDICINE

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

(2016) Michelle Rozo et al.   NATURE MEDICINE

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

(2016) Laura Lukjanenko et al.   NATURE MEDICINE

Automated mapping of phenotype space with single-cell data

(2016) Nikolay Samusik et al.   NATURE METHODS

Alternative polyadenylation of mRNA precursors

(2016) Bin Tian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Thrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells

(2016) Qi Gao et al.   Cell Death & Disease

Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair

(2016) Ellen L. Mintz et al.   Jove-Journal of Visualized Experiments

A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry

(2015) Eli R. Zunder et al.   Cell Stem Cell

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

(2015) Binyamin D. Berkovits et al.   NATURE

The central role of muscle stem cells in regenerative failure with aging

(2015) Helen M Blau et al.   NATURE MEDICINE

miR-487b promotes human umbilical vein endothelial cell proliferation, migration, invasion and tube formation through regulating THBS1

(2015) Nianping Feng et al.   NEUROSCIENCE LETTERS

Muscle stem cells contribute to myofibres in sedentary adult mice

(2015) Alexandra C. Keefe et al.   Nature Communications

Pervasive satellite cell contribution to uninjured adult muscle fibers

(2015) Bradley Pawlikowski et al.   Skeletal Muscle

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

STAT3 signaling controls satellite cell expansion and skeletal muscle repair

(2014) Matthew Timothy Tierney et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

SMASH – semi-automatic muscle analysis using segmentation of histology: a MATLAB application

(2014) Lucas R Smith et al.   Skeletal Muscle

Single-cell mass cytometry for analysis of immune system functional states

(2013) Zach B Bjornson et al.   CURRENT OPINION IN IMMUNOLOGY

Angiogenic response to passive movement and active exercise in individuals with peripheral arterial disease

(2013) B. Hoier et al.   JOURNAL OF APPLIED PHYSIOLOGY

Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors

(2013) Sukhbir Kaur et al.   Scientific Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

(2012) Michael G. Berg et al.   CELL

Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study

(2012) Francesco Landi et al.   CLINICAL NUTRITION

A platinum-based covalent viability reagent for single-cell mass cytometry

(2012) Harris G. Fienberg et al.   CYTOMETRY PART A

Intense intermittent exercise provides weak stimulus for vascular endothelial growth factor secretion and capillary growth in skeletal muscle

(2012) B. Hoier et al.   EXPERIMENTAL PHYSIOLOGY

CD47high Expression on CD4 Effectors Identifies Functional Long-Lived Memory T Cell Progenitors

(2012) V. Q. Van et al.   JOURNAL OF IMMUNOLOGY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Analysis of alternative cleavage and polyadenylation by 3′ region extraction and deep sequencing

(2012) Mainul Hoque et al.   NATURE METHODS

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

RNA-binding proteins and gene regulation in myogenesis

(2011) Luciano H. Apponi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

(2010) Daisuke Kaida et al.   NATURE

Thrombospondin-1 inhibition of vascular smooth muscle cell responses occurs via modulation of both cAMP and cGMP

(2010) Mingyi Yao et al.   PHARMACOLOGICAL RESEARCH

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

(2009) Siddhartha Jaiswal et al.   CELL

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice

(2008) Riikka Kivelä et al.   Cardiovascular Diabetology

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

(2008) Y. Rolland et al.   Journal of Nutrition Health & Aging

Self-renewal and expansion of single transplanted muscle stem cells

(2008) Alessandra Sacco et al.   NATURE