Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation

Metabolic determination of cell fate through selective inheritance of mitochondria

(2022) Julia Döhla et al.   NATURE CELL BIOLOGY

DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets

(2022) Sean B. Wilson et al.   Genome Medicine

Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context

(2022) Pieter Goossens et al.   Cell Metabolism

Vasculogenesis in kidney organoids upon transplantation

(2022) Marije Koning et al.   npj Regenerative Medicine

Spatial transcriptional mapping of the human nephrogenic program

(2021) Nils O. Lindström et al.   DEVELOPMENTAL CELL

Single Cell Sequencing and Kidney Organoids Generated from Pluripotent Stem Cells

(2020) Haojia Wu et al.   Clinical Journal of the American Society of Nephrology

Single-cell RNA sequencing of human kidney

(2020) Jinling Liao et al.   Scientific Data

In Vivo Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell–Derived Kidney Organoids

(2020) Cathelijne W. van den Berg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing

(2020) Dmitriy Korostin et al.   PLoS One

Validation of MALDI-MS imaging data of selected membrane lipids in murine brain with and without laser postionization by quantitative nano-HPLC-MS using laser microdissection

(2020) Fabian B. Eiersbrock et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation

(2020) Poonam Dhillon et al.   Cell Metabolism

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

(2019) Mazène Hochane et al.   PLOS BIOLOGY

Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data

(2019) Jevin Z. Clark et al.   KIDNEY INTERNATIONAL

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

(2019) Paul T. Brinkkoetter et al.   Cell Reports

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

A Toolbox to Characterize Human Induced Pluripotent Stem Cell–Derived Kidney Cell Types and Organoids

(2019) Jessica M. Vanslambrouck et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning

(2018) Nils O. Lindström et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mapping kidney cellular complexity

(2018) Benjamin D. Humphreys   SCIENCE

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

(2018) Cathelijne W. van den Berg et al.   Stem Cell Reports

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

(2018) Matthew D. Young et al.   SCIENCE

Evaluation of variability in human kidney organoids

(2018) Belinda Phipson et al.   NATURE METHODS

Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR

(2018) Paul Heinrich et al.   Scientific Reports

Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism

(2017) Jiao Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Renal metabolism in 2017: Glycolytic adaptation and progression of kidney disease

(2017) Ton J. Rabelink et al.   Nature Reviews Nephrology

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

A reference human genome dataset of the BGISEQ-500 sequencer

(2017) Jie Huang et al.   GigaScience

Mitochondrial Pathology and Glycolytic Shift during Proximal Tubule Atrophy after Ischemic AKI

(2016) R. Lan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data

(2016) Walid M. Abdelmoula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

De novodiscovery of phenotypic intratumour heterogeneity using imaging mass spectrometry

(2014) Benjamin Balluff et al.   JOURNAL OF PATHOLOGY

Acetate supplementation increases brain histone acetylation and inhibits histone deacetylase activity and expression

(2011) Mahmoud L. Soliman et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells

(2009) Carol B. Ware et al.   Cell Stem Cell