RAB5C, a new mRNA binding target of HuR, regulates breast cancer cell proliferation

HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner

(2020) Quan Zhao et al.   RNA Biology

The RNA-binding protein HuR is a negative regulator in adipogenesis

(2020) Diana Teh Chee Siang et al.   Nature Communications

Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling

(2020) Jian Heng et al.   PLOS BIOLOGY

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

(2020) Marta Palomo-Irigoyen et al.   JOURNAL OF CLINICAL INVESTIGATION

RAB5A promotes the formation of filopodia in pancreatic cancer cells via the activation of cdc42 and β1-integrin

(2020) Ziyan Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long non‑coding RNA CASC19 promotes glioma progression by modulating the miR‑454‑3p/RAB5A axis and is associated with unfavorable MRI features

(2020) Yong‑Juan Wu et al.   ONCOLOGY REPORTS

Blockade of miR-3614 maturation by IGF2BP3 increases TRIM25 expression and promotes breast cancer cell proliferation

(2019) Zhenzhen Wang et al.   EBioMedicine

Breast Cancer Treatment

(2019) Adrienne G. Waks et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1/Rab5/Rac1 pathway

(2019) Weiguang Liu et al.   Cancer Cell International

Breast cancer

(2019) Nadia Harbeck et al.   Nature Reviews Disease Primers

A brave new world of RNA-binding proteins

(2018) Matthias W. Hentze et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of RNA-binding protein HuR facilitates cellular senescence through posttranscriptional regulation of TIN2 mRNA

(2018) Ji Hoon Lee et al.   NUCLEIC ACIDS RESEARCH

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium

(2011) T Kurosu et al.   BRITISH JOURNAL OF CANCER

Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1-related epidermal growth factor signaling pathway

(2010) Zhen Zhao et al.   CANCER SCIENCE

RNA-binding proteins and post-transcriptional gene regulation

(2008) Tina Glisovic et al.   FEBS LETTERS