HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

Malignant Peripheral Nerve Sheath Tumors: From Epigenome to Bedside

(2019) Justin Korfhage et al.   MOLECULAR CANCER RESEARCH

Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms

(2018) Jody F. Longo et al.   ADVANCES IN ANATOMIC PATHOLOGY

Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis

(2018) Lai Man Natalie Wu et al.   CANCER CELL

RNA regulons in cancer and inflammation

(2018) Laura Simone Bisogno et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Interfering with HuR–RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors

(2018) Leonardo Manzoni et al.   JOURNAL OF MEDICINAL CHEMISTRY

A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes

(2018) Gabrielle Perron et al.   Cell Reports

RNA Binding Protein, HuR, Regulates SCN5A Expression Through Stabilizing MEF2C transcription factor mRNA

(2018) Anyu Zhou et al.   Journal of the American Heart Association

Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene

(2017) Barbara Fontanals-Cirera et al.   MOLECULAR CELL

Neoplasms With Schwannian Differentiation Express Transcription Factors Known to Regulate Normal Schwann Cell Development

(2017) Peter Pytel et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

The Challenge of Cancer Genomics in Rare Nervous System Neoplasms

(2016) Steven L. Carroll   AMERICAN JOURNAL OF PATHOLOGY

UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis

(2016) Laurence Wurth et al.   CANCER CELL

A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer

(2016) Daniel Dauch et al.   NATURE MEDICINE

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder

(2016) Jiawei Guo et al.   Oncotarget

RNA-binding proteins, multifaceted translational regulators in cancer

(2015) Laurence Wurth et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Lin28b Is Sufficient to Drive Liver Cancer and Necessary for Its Maintenance in Murine Models

(2014) Liem H. Nguyen et al.   CANCER CELL

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

(2014) Annie M. Tremblay et al.   CANCER CELL

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies

(2014) Thomas De Raedt et al.   NATURE

Malignant Peripheral Nerve Sheath Tumors

(2014) M. Farid et al.   ONCOLOGIST

BET Bromodomain Inhibition Triggers Apoptosis of NF1-Associated Malignant Peripheral Nerve Sheath Tumors through Bim Induction

(2014) Amish J. Patel et al.   Cell Reports

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

(2013) Bjoern Chapuy et al.   CANCER CELL

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Mechanisms coordinating ELAV/Hu mRNA regulons

(2013) Laura E Simone et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Profiling post-transcriptionally networked mRNA subsets using RIP-Chip and RIP-Seq

(2013) Sabarinath Jayaseelan et al.   METHODS

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

(2013) Eric P Rahrmann et al.   NATURE GENETICS

Canonical Wnt/β-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance

(2013) Adrienne L. Watson et al.   Cancer Discovery

Survivin Is a Viable Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors

(2012) M. P. Ghadimi et al.   CLINICAL CANCER RESEARCH

Ras-Driven Transcriptome Analysis Identifies Aurora Kinase A as a Potential Malignant Peripheral Nerve Sheath Tumor Therapeutic Target

(2012) A. V. Patel et al.   CLINICAL CANCER RESEARCH

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors

(2012) Walter J. Jessen et al.   JOURNAL OF CLINICAL INVESTIGATION

The RNA-Binding Protein Human Antigen R Controls Global Changes in Gene Expression during Schwann Cell Development

(2012) M. Iruarrizaga-Lejarreta et al.   JOURNAL OF NEUROSCIENCE

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Key contribution of CPEB4-mediated translational control to cancer progression

(2011) Elena Ortiz-Zapater et al.   NATURE MEDICINE

Posttranscriptional regulation of cancer traits by HuR

(2010) Kotb Abdelmohsen et al.   Wiley Interdisciplinary Reviews-RNA

Aurora kinase A is a target of Wnt/ -catenin involved in multiple myeloma disease progression

(2009) J. Dutta-Simmons et al.   BLOOD

Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene

(2009) Shyra J. Miller et al.   EMBO Molecular Medicine

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES