Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy

Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics

(2014) Randal J. Kaufman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation

(2014) Matthew J. Robson et al.   EXPERIMENTAL NEUROLOGY

Apoptosis Signal Regulating Kinase 1 (ASK1): Potential as a Therapeutic Target for Alzheimer’s Disease

(2014) Juhyun Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ubiquitination of Inositol-requiring Enzyme 1 (IRE1) by the E3 Ligase CHIP Mediates the IRE1/TRAF2/JNK Pathway

(2014) Xu Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repeated Mild Traumatic Brain Injury Causes Chronic Neuroinflammation, Changes in Hippocampal Synaptic Plasticity, and Associated Cognitive Deficits

(2014) Stephanie L Aungst et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Docosahexaenoic Acid Reduces ER Stress and Abnormal Protein Accumulation and Improves Neuronal Function Following Traumatic Brain Injury

(2014) G. Begum et al.   JOURNAL OF NEUROSCIENCE

Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle Development

(2014) Brandon Peter Lucke-Wold et al.   JOURNAL OF NEUROTRAUMA

The Spectrum of Neurobehavioral Sequelae after Repetitive Mild Traumatic Brain Injury: A Novel Mouse Model of Chronic Traumatic Encephalopathy

(2014) Anthony L. Petraglia et al.   JOURNAL OF NEUROTRAUMA

Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response

(2014) Nobuhiko Hiramatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells

(2014) Ana I. Plácido et al.   MOLECULAR NEUROBIOLOGY

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

(2014) Claudio Hetz et al.   NATURE REVIEWS NEUROSCIENCE

Metallothionein prevents intermittent hypoxia-induced cardiac endoplasmic reticulum stress and cell death likely via activation of Akt signaling pathway in mice

(2014) Shanshan Zhou et al.   TOXICOLOGY LETTERS

Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel

(2014) Thor D Stein et al.   Alzheimers Research & Therapy

Associations Between Cerebral Small-Vessel Disease and Alzheimer Disease Pathology as Measured by Cerebrospinal Fluid Biomarkers

(2014) Maartje I. Kester et al.   JAMA Neurology

The neuropathology of sport

(2013) Ann C. McKee et al.   ACTA NEUROPATHOLOGICA

PET Scanning of Brain Tau in Retired National Football League Players: Preliminary Findings

(2013) Gary W. Small et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice

(2013) Eun-Bum Kang et al.   APOPTOSIS

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1–40 peptide in brain endothelial cells

(2013) Ana Catarina R.G. Fonseca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chronic Traumatic Encephalopathy: Where Are We and Where Are We Going?

(2013) Jesse Mez et al.   Current Neurology and Neuroscience Reports

Physiological release of endogenous tau is stimulated by neuronal activity

(2013) Amy M Pooler et al.   EMBO REPORTS

Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats

(2013) Ryan C. Turner et al.   EXPERIMENTAL NEUROLOGY

An Unbiased Approach to Identifying Tau Kinases That Phosphorylate Tau at Sites Associated with Alzheimer Disease

(2013) Annalisa Cavallini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study

(2013) Y. Freund Levi et al.   JOURNAL OF INTERNAL MEDICINE

Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation

(2013) J. F. Abisambra et al.   JOURNAL OF NEUROSCIENCE

Omega-3 Fatty Acids as a Putative Treatment for Traumatic Brain Injury

(2013) Linda Hasadsri et al.   JOURNAL OF NEUROTRAUMA

Evidence for the Therapeutic Efficacy of Either Mild Hypothermia or Oxygen Radical Scavengers after Repetitive Mild Traumatic Brain Injury

(2013) Takashi Miyauchi et al.   JOURNAL OF NEUROTRAUMA

Functional Status after Blast-Plus-Impact Complex Concussive Traumatic Brain Injury in Evacuated United States Military Personnel

(2013) Christine L. MacDonald et al.   JOURNAL OF NEUROTRAUMA

Sport-Related Concussions: A Review of Epidemiology, Challenges in Diagnosis, and Potential Risk Factors

(2013) James M. Noble et al.   NEUROPSYCHOLOGY REVIEW

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

GADD34 induces cell death through inactivation of Akt following traumatic brain injury

(2013) J M Farook et al.   Cell Death & Disease

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

(2013) Matthew D. Shoulders et al.   Cell Reports

ER Stress and Effects of DHA as an ER Stress Inhibitor

(2013) Gulnaz Begum et al.   Translational Stroke Research

Blast overpressure induces shear-related injuries in the brain of rats exposed to a mild traumatic brain injury

(2013) Miguel A Sosa et al.   Acta Neuropathologica Communications

The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer’s disease

(2013) Lauren D Stutzbach et al.   Acta Neuropathologica Communications

The spectrum of disease in chronic traumatic encephalopathy

(2012) Ann C. McKee et al.   BRAIN

Endoplasmic reticulum: The unfolded protein response is tangled in neurodegeneration

(2012) Jeroen J.M. Hoozemans et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Concussive Injury before or after Controlled Cortical Impact Exacerbates Histopathology and Functional Outcome in a Mixed Traumatic Brain Injury Model in Mice

(2012) Heda R. Dapul et al.   JOURNAL OF NEUROTRAUMA

Protein-Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation

(2012) D. Ron et al.   Cold Spring Harbor Perspectives in Biology

Preconditioning for Traumatic Brain Injury

(2012) Shoji Yokobori et al.   Translational Stroke Research

Mechanisms of Primary Blast-Induced Traumatic Brain Injury: Insights from Shock-Wave Research

(2011) Atsuhiro Nakagawa et al.   JOURNAL OF NEUROTRAUMA

Does IGF-1 administration after a mild traumatic brain injury in mice activate the adaptive arm of ER stress?

(2011) Vardit Rubovitch et al.   NEUROCHEMISTRY INTERNATIONAL

Emerging Histomorphologic Phenotypes of Chronic Traumatic Encephalopathy in American Athletes

(2011) Bennet Omalu et al.   NEUROSURGERY

Internal Jugular Vein Compression Mitigates Traumatic Axonal Injury in a Rat Model by Reducing the Intracranial Slosh Effect

(2011) David W. Smith et al.   NEUROSURGERY

ER Stress Inhibits mTORC2 and Akt Signaling Through GSK-3 -Mediated Phosphorylation of Rictor

(2011) C.-H. Chen et al.   Science Signaling

Long-term Consequences of Repetitive Brain Trauma: Chronic Traumatic Encephalopathy

(2011) Robert A. Stern et al.   PM&R

Chronic Traumatic Encephalopathy, Suicides and Parasuicides in Professional American Athletes

(2010) Bennet I. Omalu et al.   AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY

TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

(2010) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat

(2010) V.A. DiNapoli et al.   NEUROSCIENCE

Chronic Traumatic Encephalopathy

(2010) Thomas Watanabe et al.   PM&R

Chronic traumatic encephalopathy in a professional American wrestler

(2010) Bennet I. Omalu et al.   Journal of Forensic Nursing

Phosphorylation of tau at Ser214 mediates its interaction with 14-3-3 protein: implications for the mechanism of tau aggregation

(2008) Golam Sadik et al.   JOURNAL OF NEUROCHEMISTRY