Mitochondria-Targeting and Multiresponsive Nanoplatform Based on AIEgens for Synergistic Chemo-Photodynamic Therapy and Enhanced Immunotherapy

Recent molecular design strategies for efficient photodynamic therapy and its synergistic therapy based on AIE photosensitizers

(2022) Jinxi Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Self-Guiding Polymeric Prodrug Micelles with Two Aggregation-Induced Emission Photosensitizers for Enhanced Chemo-Photodynamic Therapy

(2021) Xiaoqing Yi et al.   ACS Nano

Combination Chemo‐Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti‐PD‐1

(2021) Xiangsheng Liu et al.   Advanced Science

Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future

(2021) Razan Alzeibak et al.   Journal for ImmunoTherapy of Cancer

Liposome trade-off strategy in mitochondria-targeted NIR-cyanine: balancing blood circulation and cell retention for enhanced antitumor phototherapy in vivo

(2021) Xianghan Zhang et al.   Nano Research

Photodynamic therapy synergizes with PD-L1 checkpoint blockade for immunotherapy of CRC by multifunctional nanoparticles

(2021) Zeting Yuan et al.   MOLECULAR THERAPY

Fast Broad-Spectrum Staining and Photodynamic Inhibition of Pathogenic Microorganisms by a Water-Soluble Aggregation-Induced Emission Photosensitizer

(2021) Qi Zhou et al.   Frontiers in Chemistry

Three-Pronged Attack by Homologous Far-Red/NIR AIEgens to Achieve "1+1+1>3" Synergistic Enhanced Photodynamic Therapy

(2020) Wenhan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress of hypoxia-modulated multifunctional nanomedicines to enhance photodynamic therapy: Opportunities, challenges, and future development

(2020) Yixin Sun et al.   Acta Pharmaceutica Sinica B

Poly(l-glutamic acid)-Based Zwitterionic Polymer in a Charge Conversional Shielding System for Gene Therapy of Malignant Tumors

(2020) Jie Chen et al.   ACS Applied Materials & Interfaces

Multifunctional nano-photosensitizer: A carrier-free aggregation-induced emission nanoparticle with efficient photosensitization and pH-responsibility

(2020) Guohui Cheng et al.   CHEMICAL ENGINEERING JOURNAL

X-ray induced photodynamic therapy (PDT) with a mitochondria-targeted liposome delivery system

(2020) Xuefan Gu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Fluorinated peptide biomaterials

(2020) Janna N. Sloand et al.   Peptide Science

Au2Pt-PEG-Ce6 nanoformulation with dual nanozyme activities for synergistic chemodynamic therapy / phototherapy

(2020) Man Wang et al.   BIOMATERIALS

Dual‐Targeting Photosensitizer‐Peptide Amphiphile Conjugate for Enzyme‐Triggered Drug Delivery and Synergistic Chemo‐Photodynamic Tumor Therapy

(2020) Yin‐Jia Cheng et al.   Advanced Materials Interfaces

Bright Aggregation-Induced Emission Nanoparticles for Two-Photon Imaging and Localized Compound Therapy of Cancers

(2020) Ying Li et al.   ACS Nano

The role of hypoxia‐inducible factor 1 in tumor immune evasion

(2020) Li You et al.   MEDICINAL RESEARCH REVIEWS

Perfluorocarbon-Loaded and Redox-Activatable Photosensitizing Agent with Oxygen Supply for Enhancement of Fluorescence/Photoacoustic Imaging Guided Tumor Photodynamic Therapy

(2019) DanRong Hu et al.   ADVANCED FUNCTIONAL MATERIALS

AIE Multinuclear Ir(III) Complexes for Biocompatible Organic Nanoparticles with Highly Enhanced Photodynamic Performance

(2019) Liping Zhang et al.   Advanced Science

Titanium-Based Nanoscale Metal–Organic Framework for Type I Photodynamic Therapy

(2019) Guangxu Lan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy

(2019) Weijing Yang et al.   ACS Nano

Organic Photodynamic Nanoinhibitor for Synergistic Cancer Therapy

(2019) Yuyan Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intelligent Hollow Pt-CuS Janus Architecture for Synergistic Catalysis-Enhanced Sonodynamic and Photothermal Cancer Therapy

(2019) Shuang Liang et al.   NANO LETTERS

Improvement of Photostability and NIR Activity of Cyanine Dye through Nanohybrid Formation: Key Information from Ultrafast Dynamical Studies

(2019) Arpan Bera et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Overcoming the Reticuloendothelial System Barrier to Drug Delivery with a “Don’t-Eat-Us” Strategy

(2019) Yixuan Tang et al.   ACS Nano

Oxygen-Self-Supplying and HIF-1α-Inhibiting Core–Shell Nanosystem for Hypoxia-Resistant Photodynamic Therapy

(2019) Peng Liu et al.   ACS Applied Materials & Interfaces

Boosting the photodynamic therapy efficiency by using stimuli-responsive and AIE-featured nanoparticles

(2019) Youmei Li et al.   BIOMATERIALS

Light-Activatable Red Blood Cell Membrane-Camouflaged Dimeric Prodrug Nanoparticles for Synergistic Photodynamic/Chemotherapy

(2018) Qing Pei et al.   ACS Nano

Innovative Strategies for Hypoxic-Tumor Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photodynamic therapy – mechanisms, photosensitizers and combinations

(2018) Stanisław Kwiatkowski et al.   BIOMEDICINE & PHARMACOTHERAPY

Hypoxia induced EMT: A review on the mechanism of tumor progression and metastasis in OSCC

(2018) Joel P. Joseph et al.   ORAL ONCOLOGY

Red-emissive azabenzanthrone derivatives for photodynamic therapy irradiated with ultralow light power density and two-photon imaging

(2018) Qiguang Zang et al.   Chemical Science

Rational design of a water-soluble NIR AIEgen, and its application in ultrafast wash-free cellular imaging and photodynamic cancer cell ablation

(2018) Dong Wang et al.   Chemical Science

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

(2018) Gantumur Battogtokh et al.   Acta Pharmaceutica Sinica B

PEGylated Multi-Stimuli Responsive Dendritic Prodrug-Based Nanoscale System for Enhanced Anticancer Activity

(2018) Zhenyu Duan et al.   ACS Applied Materials & Interfaces

Mitochondria and plasma membrane dual-targeted chimeric peptide for single-agent synergistic photodynamic therapy

(2018) Hong Cheng et al.   BIOMATERIALS

Enhanced Photodynamic Cancer Treatment by Mitochondria-Targeting and Brominated Near-Infrared Fluorophores

(2017) Ilkoo Noh et al.   Advanced Science

Perfluorocarbon-Loaded Hollow Bi2Se3Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer

(2016) Guosheng Song et al.   ADVANCED MATERIALS

Fasting protects against the side effects of irinotecan treatment but does not affect anti-tumour activity in mice

(2016) Sander A Huisman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Two-photon excitation nanoparticles for photodynamic therapy

(2016) Yizhong Shen et al.   CHEMICAL SOCIETY REVIEWS

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

(2016) Zijian Zhou et al.   CHEMICAL SOCIETY REVIEWS

Beyond the Barriers of Light Penetration: Strategies, Perspectives and Possibilities for Photodynamic Therapy

(2016) Srivalleesha Mallidi et al.   Theranostics

Dual-Stage-Light-Guided Tumor Inhibition by Mitochondria-Targeted Photodynamic Therapy

(2015) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy

(2014) Zonghai Sheng et al.   ACS Nano

Surface Charge Switchable Nanoparticles Based on Zwitterionic Polymer for Enhanced Drug Delivery to Tumor

(2012) You-Yong Yuan et al.   ADVANCED MATERIALS

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects

(2011) Puja Sapra et al.   ANGIOGENESIS

Tumor Regression and Curability of Preclinical Neuroblastoma Models by PEGylated SN38 (EZN-2208), a Novel Topoisomerase I Inhibitor

(2010) F. Pastorino et al.   CLINICAL CANCER RESEARCH

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY