Loureirin B protects against obesity via activation of adipose tissue ω3 PUFA-GPR120-UCP1 axis in mice

Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

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Optineurin promotes myogenesis during muscle regeneration in mice by autophagic degradation of GSK3β

(2022) Xiao Chen Shi et al.   PLOS BIOLOGY

Human Cytomegalovirus Uses a Host Stress Response To Balance the Elongation of Saturated/Monounsaturated and Polyunsaturated Very-Long-Chain Fatty Acids

(2021) Yuecheng Xi et al.   mBio

Identification of Dacinostat as a potential anti-obesity compound through transcriptional activation of adipose thermogenesis in mice

(2021) Xin Yi Chu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

(2020) Farnaz Shamsi et al.   Nature Communications

Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT

(2020) Hiroyasu Sato et al.   Cell Reports

Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice

(2020) Bo Xia et al.   PLOS BIOLOGY

Phenolic constituents, pharmacological activities, quality control, and metabolism of Dracaena species: A review

(2019) Jing Sun et al.   JOURNAL OF ETHNOPHARMACOLOGY

Adaptive thermogenesis by dietary n-3 polyunsaturated fatty acids: Emerging evidence and mechanisms

(2018) Rong Fan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

(2018) Maaike Schilperoort et al.   EMBO Molecular Medicine

New Advances in Adaptive Thermogenesis: UCP1 and Beyond

(2018) Edward T. Chouchani et al.   Cell Metabolism

Loureirin B promotes axon regeneration by inhibiting ER stress-induced mitochondrial dysfunction and regulating the Akt/GSK-3β pathway after spinal cord injury

(2018) Qingqing Wang et al.   JOURNAL OF NEUROTRAUMA

α-lipoic acid ameliorates n-3 highly-unsaturated fatty acids induced lipid peroxidation via regulating antioxidant defenses in grass carp ( Ctenopharyngodon idellus )

(2017) Xiao-chen Shi et al.   FISH & SHELLFISH IMMUNOLOGY

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

(2017) Nathalia R. V. Dragano et al.   Journal of Neuroinflammation

Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease

(2017) Matthias J. Betz et al.   Nature Reviews Endocrinology

Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1 + Adipocytes

(2016) Hong Wang et al.   Cell Metabolism

Epidemiology of Obesity and Diabetes and Their Cardiovascular Complications

(2016) Shilpa N. Bhupathiraju et al.   CIRCULATION RESEARCH

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

(2016) Tania Quesada-López et al.   Nature Communications

Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment

(2015) Jinhai Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Treatment of Obesity with Celastrol

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Lipolysis and lipases in white adipose tissue – An update

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Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with Δ9-Tetrahydrocannabinol

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Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice

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A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice

(2014) Da Young Oh et al.   NATURE MEDICINE

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

(2012) Atsuhiko Ichimura et al.   NATURE

Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation

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Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration

(2011) S. Gesta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

(2011) Saswata Talukdar et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Nonshivering thermogenesis and its adequate measurement in metabolic studies

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