Pharmacokinetics of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase 1, Open-Label Study of Healthy Adults

Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes

(2022) Stephen J Balevic et al.   Lupus Science & Medicine

Safety of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase I, Open-Label Study in Healthy Adult Volunteers

(2022) Thomas P. Lodise et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy of ceftazidime-avibactam plus aztreonam in patients with bloodstream infections caused by MBL- producing Enterobacterales

(2020) Marco Falcone et al.   CLINICAL INFECTIOUS DISEASES

Determining the optimal dosing of a novel combination regimen of ceftazidime/avibactam with aztreonam against NDM-1-producing Enterobacteriaceae using a hollow-fibre infection model

(2020) Thomas P Lodise et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Pharmacodynamic-Toxicodynamic Relationship of AUC and CMAX in Vancomycin Induced Kidney Injury in an Animal Model

(2020) Sean N. Avedissian et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Considerations for Dose Selection and Clinical Pharmacokinetics/Pharmacodynamics for the Development of Antibacterial Agents

(2019) M.L. Rizk et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intermittent vs. continuous vancomycin infusion for gram-positive infections: A systematic review and meta-analysis

(2019) Yang Chu et al.   Journal of Infection and Public Health

Ceftazidime-Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

(2018) Jianguo Li et al.   CTS-Clinical and Translational Science

Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future

(2018) Paul W. Smith et al.   ACS Infectious Diseases

Clinical outcomes after combination treatment with ceftazidime/avibactam and aztreonam for NDM-1/OXA-48/CTX-M-15-producing Klebsiella pneumoniae infection

(2017) Evelyn Shaw et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Successful Treatment of Bloodstream Infection Due to Metallo-β-Lactamase-Producing Stenotrophomonas maltophilia in a Renal Transplant Patient

(2016) Maria F. Mojica et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of Aztreonam Dosing Regimens in Patients With Normal and Impaired Renal Function: A Population Pharmacokinetic Modeling and Monte Carlo Simulation Analysis

(2016) Hongmei Xu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The global epidemiology of carbapenemase-producing Enterobacteriaceae

(2016) David van Duin et al.   Virulence

Evaluation of Daptomycin Exposure and Efficacy and Safety Endpoints To Support Risk-versus-Benefit Considerations

(2015) Sujata M. Bhavnani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multiyear, Multinational Survey of the Incidence and Global Distribution of Metallo-β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa

(2015) Krystyna M. Kazmierczak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Avibactam Alone and in Combination with Ceftazidime in Healthy Male Volunteers: Results of Two Randomized, Placebo-Controlled Studies

(2015) Henri Merdjan et al.   CLINICAL DRUG INVESTIGATION

Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam

(2015) Renu Singh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens

(2015) David P. Nicolau et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications

(2015) Lily Dara et al.   LIVER INTERNATIONAL

Nonclinical and Pharmacokinetic Assessments To Evaluate the Potential of Tedizolid and Linezolid To Affect Mitochondrial Function

(2014) Shawn Flanagan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dual beta-lactam therapy for serious Gram-negative infections: is it time to revisit?

(2014) Christine Rahme et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Methodology to Assess Clinical Liver Safety Data

(2014) Michael Merz et al.   DRUG SAFETY

Liver Safety Assessment: Required Data Elements and Best Practices for Data Collection and Standardization in Clinical Trials

(2014) Mark I. Avigan et al.   DRUG SAFETY

Comparison of Methods for Handling Missing Covariate Data

(2013) Åsa M. Johansson et al.   AAPS Journal

Continuous versus Conventional Infusion of Amphotericin B Deoxycholate: A Meta-Analysis

(2013) Matthew E. Falagas et al.   PLoS One

Continuous versus intermittent infusion of vancomycin for the treatment of Gram-positive infections: systematic review and meta-analysis

(2011) M. A. Cataldo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis

(2010) Sujata M. Bhavnani et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetic‐Pharmacodynamic Considerations in the Design of Hospital‐Acquired or Ventilator‐Associated Bacterial Pneumonia Studies: Look before You Leap!

(2010) Paul G. Ambrose et al.   CLINICAL INFECTIOUS DISEASES

Daptomycin: From the Mountain to the Clinic, with Essential Help from Francis Tally, MD

(2010) Barry I. Eisenstein et al.   CLINICAL INFECTIOUS DISEASES

Handling Data Below the Limit of Quantification in Mixed Effect Models

(2009) Martin Bergstrand et al.   AAPS Journal

Racial and Ethnic Differences in Presentation, Etiology, and Outcomes of Acute Liver Failure in the United States

(2009) Kimberly A. Forde et al.   Clinical Gastroenterology and Hepatology