Interactions between inflammatory mediators and corticosteroids regulate transcription of genes within the Kynurenine Pathway in the mouse hippocampus

L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences

(2017) Hidetsugu Fujigaki et al.   NEUROPHARMACOLOGY

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice

(2015) Michelle S. Antunes et al.   HORMONES AND BEHAVIOR

Trends in Prescription Drug Use Among Adults in the United States From 1999-2012

(2015) Elizabeth D. Kantor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation

(2014) Richard Metz et al.   INTERNATIONAL IMMUNOLOGY

Characterization of Functional Polymorphisms and Glucocorticoid-Responsive Elements in the Promoter of TDO2, a Candidate Gene for Ethanol-Induced Behavioural Disorders

(2013) Marion Soichot et al.   ALCOHOL AND ALCOHOLISM

Swimming exercise ameliorates depression-like behavior in chronically stressed rats: Relevant to proinflammatory cytokines and IDO activation

(2013) Weina Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease

(2013) Gelareh Mazarei et al.   JOURNAL OF NEUROCHEMISTRY

Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

(2013) Marcus A Lawson et al.   Journal of Neuroinflammation

Insulin Resistance and Dysregulation of Tryptophan–Kynurenine and Kynurenine–Nicotinamide Adenine Dinucleotide Metabolic Pathways

(2013) Gregory Oxenkrug   MOLECULAR NEUROBIOLOGY

Quinolinic acid, the inescapable neurotoxin

(2012) Gilles J. Guillemin   FEBS Journal

Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2

(2012) Masakazu Fukunaga et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Depression: an inflammatory illness?: Figure 1

(2012) Rajeev Krishnadas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder

(2012) Jessica A Cutler et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Single nucleotide polymorphisms of NR3C1 gene and recurrent depressive disorder in population of Poland

(2012) Elżbieta Gałecka et al.   MOLECULAR BIOLOGY REPORTS

The Stat3/GR Interaction Code: Predictive Value of Direct/Indirect DNA Recruitment for Transcription Outcome

(2012) David Langlais et al.   MOLECULAR CELL

Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: Effects of stress

(2012) C.A. Browne et al.   NEUROSCIENCE

Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia

(2011) Yingqian Huo et al.   BMC NEUROSCIENCE

Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder

(2011) Aleksandra Szczepankiewicz et al.   JOURNAL OF AFFECTIVE DISORDERS

HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner

(2011) Xin Fu et al.   Journal of Neuroinflammation

Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice

(2011) Sook-Eun Park et al.   Journal of Neuroinflammation

Association of a polymorphism in the indoleamine- 2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C

(2011) A K Smith et al.   MOLECULAR PSYCHIATRY

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)

(2011) Juliana Croitoru-Lamoury et al.   PLoS One

Is Depression an Inflammatory Disorder?

(2011) Charles L. Raison et al.   Current Psychiatry Reports

Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2

(2010) Christopher Jonathan Daraius Austin et al.   AMINO ACIDS

Linking the cytokine and neurocircuitry hypotheses of depression: A translational framework for discovery and development of novel anti-depressants

(2010) Timothy M. Piser   BRAIN BEHAVIOR AND IMMUNITY

Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders

(2010) Gregory F. Oxenkrug   JOURNAL OF NEURAL TRANSMISSION

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

(2010) Xin Fu et al.   Journal of Neuroinflammation

Outcome of psychiatric symptoms presenting at onset of multiple sclerosis: a retrospective study

(2010) Salvatore Lo Fermo et al.   Multiple Sclerosis Journal

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene: Differential regulation in the mouse nervous system during development

(2009) Masaaki Kanai et al.   NEUROSCIENCE RESEARCH

Mouse and human indoleamine 2,3-dioxygenase display some distinct biochemical and structural properties

(2008) Christopher J. D. Austin et al.   AMINO ACIDS

Activation of Central Nervous System Inflammatory Pathways by Interferon-Alpha: Relationship to Monoamines and Depression

(2008) Charles L. Raison et al.   BIOLOGICAL PSYCHIATRY

Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior

(2008) Maïté Moreau et al.   BRAIN BEHAVIOR AND IMMUNITY

Kynurenine pathway metabolism in human blood–brain–barrier cells: implications for immune tolerance & neurotoxicity

(2008) Robert Owe-Young et al.   JOURNAL OF NEUROCHEMISTRY

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Interferon-?? Low Producer Genotype +874 Overrepresented in Bacillus Calmette-Guerin Nonresponding Children

(2008) Bandaru Anuradha et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL