Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination

(2015) Shweta S. Puntambekar et al.   GLIA

Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis

(2015) Carine Savarin et al.   Journal of Neuroinflammation

Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS)

(2015) Tina KhorshidAhmad et al.   MOLECULAR NEUROBIOLOGY

PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

(2014) Parul Kapil et al.   JOURNAL OF NEUROIMMUNOLOGY

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

TNF-α/TNFR1 Signaling Is Required for the Development and Function of Primary Nociceptors

(2014) Michael A. Wheeler et al.   NEURON

Blockade of tumour necrosis factor-α in experimental autoimmune encephalomyelitis reveals differential effects on the antigen-specific immune response and central nervous system histopathology

(2013) H. Batoulis et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Elevation of Tumor Necrosis Factor Alpha in Dorsal Root Ganglia and Spinal Cord is Associated with Neuroimmune Modulation of Pain in an Animal Model of Multiple Sclerosis

(2013) F. Begum et al.   Journal of Neuroimmune Pharmacology

Persistent Inflammation in the CNS during Chronic EAE Despite Local Absence of IL-17 Production

(2013) Sofia Fernanda Gonçalves Zorzella-Pezavento et al.   MEDIATORS OF INFLAMMATION

LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner

(2012) Aedín M Minogue et al.   Journal of Neuroinflammation

IFN-γ Signaling to Astrocytes Protects from Autoimmune Mediated Neurological Disability

(2012) Claudia Hindinger et al.   PLoS One

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

How do immune cells overcome the blood-brain barrier in multiple sclerosis?

(2011) Catherine Larochelle et al.   FEBS LETTERS

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

TGF-  Enhances Effector Th1 Cell Activation but Promotes Self-Regulation via IL-10

(2010) D. J. Huss et al.   JOURNAL OF IMMUNOLOGY

Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells

(2010) Tsuyoshi Nishioku et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Tumour necrosis factor-α affects blood-brain barrier permeability and tight junction-associated occludin in acute liver failure

(2010) Sa Lv et al.   LIVER INTERNATIONAL

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia

(2009) M. Melanson et al.   Multiple Sclerosis Journal

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes

(2008) Jacques Thibodeau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

(2008) Satoshi Serada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Necrosis Factor α Regulates Responses to Nerve Growth Factor, Promoting Neural Cell Survival but Suppressing Differentiation of Neuroblastoma Cells

(2007) Yoshinori Takei et al.   MOLECULAR BIOLOGY OF THE CELL