Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1G93A mice model of ALS
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chronic administration of AMD3100 increases survival and alleviates pathology in SOD1G93A mice model of ALS
Authors
Keywords
Microglia, Blood-spinal cord barrier, AMD3100, ALS, SOD1<sup>G93A</sup> mice, Hematopoietic stem and progenitor cells, CXCR4/CXCL12
Journal
Journal of Neuroinflammation
Volume 13, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-05-26
DOI
10.1186/s12974-016-0587-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Comparative study of behavioural tests in the SOD1G93A mouse model of amyotrophic lateral sclerosis
- (2015) Sara OLIVÁN et al. EXPERIMENTAL ANIMALS
- Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke
- (2015) Helene L Walter et al. Journal of Neuroinflammation
- Prenatal stress is a vulnerability factor for altered morphology and biological activity of microglia cells
- (2015) Joanna Ślusarczyk et al. Frontiers in Cellular Neuroscience
- Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice
- (2014) E. A. Winkler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microglia centered pathogenesis in ALS: insights in cell interconnectivity
- (2014) Dora Brites et al. Frontiers in Cellular Neuroscience
- Plastic Changes in the Spinal Cord in Motor Neuron Disease
- (2014) Francesco Fornai et al. Biomed Research International
- Neural stem cells in the adult spinal cord
- (2013) Hanna Sabelström et al. EXPERIMENTAL NEUROLOGY
- Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats
- (2013) Maria Nikodemova et al. NEUROBIOLOGY OF DISEASE
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
- (2012) Ethan A. Winkler et al. ACTA NEUROPATHOLOGICA
- Impaired blood–brain/spinal cord barrier in ALS patients
- (2012) Svitlana Garbuzova-Davis et al. BRAIN RESEARCH
- Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype
- (2012) Kate Roberts et al. GLIA
- Role of SDF1/CXCR4 Interaction in Experimental Hemiplegic Models with Neural Cell Transplantation
- (2012) Nagisa Arimitsu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CXCR4 Antagonist AMD3100 Protects Blood–Brain Barrier Integrity and Reduces Inflammatory Response After Focal Ischemia in Mice
- (2012) Jun Huang et al. STROKE
- The Role of Immune and Inflammatory Mechanisms in ALS
- (2011) P. A. McCombe et al. CURRENT MOLECULAR MEDICINE
- Combined Effects of Hematopoietic Progenitor Cell Mobilization from Bone Marrow by Granulocyte Colony Stimulating Factor and AMD3100 and Chemotaxis into the Brain Using Stromal Cell-Derived Factor-1α in an Alzheimer's Disease Mouse Model
- (2011) Ji-Woong Shin et al. STEM CELLS
- Mesenchymal stem cell transplantation modulates neuroinflammation in focal cerebral ischemia: Contribution of fractalkine and IL-5
- (2010) Abdullah Md. Sheikh et al. NEUROBIOLOGY OF DISEASE
- Mesenchymal Lineage Stem Cells Have Pronounced Anti-Inflammatory Effects in the Twitcher Mouse Model of Krabbe's Disease
- (2010) Cynthia B. Ripoll et al. STEM CELLS
- The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil)
- (2009) Erik De Clercq BIOCHEMICAL PHARMACOLOGY
- Monocyte Chemoattractant Protein-1 (MCP-1): An Overview
- (2009) Satish L. Deshmane et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
- (2009) Cameron R Stewart et al. NATURE IMMUNOLOGY
- DECREASED mRNA EXPRESSION OF TIGHT JUNCTION PROTEINS IN LUMBAR SPINAL CORDS OF PATIENTS WITH ALS
- (2009) J. S. Henkel et al. NEUROLOGY
- Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF- B pathways and promotes osteoclastogenesis in human oral cancer cells
- (2008) C.-H. Tang et al. CARCINOGENESIS
- Neuroprotective effects of human mesenchymal stem cells on dopaminergic neurons through anti-inflammatory action
- (2008) You-Joung Kim et al. GLIA
- ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
- (2008) Zhihui Zhong et al. NATURE NEUROSCIENCE
- Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis
- (2008) A. Vercelli et al. NEUROBIOLOGY OF DISEASE
- Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses
- (2008) H. Ohtaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started