Anti-Inflammatory and Neuroprotective Effects of PGE2 EP4 Signaling in Models of Parkinson’s Disease

Protection by vascular prostaglandin E2 signaling in hypoxic–ischemic encephalopathy

(2014) Hidetoshi Taniguchi et al.   EXPERIMENTAL NEUROLOGY

Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling

(2014) N. S. Woodling et al.   JOURNAL OF NEUROSCIENCE

Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia

(2013) J. U. Johansson et al.   JOURNAL OF NEUROSCIENCE

Commentary: Progressive inflammation as a contributing factor to early development of Parkinson's disease

(2012) Suraj Pradhan et al.   EXPERIMENTAL NEUROLOGY

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia

(2012) Lisa Fellner et al.   GLIA

Signaling via the prostaglandin E2 receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia

(2011) Xibin Liang et al.   JOURNAL OF CLINICAL INVESTIGATION

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Function of prostaglandin E2 EP receptors in the acute outcome of rodent hypoxic ischemic encephalopathy

(2011) Hidetoshi Taniguchi et al.   NEUROSCIENCE LETTERS

The Prostaglandin E2 E-Prostanoid 4 Receptor Exerts Anti-Inflammatory Effects in Brain Innate Immunity

(2010) J. Shi et al.   JOURNAL OF IMMUNOLOGY

Paroxetine Prevents Loss of Nigrostriatal Dopaminergic Neurons by Inhibiting Brain Inflammation and Oxidative Stress in an Experimental Model of Parkinson's Disease

(2010) Y. C. Chung et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons

(2010) Guy C. Brown et al.   MOLECULAR NEUROBIOLOGY

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

Emerging roles of PGE2 receptors in models of neurological disease

(2009) Katrin Andreasson   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The prostaglandin E2EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis

(2008) Xibin Liang et al.   ANNALS OF NEUROLOGY

Non-autonomous cell death in Parkinson's disease

(2008) Ted M Dawson   LANCET NEUROLOGY

Synuclein activates microglia in a model of Parkinson's disease

(2007) Xiaomin Su et al.   NEUROBIOLOGY OF AGING

α-Synuclein activates stress signaling protein kinases in THP-1 cells and microglia

(2006) Andis Klegeris et al.   NEUROBIOLOGY OF AGING