Ion channels as insecticide targets

A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor confers resistance to spinosad in Drosophila melanogaster

(2016) Christoph T. Zimmer et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mutation (G275E) of the nicotinic acetylcholine receptor α6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)

(2016) Wellington M. Silva et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Expression of insect α6-like nicotinic acetylcholine receptors in Drosophila melanogaster highlights a high level of conservation of the receptor:spinosyn interaction

(2015) Trent Perry et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

In vivo functional analysis of the Drosophila melanogaster nicotinic acetylcholine receptor Dα6 using the insecticide spinosad

(2015) Jason Somers et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Geographic spread, genetics and functional characteristics of ryanodine receptor based target-site resistance to diamide insecticides in diamondback moth, Plutella xylostella

(2015) Denise Steinbach et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A point mutation in the glutamate-gated chloride channel ofPlutella xylostellais associated with resistance to abamectin

(2015) X. Wang et al.   INSECT MOLECULAR BIOLOGY

Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae

(2015) J. I. Meyers et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The neonicotinoid imidacloprid, and the pyrethroid deltamethrin, are antagonists of the insect Rdl GABA receptor

(2015) Jennina Taylor-Wells et al.   JOURNAL OF NEUROCHEMISTRY

Reduction in mRNA and protein expression of a nicotinic acetylcholine receptor α8 subunit is associated with resistance to imidacloprid in the brown planthopper,Nilaparvata lugens

(2015) Yixi Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Novel GABA receptor pesticide targets

(2015) John E. Casida et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

The global status of insect resistance to neonicotinoid insecticides

(2015) Chris Bass et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Stable expression and functional characterisation of the diamondback moth ryanodine receptor G4946E variant conferring resistance to diamide insecticides

(2015) Bartlomiej J. Troczka et al.   Scientific Reports

A 36-bp deletion in the alpha subunit of glutamate-gated chloride channel contributes to abamectin resistance inPlutella xylostella

(2014) Feng Liu et al.   ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA

The role of Rdl in resistance to phenylpyrazoles in Drosophila melanogaster

(2014) Emily J. Remnant et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular biology of insect sodium channels and pyrethroid resistance

(2014) Ke Dong et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Diamide Insecticide Target Site Specificity in the Heliothis and Musca Ryanodine Receptors Relative to Toxicity

(2014) Suzhen Qi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Spinosad resistance of melon thrips, Thrips palmi, is conferred by G275E mutation in α6 subunit of nicotinic acetylcholine receptor and cytochrome P450 detoxification

(2014) Wen Xue Bao et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Novel mutations and mutation combinations of ryanodine receptor in a chlorantraniliprole resistant population of Plutella xylostella (L.)

(2014) Lei Guo et al.   Scientific Reports

Neuroactive Insecticides: Targets, Selectivity, Resistance, and Secondary Effects

(2013) John E. Casida et al.   Annual Review of Entomology

Identification of a critical region in the Drosophila ryanodine receptor that confers sensitivity to diamide insecticides

(2013) Yong Tao et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel

(2013) Y. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene duplication in the major insecticide target site,Rdl, inDrosophila melanogaster

(2013) Emily J. Remnant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels

(2012) Stuart J Lansdell et al.   BMC NEUROSCIENCE

Insect Ryanodine Receptor: Distinct but Coupled Insecticide Binding Sites for [N-C3H3]Chlorantraniliprole, Flubendiamide, and [3H]Ryanodine

(2012) André K. Isaacs et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The cys-loop ligand-gated ion channel gene family of Tetranychus urticae: Implications for acaricide toxicology and a novel mutation associated with abamectin resistance

(2012) W. Dermauw et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Truncated transcripts of nicotinic acetylcholine subunit gene Bdα6 are associated with spinosad resistance in Bactrocera dorsalis

(2012) Ju-Chun Hsu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Resistance to diamide insecticides in diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae) is associated with a mutation in the membrane-spanning domain of the ryanodine receptor

(2012) Bartek Troczka et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Glutamate-gated Chloride Channels

(2012) Adrian J. Wolstenholme   JOURNAL OF BIOLOGICAL CHEMISTRY

High Levels of Resistance to Chlorantraniliprole Evolved in Field Populations of Plutella xylostella

(2012) Xingliang Wang et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

A nicotinic acetylcholine receptor transmembrane point mutation (G275E) associated with resistance to spinosad inFrankliniella occidentalis

(2012) Alin M. Puinean et al.   JOURNAL OF NEUROCHEMISTRY

Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae

(2011) Chris Bass et al.   BMC NEUROSCIENCE

The A2′N Mutation of the RDL γ-Aminobutyric Acid Receptor Conferring Fipronil Resistance in Laodelphax striatellus (Hemiptera: Delphacidae)

(2011) Toshifumi Nakao et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Identifying the presence of neonicotinoidresistant peach-potato aphid (Myzus persicae) in the peach-growing regions of southern France and northern Spain

(2011) Russell Slater et al.   PEST MANAGEMENT SCIENCE

Effects of mutations in Drosophila nicotinic acetylcholine receptor subunits on sensitivity to insecticides targeting nicotinic acetylcholine receptors

(2011) Trent Perry et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

A point mutation in a glutamate-gated chloride channel confers abamectin resistance in the two-spotted spider mite, Tetranychus urticae Koch

(2010) D. H. Kwon et al.   INSECT MOLECULAR BIOLOGY

Transcripts of the nicotinic acetylcholine receptor subunit gene Pxylα6 with premature stop codons are associated with spinosad resistance in diamondback moth, Plutella xylostella

(2010) Frank D. Rinkevich et al.   INVERTEBRATE NEUROSCIENCE

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

Mis-Spliced Transcripts of Nicotinic Acetylcholine Receptor α6 Are Associated with Field Evolved Spinosad Resistance in Plutella xylostella (L.)

(2010) Simon W. Baxter et al.   PLoS Genetics

Molecular Characterization of Flubendiamide Sensitivity in the Lepidopterous Ryanodine Receptor Ca2+Release Channel

(2009) Kenta Kato et al.   BIOCHEMISTRY

Native subunit composition of two insect nicotinic receptor subtypes with differing affinities for the insecticide imidacloprid

(2009) Jian Li et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A spinosyn-sensitive Drosophila melanogaster nicotinic acetylcholine receptor identified through chemically induced target site resistance, resistance gene identification, and heterologous expression

(2009) Gerald B. Watson et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Alternative Splicing in the Voltage-Gated Sodium Channel DmNav Regulates Activation, Inactivation, and Persistent Current

(2009) Wei-Hsiang Lin et al.   JOURNAL OF NEUROPHYSIOLOGY

Splice-Variant- and Stage-Specific RNA Editing of the Drosophila GABA Receptor Modulates Agonist Potency

(2009) A. K. Jones et al.   JOURNAL OF NEUROSCIENCE

The ligand-gated chloride channel gene family of Drosophila melanogaster

(2009) Douglas C. Knipple et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Mutations in Dα1 or Dβ2 nicotinic acetylcholine receptor subunits can confer resistance to neonicotinoids in Drosophila melanogaster

(2008) Trent Perry et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Molecular and functional characterization of voltage-gated sodium channel variants from Drosophila melanogaster

(2008) Rachel O’Donnell Olson et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Insect ryanodine receptors: molecular targets for novel pest control chemicals

(2008) David B. Sattelle et al.   INVERTEBRATE NEUROSCIENCE

Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling

(2008) TG Emyr Davies et al.   PEST MANAGEMENT SCIENCE