Reward from bugs to bipeds: a comparative approach to understanding how reward circuits function

Neuropeptide Y in noradrenergic neurons induces obesity in transgenic mouse models

(2016) Laura H. Vähätalo et al.   NEUROPEPTIDES

The corticotropin-releasing factor-like diuretic hormone 44 (DH 44 ) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster

(2016) Elizabeth Cannell et al.   PEPTIDES

Serotonin controlling feeding and satiety

(2015) Jörg-Peter Voigt et al.   BEHAVIOURAL BRAIN RESEARCH

Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala

(2015) J. Wood et al.   Brain Structure & Function

Sleep Facilitates Memory by Blocking Dopamine Neuron-Mediated Forgetting

(2015) Jacob A. Berry et al.   CELL

Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila

(2015) Raphael Cohn et al.   CELL

A Higher Brain Circuit for Immediate Integration of Conflicting Sensory Information in Drosophila

(2015) Laurence P.C. Lewis et al.   CURRENT BIOLOGY

Genealogical Correspondence of Mushroom Bodies across Invertebrate Phyla

(2015) Gabriella H. Wolff et al.   CURRENT BIOLOGY

A Subset of Serotonergic Neurons Evokes Hunger in Adult Drosophila

(2015) Stephanie D. Albin et al.   CURRENT BIOLOGY

Sweet Taste and Nutrient Value Subdivide Rewarding Dopaminergic Neurons in Drosophila

(2015) Wolf Huetteroth et al.   CURRENT BIOLOGY

Neuropeptide F neurons modulate sugar reward during associative olfactory learning ofDrosophilalarvae

(2015) Astrid Rohwedder et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuronal polarity: an evolutionary perspective

(2015) M. M. Rolls et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Norepinephrine Activates Dopamine D4 Receptors in the Rat Lateral Habenula

(2015) D. H. Root et al.   JOURNAL OF NEUROSCIENCE

Viral-genetic tracing of the input–output organization of a central noradrenaline circuit

(2015) Lindsay A. Schwarz et al.   NATURE

Plasticity-driven individualization of olfactory coding in mushroom body output neurons

(2015) Toshihide Hige et al.   NATURE

Striatal D1 and D2 signaling differentially predict learning from positive and negative outcomes

(2015) Sylvia M.L. Cox et al.   NEUROIMAGE

Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila

(2015) David Owald et al.   NEURON

Neurotransmitter Switching? No Surprise

(2015) Nicholas C. Spitzer   NEURON

Cre-driven optogenetics in the heterogeneous genetic panorama of the VTA

(2015) Stéfano Pupe et al.   TRENDS IN NEUROSCIENCES

Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis

(2015) Ana Aransay et al.   Frontiers in Neuroanatomy

An opioid-like system regulating feeding behavior in C. elegans

(2015) Mi Cheong Cheong et al.   eLife

A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster

(2015) Paula R Haynes et al.   eLife

Reward signal in a recurrent circuit drives appetitive long-term memory formation

(2015) Toshiharu Ichinose et al.   eLife

A cholinergic feedback circuit to regulate striatal population uncertainty and optimize reinforcement learning

(2015) Nicholas T Franklin et al.   eLife

Toward elucidating diversity of neural mechanisms underlying insect learning

(2015) Makoto Mizunami et al.   Zoological Letters

The role of the laterodorsal tegmental nucleus in methamphetamine conditioned place preference and locomotor activity

(2014) Lauren K. Dobbs et al.   BEHAVIOURAL BRAIN RESEARCH

Dopaminergic Modulation of cAMP Drives Nonlinear Plasticity across the Drosophila Mushroom Body Lobes

(2014) Tamara Boto et al.   CURRENT BIOLOGY

Rewarding, reinforcing and incentive salient events involve orexigenic hypothalamic neuropeptides regulating mesolimbic dopaminergic neurotransmission

(2014) Davide Quarta et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Ghrelin Acts as an Interface between Physiological State and Phasic Dopamine Signaling

(2014) J. J. Cone et al.   JOURNAL OF NEUROSCIENCE

Role of Glutamatergic Projections from Ventral Tegmental Area to Lateral Habenula in Aversive Conditioning

(2014) D. H. Root et al.   JOURNAL OF NEUROSCIENCE

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Critical role of cholinergic transmission from the laterodorsal tegmental nucleus to the ventral tegmental area in cocaine-induced place preference

(2014) Fumiya Shinohara et al.   NEUROPHARMACOLOGY

Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors

(2014) S. Nakanishi et al.   NEUROSCIENCE

Distribution of VGLUT3 in Highly Collateralized Axons from the Rat Dorsal Raphe Nucleus as Revealed by Single-Neuron Reconstructions

(2014) Dave Gagnon et al.   PLoS One

Serotonergic versus Nonserotonergic Dorsal Raphe Projection Neurons: Differential Participation in Reward Circuitry

(2014) Ross A. McDevitt et al.   Cell Reports

Genetic Approaches to Neural Circuits in the Mouse

(2013) Z. Josh Huang et al.   Annual Review of Neuroscience

An Octopamine-Mushroom Body Circuit Modulates the Formation of Anesthesia-Resistant Memory in Drosophila

(2013) Chia-Lin Wu et al.   CURRENT BIOLOGY

The long and short of GABAergic neurons

(2013) Antonio Caputi et al.   CURRENT OPINION IN NEUROBIOLOGY

Reinforcement signalling in Drosophila; dopamine does it all after all

(2013) Scott Waddell   CURRENT OPINION IN NEUROBIOLOGY

Distinct extended amygdala circuits for divergent motivational states

(2013) Joshua H. Jennings et al.   NATURE

Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids

(2013) Gwenaël Labouèbe et al.   NATURE NEUROSCIENCE

Differential role of ventral tegmental area acetylcholine and N-methyl-d-aspartate receptors in cocaine-seeking

(2013) Wojciech Solecki et al.   NEUROPHARMACOLOGY

Octopamine-mediated circuit mechanism underlying controlled appetite for palatable food in Drosophila

(2013) T. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep Homology of Arthropod Central Complex and Vertebrate Basal Ganglia

(2013) N. J. Strausfeld et al.   SCIENCE

Dissecting the diversity of midbrain dopamine neurons

(2013) Jochen Roeper   TRENDS IN NEUROSCIENCES

Two Pairs of Mushroom Body Efferent Neurons Are Required for Appetitive Long-Term Memory Retrieval in Drosophila

(2013) Pierre-Yves Plaçais et al.   Cell Reports

Neuropeptide-Gated Perception of Appetitive Olfactory Inputs in Drosophila Larvae

(2013) Yonghua Wang et al.   Cell Reports

Neural Mechanisms of Reward in Insects

(2012) Clint J. Perry et al.   Annual Review of Entomology

Neuropeptide Y Stimulates Food Intake in the Zebrafish, Danio rerio

(2012) E. Yokobori et al.   JOURNAL OF NEUROENDOCRINOLOGY

Serotonin is Critical for Rewarded Olfactory Short-Term Memory in Drosophila

(2012) Divya Sitaraman et al.   JOURNAL OF NEUROGENETICS

Opposite actions of dopamine on aversive and appetitive memories in the crab

(2012) M. Klappenbach et al.   LEARNING & MEMORY

A subset of dopamine neurons signals reward for odour memory in Drosophila

(2012) Chang Liu et al.   NATURE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Layered reward signalling through octopamine and dopamine in Drosophila

(2012) Christopher J. Burke et al.   NATURE

Distinct roles for direct and indirect pathway striatal neurons in reinforcement

(2012) Alexxai V Kravitz et al.   NATURE NEUROSCIENCE

Activation of VTA GABA Neurons Disrupts Reward Consumption

(2012) Ruud van Zessen et al.   NEURON

GABA Neurons of the VTA Drive Conditioned Place Aversion

(2012) Kelly R. Tan et al.   NEURON

Neuropeptide Y (NPY) in the extended amygdala is recruited during the transition to alcohol dependence

(2012) Nicholas W. Gilpin   NEUROPEPTIDES

Activation of alpha1-adrenoceptors enhances glutamate release onto ventral tegmental area dopamine cells

(2012) M.C. Velásquez-Martinez et al.   NEUROSCIENCE

Identification of Rat Ventral Tegmental Area GABAergic Neurons

(2012) Elyssa B. Margolis et al.   PLoS One

Pathway-specific control of reward learning and its flexibility via selective dopamine receptors in the nucleus accumbens

(2012) S. Yawata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexual Deprivation Increases Ethanol Intake in Drosophila

(2012) G. Shohat-Ophir et al.   SCIENCE

Three Dopamine Pathways Induce Aversive Odor Memories with Different Stability

(2012) Yoshinori Aso et al.   PLoS Genetics

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Are mushroom bodies cerebellum-like structures?

(2011) Sarah M. Farris   ARTHROPOD STRUCTURE & DEVELOPMENT

Dissecting mechanisms of reconsolidation: octopamine reveals differences between appetitive and aversive memories in the crab Chasmagnathus

(2011) Laura Kaczer et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Power tools for gene expression and clonal analysis in Drosophila

(2011) Alberto del Valle Rodríguez et al.   NATURE METHODS

Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila

(2011) Julien Séjourné et al.   NATURE NEUROSCIENCE

Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly

(2011) Koen J.T. Venken et al.   NEURON

Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli

(2011) Stephan Lammel et al.   NEURON

Serotonin receptor activity is necessary for olfactory learning and memory in Drosophila melanogaster

(2011) O. Johnson et al.   NEUROSCIENCE

5-HT2C Receptors Localize to Dopamine and GABA Neurons in the Rat Mesoaccumbens Pathway

(2011) Marcy J. Bubar et al.   PLoS One

Dopamine and Octopamine Influence Avoidance Learning of Honey Bees in a Place Preference Assay

(2011) Maitreyi Agarwal et al.   PLoS One

Optical Dissection of Neural Circuits Responsible for Drosophila Larval Locomotion with Halorhodopsin

(2011) Kengo Inada et al.   PLoS One

Distinct molecular underpinnings of Drosophila olfactory trace conditioning

(2011) Y. Shuai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary conservation of the habenular nuclei and their circuitry controlling the dopamine and 5-hydroxytryptophan (5-HT) systems

(2011) M. Stephenson-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila

(2011) P.-T. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems

(2011) Tuan Leng Tay et al.   Nature Communications

The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons

(2011) Mary Kay Lobo et al.   Frontiers in Neuroanatomy

Modulation of the mesolimbic dopamine system by leptin

(2010) Darren M. Opland et al.   BRAIN RESEARCH

Specific Dopaminergic Neurons for the Formation of Labile Aversive Memory

(2010) Yoshinori Aso et al.   CURRENT BIOLOGY

Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution

(2010) Ann-Shyn Chiang et al.   CURRENT BIOLOGY

A Computational Model of How Cholinergic Interneurons Protect Striatal-dependent Learning

(2010) F. Gregory Ashby et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Chemical neuroanatomy of the dorsal raphe nucleus and adjacent structures of the mouse brain

(2010) Wenyu Fu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats

(2010) Maura L. Perry et al.   JOURNAL OF NEUROCHEMISTRY

Distinct Roles of Synaptic Transmission in Direct and Indirect Striatal Pathways to Reward and Aversive Behavior

(2010) Takatoshi Hikida et al.   NEURON

Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas

(2010) D. Quarta et al.   NEUROPHARMACOLOGY

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

Writing Memories with Light-Addressable Reinforcement Circuitry

(2009) Adam Claridge-Chang et al.   CELL

A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila

(2009) Michael J. Krashes et al.   CELL

Dopamine counteracts octopamine signalling in a neural circuit mediating food response in C. elegans

(2009) Satoshi Suo et al.   EMBO JOURNAL

Serotonin and GABA are colocalized in restricted groups of neurons in the larval sea lamprey brain: insights into the early evolution of neurotransmitter colocalization in vertebrates

(2009) Antón Barreiro-Iglesias et al.   JOURNAL OF ANATOMY

Different Pedunculopontine Tegmental Neurons Signal Predicted and Actual Task Rewards

(2009) K.-i. Okada et al.   JOURNAL OF NEUROSCIENCE

Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum

(2009) W. Matsuda et al.   JOURNAL OF NEUROSCIENCE

Dynamics of Learning-Related cAMP Signaling and Stimulus Integration in the Drosophila Olfactory Pathway

(2009) Seth M. Tomchik et al.   NEURON

Contrasting Role of Octopamine in Appetitive and Aversive Learning in the Crab Chasmagnathus

(2009) Laura Kaczer et al.   PLoS One

Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli

(2009) F. Brischoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain organization and the origin of insects: an assessment

(2009) N. J. Strausfeld   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology

(2008) U Maskos   BRITISH JOURNAL OF PHARMACOLOGY

Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP

(2008) Andreas T. Sørensen et al.   EXPERIMENTAL NEUROLOGY

A Dopamine–Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons

(2008) Can Ozan Tan et al.   JOURNAL OF NEUROPHYSIOLOGY

Midbrain Dopaminergic Neurons and Striatal Cholinergic Interneurons Encode the Difference between Reward and Aversive Events at Different Epochs of Probabilistic Classical Conditioning Trials

(2008) M. Joshua et al.   JOURNAL OF NEUROSCIENCE

An internal thermal sensor controlling temperature preference in Drosophila

(2008) Fumika N. Hamada et al.   NATURE

The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning

(2008) Xu Liu et al.   NATURE NEUROSCIENCE

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

(2008) R.G. Nair-Roberts et al.   NEUROSCIENCE