Natural Cell Patches: Melanin Nanoparticles for MR Imaging‐Guided Antiatherosclerosis Therapy via Attenuating Macrophage Pyroptosis

Targeting the Microenvironment of Vulnerable Atherosclerotic Plaques: An Emerging Diagnosis and Therapy Strategy for Atherosclerosis

(2022) Shuai Zhang et al.   ADVANCED MATERIALS

Plaque‐Targeted Rapamycin Spherical Nucleic Acids for Synergistic Atherosclerosis Treatment

(2022) Yuanyuan Guo et al.   Advanced Science

NLRP3 inflammasome as a key driver of vascular disease

(2021) Masafumi Takahashi   CARDIOVASCULAR RESEARCH

NLRP3 inflammasome in cancer and metabolic diseases

(2021) Bhesh Raj Sharma et al.   NATURE IMMUNOLOGY

Channelling inflammation: gasdermins in physiology and disease

(2021) Xing Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Gasdermin D pore structure reveals preferential release of mature interleukin-1

(2021) Shiyu Xia et al.   NATURE

Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

(2021) Xiao He et al.   PHARMACOLOGICAL RESEARCH

A Highly Specific Multiple Enhancement Theranostic Nanoprobe for PET/MRI/PAI Image‐Guided Radioisotope Combined Photothermal Therapy in Prostate Cancer

(2021) Lei Xia et al.   Small

Targeted and activatable nanosystem for fluorescent and optoacoustic imaging of immune-mediated inflammatory diseases and therapy via inhibiting NF-κB/NLRP3 pathways

(2021) Lihe Sun et al.   Bioactive Materials

Dying cells fan the flames of inflammation

(2021) Kim Newton et al.   SCIENCE

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Melanin‐Like Nanomaterials for Advanced Biomedical Applications: A Versatile Platform with Extraordinary Promise

(2020) Heng Liu et al.   Advanced Science

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

(2020) Cheng Gao et al.   Nature Communications

Green tea polyphenols and epigallocatechin-3-gallate protect against perfluorodecanoic acid induced liver damage and inflammation in mice by inhibiting NLRP3 inflammasome activation

(2019) Dongxu Wang et al.   FOOD RESEARCH INTERNATIONAL

Inflammation as a Treatment Target after Acute Myocardial Infarction

(2019) L. Kristin Newby   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction

(2019) Jean-Claude Tardif et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rescue from a fiery death: A therapeutic endeavor

(2019) Nobuhiko Kayagaki et al.   SCIENCE

Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis and Atherogenesis

(2018) Marit Westerterp et al.   CIRCULATION

NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis

(2018) Alena Grebe et al.   CIRCULATION RESEARCH

Interleukin-1 blockade in cardiovascular diseases: a clinical update

(2018) Leo F Buckley et al.   EUROPEAN HEART JOURNAL

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

(2018) Xianxian Wu et al.   Cell Death & Disease

Novel Beneficial Cardiovascular Effects of Natural Activators of Autophagy

(2018) Giacomo Frati et al.   CIRCULATION RESEARCH

Nanoimmunotherapy to treat ischaemic heart disease

(2018) Raphaël Duivenvoorden et al.   Nature Reviews Cardiology

Inflammation, Immunity, and Infection in Atherothrombosis

(2018) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Clinician’s Guide to Reducing Inflammation to Reduce Atherothrombotic Risk

(2018) Paul M Ridker   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke

(2017) Yanlan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration

(2017) Seyed Fazel Nabavi et al.   BIOTECHNOLOGY ADVANCES

Dragon fruit-like biocage as an iron trapping nanoplatform for high efficiency targeted cancer multimodality imaging

(2015) Min Yang et al.   BIOMATERIALS

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Transferring Biomarker into Molecular Probe: Melanin Nanoparticle as a Naturally Active Platform for Multimodality Imaging

(2014) Quli Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NLRP3 Inflammasomes Show High Expression in Aorta of Patients with Atherosclerosis

(2013) Fei Zheng et al.   Heart Lung and Circulation

Autophagy, polyphenols and healthy ageing

(2012) Kathrin Pallauf et al.   AGEING RESEARCH REVIEWS

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

(2011) Pei-Yi Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE