Alpha 7 nicotinic receptor coupling to heterotrimeric G proteins modulates RhoA activation, cytoskeletal motility, and structural growth

Nicotinic modulation of hippocampal cell signaling and associated effects on learning and memory

(2016) Munir Gunes Kutlu et al.   PHYSIOLOGY & BEHAVIOR

Identification of muscarinic receptor subtypes involved in catecholamine secretion in adrenal medullary chromaffin cells by genetic deletion

(2015) Keita Harada et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neurite outgrowth resistance to rho kinase inhibitors in PC12 Adh cell

(2015) Hua Yin et al.   CELL BIOLOGY INTERNATIONAL

MiR-133b Promotes Neurite Outgrowth by Targeting RhoA Expression

(2015) Xiao Cheng Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Activation of Microtubule Dynamics Increases Neuronal Growth via the Nerve Growth Factor (NGF)- and Gαs-mediated Signaling Pathways

(2015) Tulika Sarma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors

(2015) Justin R. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Upregulation of  4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine Reward

(2015) J. Ngolab et al.   JOURNAL OF NEUROSCIENCE

Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses

(2015) Joseph G. Duman et al.   NEUROSCIENCE LETTERS

Nicotinic ACh receptors as therapeutic targets in CNS disorders

(2015) Kelly T. Dineley et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation

(2015) Xingxiu Pan et al.   Molecular Brain

Merging old and new perspectives on nicotinic acetylcholine receptors

(2014) Roger L. Papke   BIOCHEMICAL PHARMACOLOGY

Gαq signalling: The new and the old

(2014) Guzmán Sánchez-Fernández et al.   CELLULAR SIGNALLING

Microtubule dynamics at the growth cone are mediated by α7 nicotinic receptor activation of a Gαq and IP3 receptor pathway

(2014) Jacob C. Nordman et al.   FASEB JOURNAL

Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture

(2014) Zhenying Han et al.   JOURNAL OF NEUROCHEMISTRY

A Novel Mechanism for Nicotinic Potentiation of Glutamatergic Synapses

(2014) A. W. Halff et al.   JOURNAL OF NEUROSCIENCE

Discovery and characterization of small molecules that target the GTPase Ral

(2014) Chao Yan et al.   NATURE

Nicotine promotes cell proliferation and induces resistance to cisplatin by α7 nicotinic acetylcholine receptor-mediated activation in Raw264.7 and El4 cells

(2014) YAN YAN WANG et al.   ONCOLOGY REPORTS

Image Analysis for the Quantitative Comparison of Stress Fibers and Focal Adhesions

(2014) Alberto Elosegui-Artola et al.   PLoS One

Tetraspanin CD9 Regulates Cell Contraction and Actin Arrangement via RhoA in Human Vascular Smooth Muscle Cells

(2014) Michael J. Herr et al.   PLoS One

Effect of varenicline on aspects of inhibitory control in smokers

(2014) A. J. Austin et al.   PSYCHOPHARMACOLOGY

Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration

(2014) Trisha R. Stankiewicz et al.   Frontiers in Cellular Neuroscience

Virtual finger boosts three-dimensional imaging and microsurgery as well as terabyte volume image visualization and analysis

(2014) Hanchuan Peng et al.   Nature Communications

Cellular mechanisms of the 5-HT7receptor-mediated signaling

(2014) Daria Guseva et al.   Frontiers in Behavioral Neuroscience

Axon growth inhibition by RhoA/ROCK in the central nervous system

(2014) Yuki Fujita et al.   Frontiers in Neuroscience

Are nicotinic acetylcholine receptors coupled to G proteins?

(2013) Nadine Kabbani et al.   BIOESSAYS

Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells

(2013) Nagendra S. Singh et al.   CELLULAR SIGNALLING

RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration

(2013) K.-i. Katayama et al.   DEVELOPMENT

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors

(2013) Brandon J. Henderson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Galanin stimulates neurite outgrowth from sensory neurons by inhibition of Cdc42 and Rho GTPases and activation of cofilin

(2013) Sally-Ann Hobson et al.   JOURNAL OF NEUROCHEMISTRY

Axon targeting of the alpha 7 nicotinic receptor in developing hippocampal neurons by Gprin1 regulates growth

(2013) Jacob C. Nordman et al.   JOURNAL OF NEUROCHEMISTRY

A mutation in the extracellular domain of the α7 nAChR reduces calcium permeability

(2013) José O. Colón-Sáez et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Nicotine Elicits Prolonged Calcium Signaling along Ventral Hippocampal Axons

(2013) Chongbo Zhong et al.   PLoS One

Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location

(2013) Joachim Goedhart et al.   Scientific Reports

Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gαq/11 - p63RhoGEF - RhoA Axis

(2013) Peter Siegert et al.   PLoS Pathogens

Antagonistic activities of Rho and Rac GTPases underlie the transition from neural crest delamination to migration

(2012) Irit Shoval et al.   DEVELOPMENTAL DYNAMICS

An interaction between α7 nicotinic receptors and a G-protein pathway complex regulates neurite growth in neural cells

(2012) Jacob C. Nordman et al.   JOURNAL OF CELL SCIENCE

Glutamatergic Synapse Formation is Promoted by  7-Containing Nicotinic Acetylcholine Receptors

(2012) A. F. Lozada et al.   JOURNAL OF NEUROSCIENCE

Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis

(2012) Lei Xing et al.   MOLECULAR BIOLOGY OF THE CELL

Cholesterol Modulates the Rate and Mechanism of Acetylcholine Receptor Internalization

(2011) Virginia Borroni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Phase I/IIa Clinical Trial of a Recombinant Rho Protein Antagonist in Acute Spinal Cord Injury

(2011) Michael G. Fehlings et al.   JOURNAL OF NEUROTRAUMA

Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells

(2011) Albert J. Keung et al.   STEM CELLS

α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Attenuates Early Brain Injury in a Perforation Model of Subarachnoid Hemorrhage in Rats

(2011) Kamil Duris et al.   STROKE

Nicotinic Acetylcholine Receptor Signaling in Tumor Growth and Metastasis

(2011) Sandeep Singh et al.   Journal of Oncology

Kinesin-12, a Mitotic Microtubule-Associated Motor Protein, Impacts Axonal Growth, Navigation, and Branching

(2010) M. Liu et al.   JOURNAL OF NEUROSCIENCE

Endogenous Signaling through  7-Containing Nicotinic Receptors Promotes Maturation and Integration of Adult-Born Neurons in the Hippocampus

(2010) N. R. Campbell et al.   JOURNAL OF NEUROSCIENCE

Localized alteration of microtubule polymerization in response to guidance cues

(2010) Terri-Ann N. Kelly et al.   JOURNAL OF NEUROSCIENCE RESEARCH

V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets

(2010) Hanchuan Peng et al.   NATURE BIOTECHNOLOGY

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

(2010) Jean-Pierre Changeux   NATURE REVIEWS NEUROSCIENCE

Differences in Gα12- and Gα13-mediated plasma membrane recruitment of p115-RhoGEF

(2009) Raja Bhattacharyya et al.   CELLULAR SIGNALLING

Coupling of Ionic Events to Protein Kinase Signaling Cascades upon Activation of α7 Nicotinic Receptor

(2009) Alexander I. Chernyavsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RhoA downstream of Gq and G12/13 pathways regulates protease-activated receptor-mediated dense granule release in platelets

(2008) Jianguo Jin et al.   BIOCHEMICAL PHARMACOLOGY

Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway

(2008) Sudha Kumari et al.   JOURNAL OF CELL BIOLOGY

Multiple Gi Proteins Participate in Nerve Growth Factor-Induced Activation of c-Jun N-terminal Kinases in PC12 Cells

(2008) Prudence H. Tso et al.   NEUROCHEMICAL RESEARCH