Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action

Ion Channel Formation by Tau Protein: Implications for Alzheimer’s Disease and Tauopathies

(2015) Nirav Patel et al.   BIOCHEMISTRY

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death

(2015) D. Kanmert et al.   JOURNAL OF NEUROSCIENCE

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

(2015) Harindranath Kadavath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules

(2015) Peter J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders

(2015) Vladimir N. Uversky   Frontiers in Aging Neuroscience

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

(2014) Dennis Janning et al.   MOLECULAR BIOLOGY OF THE CELL

Tau mutants bind tubulin heterodimers with enhanced affinity

(2014) S. Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells

(2013) G. Breuzard et al.   JOURNAL OF CELL SCIENCE

A decade and a half of protein intrinsic disorder: Biology still waits for physics

(2013) Vladimir N. Uversky   PROTEIN SCIENCE

Familial Alzheimer’s Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization

(2012) Megan Murray Gessel et al.   ACS Chemical Neuroscience

Tau Protein Diffuses along the Microtubule Lattice

(2012) Maike H. Hinrichs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease

(2011) Kristina R. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Adriana Ferreira et al.   MOLECULAR MEDICINE

Human polyomavirus JC small regulatory agnoprotein forms highly stable dimers and oligomers: Implications for their roles in agnoprotein function

(2011) A. Sami Saribas et al.   VIROLOGY

Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy

(2010) K. R. Brunden et al.   JOURNAL OF NEUROSCIENCE

Conformational Stability of Syrian Hamster Prion Protein PrP(90−231)

(2010) Megan Grabenauer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation

(2010) Christian Bleiholder et al.   Nature Chemistry

Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment

(2010) Sarika Garg et al.   NEUROBIOLOGY OF AGING

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Microtubule Binding and Trapping at the Tip of Neurites Regulate Tau Motion in Living Neurons

(2009) Carina Weissmann et al.   TRAFFIC

The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

(2008) Nichole E. LaPointe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-Related A30P and A53T Mutants

(2008) Megan Grabenauer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

(2008) K. J. Rosenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA