Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids

Targeting mitochondria metabolism for cancer therapy

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Identifying Glioblastoma Gene Networks Based on Hypergeometric Test Analysis

(2015) Vasileios Stathias et al.   PLoS One

Targeting Metabolic Remodeling in Glioblastoma Multiforme

(2015)   Oncotarget

Asparagine Depletion Potentiates the Cytotoxic Effect of Chemotherapy against Brain Tumors

(2014) Eduard H. Panosyan et al.   MOLECULAR CANCER RESEARCH

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

(2014) M. I. Gross et al.   MOLECULAR CANCER THERAPEUTICS

Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion

(2014) Ji Zhang et al.   MOLECULAR CELL

Isocitrate dehydrogenase status and molecular subclasses of glioma and glioblastoma

(2014) Sameer Agnihotri et al.   Neurosurgical Focus

The Future of Glioblastoma Therapy: Synergism of Standard of Care and Immunotherapy

(2014) Mira Patel et al.   Cancers

Metabolic Modulation of Epigenetics in Gliomas

(2013) Sriram Venneti et al.   BRAIN PATHOLOGY

Therapeutic targeting of EGFR-activated metabolic pathways in glioblastoma

(2013) Qinglei Gao et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage

(2013) Sergey Mareninov et al.   JOURNAL OF NEURO-ONCOLOGY

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

(2013) Martje Tönjes et al.   NATURE MEDICINE

Identification of Retinol Binding Protein 1 Promoter Hypermethylation in Isocitrate Dehydrogenase 1 and 2 Mutant Gliomas

(2012) Arthur P. Chou et al.   JNCI-Journal of the National Cancer Institute

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

DNA Damage Response and Growth Factor Signaling Pathways in Gliomagenesis and Therapeutic Resistance

(2011) M. Squatrito et al.   CANCER RESEARCH

Metabolism and brain cancer

(2011) Suely Kazue Nagahashi Marie et al.   Clinics

Molecular imaging of gliomas with PET: Opportunities and limitations

(2011) C. la Fougere et al.   NEURO-ONCOLOGY

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

(2011) Z. J. Reitman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1

(2010) M. J. Seltzer et al.   CANCER RESEARCH

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

(2008) Yohan Lee et al.   BMC Medical Genomics