Impact on overall survival of the combination of BRAF inhibitors and stereotactic radiosurgery in patients with melanoma brain metastases

Radiosensitization by BRAF inhibitor therapy--mechanism and frequency of toxicity in melanoma patients

(2015) M. Hecht et al.   ANNALS OF ONCOLOGY

Local control after stereotactic radiosurgery for brain metastases in patients with melanoma with and without BRAF mutation and treatment

(2015) David Ly et al.   JOURNAL OF NEUROSURGERY

Impact of BRAF mutation and BRAF inhibition on melanoma brain metastases

(2015) Tulasi Gummadi et al.   MELANOMA RESEARCH

Treatment patterns and outcomes in BRAF V600E-mutant melanoma patients with brain metastases receiving vemurafenib in the real-world setting

(2015) Geoffrey T. Gibney et al.   Cancer Medicine

Development, Implementation, and Use of a Local and Global Clinical Registry for Neurosurgery

(2015) Douglas Kondziolka et al.   Big Data

On demand Gamma-Knife strategy can be safely combined with BRAF inhibitors for the treatment of melanoma brain metastases

(2014) C. Gaudy-Marqueste et al.   ANNALS OF ONCOLOGY

LINAC-based stereotactic radiosurgery to the brain with concurrent vemurafenib for melanoma metastases

(2014) Kamran A. Ahmed et al.   JOURNAL OF NEURO-ONCOLOGY

Response rate to vemurafenib in patients with B-RAF-positive melanoma brain metastases

(2014) Marcin R. Dzienis et al.   MELANOMA RESEARCH

Vemurafenib in patients with BRAFV600 mutation-positive melanoma with symptomatic brain metastases: Final results of an open-label pilot study

(2013) Reinhard Dummer et al.   EUROPEAN JOURNAL OF CANCER

Genotype-dependent cooperation of ionizing radiation with BRAF inhibition in BRAF V600E-mutated carcinomas

(2013) Tina Dasgupta et al.   INVESTIGATIONAL NEW DRUGS

Combination of BRAF Inhibitors and Brain Radiotherapy in Patients With Metastatic Melanoma Shows Minimal Acute Toxicity

(2013) Natalia Rompoti et al.   JOURNAL OF CLINICAL ONCOLOGY

Vemurafenib and radiation therapy in melanoma brain metastases

(2013) Ashwatha Narayana et al.   JOURNAL OF NEURO-ONCOLOGY

Predictors of Survival, Neurologic Death, Local Failure, and Distant Failure After Gamma Knife Radiosurgery for Melanoma Brain Metastases

(2013) Matthew T. Neal et al.   World Neurosurgery

BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma

(2012) Graham J. Mann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

(2012) Axel Hauschild et al.   LANCET

Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial

(2012) Georgina V Long et al.   LANCET ONCOLOGY

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

(2012) Jeffrey A. Sosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

BRAF Mutations in Advanced Cancers: Clinical Characteristics and Outcomes

(2011) Hazem El-Osta et al.   PLoS One

Determinants of survival in patients with brain metastases from cutaneous melanoma

(2010) M Staudt et al.   BRITISH JOURNAL OF CANCER

Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival

(2010) Jan Zakrzewski et al.   CANCER

Outcome predictors of Gamma Knife surgery for melanoma brain metastases

(2010) Donald N. Liew et al.   JOURNAL OF NEUROSURGERY

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE