The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
Authors
Keywords
Glioblastoma, GBM, AKT, AKT1, AKT2, AKT3
Journal
JOURNAL OF NEURO-ONCOLOGY
Volume 130, Issue 1, Pages 43-52
Publisher
Springer Nature
Online
2016-07-15
DOI
10.1007/s11060-016-2220-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression
- (2015) Kristen M. Turner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo
- (2015) Yicheng Lu et al. OncoTargets and Therapy
- Astrocyte Elevated Gene-1 Interacts with Akt Isoform 2 to Control Glioma Growth, Survival, and Pathogenesis
- (2014) B. Hu et al. CANCER RESEARCH
- Making new contacts: the mTOR network in metabolism and signalling crosstalk
- (2014) Mitsugu Shimobayashi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor
- (2014) Melissa Dumble et al. PLoS One
- AKT Pathway Genes Define 5 Prognostic Subgroups in Glioblastoma
- (2014) Anna Joy et al. PLoS One
- Megalencephaly Syndromes and Activating Mutations in the PI3K-AKT Pathway: MPPH and MCAP
- (2013) GHAYDA M. MIRZAA et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models
- (2013) J. Lin et al. CLINICAL CANCER RESEARCH
- Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases
- (2013) Matt Addie et al. JOURNAL OF MEDICINAL CHEMISTRY
- AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development
- (2013) Jianing Zhang et al. Neural Development
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes
- (2012) Jean-Baptiste Rivière et al. NATURE GENETICS
- De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly
- (2012) Jeong Ho Lee et al. NATURE GENETICS
- Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
- (2012) Annapurna Poduri et al. NEURON
- FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method
- (2011) Chaokun Li et al. BMC BIOTECHNOLOGY
- Nonredundant Functions for Akt Isoforms in Astrocyte Growth and Gliomagenesis in an Orthotopic Transplantation Model
- (2011) R. Endersby et al. CANCER RESEARCH
- A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets
- (2011) D. S. Castro et al. GENES & DEVELOPMENT
- High-resolution array CGH defines critical regions and candidate genes for microcephaly, abnormalities of the corpus callosum, and seizure phenotypes in patients with microdeletions of 1q43q44
- (2011) Blake C. Ballif et al. HUMAN GENETICS
- Akt2 and Akt3 play a pivotal role in malignant gliomas
- (2011) H. Mure et al. NEURO-ONCOLOGY
- High -catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression
- (2011) J. Zhang et al. NEURO-ONCOLOGY
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- AT7867 Is a Potent and Oral Inhibitor of AKT and p70 S6 Kinase That Induces Pharmacodynamic Changes and Inhibits Human Tumor Xenograft Growth
- (2010) K. M. Grimshaw et al. MOLECULAR CANCER THERAPEUTICS
- Targeted therapy for malignant glioma patients: Lessons learned and the road ahead
- (2009) Tiffany T. Huang et al. Neurotherapeutics
- Glioblastoma Subclasses Can Be Defined by Activity among Signal Transduction Pathways and Associated Genomic Alterations
- (2009) Cameron Brennan et al. PLoS One
- Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
- (2008) N. Rhodes et al. CANCER RESEARCH
- Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
- (2008) Michael Degtyarev et al. JOURNAL OF CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search