Atypical hemolytic uremic syndrome in the setting of complement-amplifying conditions: case reports and a review of the evidence for treatment with eculizumab

Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial

(2016) Fadi Fakhouri et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Atypical Hemolytic–Uremic Syndrome

(2016) Ali Nayer et al.   AMERICAN JOURNAL OF THERAPEUTICS

Direct evidence of complement activation in HELLP syndrome: A link to atypical hemolytic uremic syndrome

(2016) Arthur J. Vaught et al.   EXPERIMENTAL HEMATOLOGY

Pregnancy outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: a Japanese experience and updated review

(2016) Naoyuki Miyasaka et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The endothelium as the common denominator in malignant hypertension and thrombotic microangiopathy

(2016) Roy O. Mathew et al.   Journal of the American Society of Hypertension

Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome

(2016) Larry A. Greenbaum et al.   KIDNEY INTERNATIONAL

From Gestational Hypertension and Preeclampsia to Atypical Hemolytic Uremic Syndrome

(2016) Han-Mou Tsai et al.   OBSTETRICS AND GYNECOLOGY

Drug-induced thrombotic microangiopathy: Experience of the Oklahoma registry and the BloodCenter of Wisconsin

(2015) Jessica A. Reese et al.   AMERICAN JOURNAL OF HEMATOLOGY

Thrombotic Microangiopathy, Cancer, and Cancer Drugs

(2015) Hassan Izzedine et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Thrombotic Microangiopathy in Systemic Lupus Erythematosus: Efficacy of Eculizumab

(2015) Amr El-Husseini et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Eculizumab for drug-induced de novo posttransplantation thrombotic microangiopathy: A case report

(2015) Kassem Safa et al.   CLINICAL NEPHROLOGY

Neonatal atypical hemolytic uremic syndrome from a factor H mutation treated with eculizumab

(2015) Sheena Sharma et al.   CLINICAL NEPHROLOGY

A case report of undiagnosed postpartum hemolytic uremic syndrome

(2015) Jiao Mu et al.   Diagnostic Pathology

Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn

(2015) Randi Fykse Hallstensen et al.   IMMUNOBIOLOGY

Does Anticomplement Therapy Have a Role in the Management of Malignant Hypertension?

(2015) Han-Mou Tsai   Journal of Clinical Hypertension

Eculizumab in pregnancy-associated atypical hemolytic uremic syndrome: insights for optimizing management

(2015) Erika De Sousa Amorim et al.   JOURNAL OF NEPHROLOGY

Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies

(2015) Christoph Licht et al.   KIDNEY INTERNATIONAL

Actualización en síndrome hemolítico urémico atípico: diagnóstico y tratamiento. Documento de consenso

(2015) Josep M. Campistol et al.   NEFROLOGIA

Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

(2015) Richard J. Kelly et al.   NEW ENGLAND JOURNAL OF MEDICINE

An international consensus approach to the management of atypical hemolytic uremic syndrome in children

(2015) Chantal Loirat et al.   PEDIATRIC NEPHROLOGY

The Complement System in Lupus Nephritis

(2015) Daniel J. Birmingham et al.   SEMINARS IN NEPHROLOGY

The complement system in systemic lupus erythematosus: an update

(2014) Jonatan Leffler et al.   ANNALS OF THE RHEUMATIC DISEASES

Drug-induced thrombotic microangiopathy: a systematic review of published reports

(2014) Z. L. Al-Nouri et al.   BLOOD

Syndromes of Thrombotic Microangiopathy

(2014) James N. George et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dramatic effects of eculizumab in a child with diffuse proliferative lupus nephritis resistant to conventional therapy

(2014) Rosanna Coppo et al.   PEDIATRIC NEPHROLOGY

Eculizumab in the treatment of atypical hemolytic uremic syndrome in an infant leads to cessation of peritoneal dialysis and improvement of severe hypertension

(2014) Toshiyuki Ohta et al.   PEDIATRIC NEPHROLOGY

Atypical HUS due to factor H antibodies in an adult patient successfully treated with eculizumab

(2014) Hefziba Green et al.   RENAL FAILURE

Spectrum of Complement-Mediated Thrombotic Microangiopathies: Pathogenetic Insights Identifying Novel Treatment Approaches

(2014) Magdalena Riedl et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Innovative therapeutic approach: Sequential treatment with plasma exchange and eculizumab in a pregnant woman affected by atypical hemolytic-uremic syndrome

(2014) Maria Pia Mussoni et al.   TRANSFUSION AND APHERESIS SCIENCE

Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome

(2013) M. Le Quintrec et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Successful Treatment of the Postpartum Atypical Hemolytic Uremic Syndrome With Eculizumab

(2013) Stefan Zschiedrich et al.   ANNALS OF INTERNAL MEDICINE

Use of eculizumab in refractory gemcitabine-induced thrombotic microangiopathy

(2013) Michael Starck et al.   BRITISH JOURNAL OF HAEMATOLOGY

Genetics and Outcome of Atypical Hemolytic Uremic Syndrome: A Nationwide French Series Comparing Children and Adults

(2013) V. Fremeaux-Bacchi et al.   Clinical Journal of the American Society of Nephrology

Managing and preventing atypical hemolytic uremic syndrome recurrence after kidney transplantation

(2013) Marina Noris et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

(2013) C.M. Legendre et al.   NEW ENGLAND JOURNAL OF MEDICINE

Eculizumab for Atypical Hemolytic Uremic Syndrome in Pregnancy

(2013) Gianluigi Ardissino et al.   OBSTETRICS AND GYNECOLOGY

Atypical Hemolytic Uremic Syndrome

(2013) David Kavanagh et al.   SEMINARS IN NEPHROLOGY

The spectrum of renal thrombotic microangiopathy in lupus nephritis

(2013) Di Song et al.   ARTHRITIS RESEARCH & THERAPY

Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation

(2012) J. Zuber et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Relapse of aHUS after discontinuation of therapy with eculizumab in a patient with aHUS and factor H mutation

(2012) Ryan Carr et al.   ANNALS OF HEMATOLOGY

The complement system in pediatric systemic lupus erythematosus, atypical hemolytic uremic syndrome, and complocentric membranoglomerulopathies

(2012) Bradley W. Ornstein et al.   CURRENT OPINION IN RHEUMATOLOGY

Plasmapheresis in systemic lupus erythematosus with thrombotic microangiopathy

(2012) R. Ramachandran et al.   INTERNAL MEDICINE JOURNAL

Haemolytic-uraemic syndrome during severe lupus nephritis: efficacy of plasma exchange

(2012) M. Samson et al.   INTERNAL MEDICINE JOURNAL

STEC-HUS, atypical HUS and TTP are all diseases of complement activation

(2012) Marina Noris et al.   Nature Reviews Nephrology

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

(2012) Julien Zuber et al.   Nature Reviews Nephrology

Thrombotic microangiopathy and associated renal disorders

(2012) T. Barbour et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Neonatal onset atypical hemolytic uremic syndrome successfully treated with eculizumab

(2012) Nesrin Besbas et al.   PEDIATRIC NEPHROLOGY

Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics

(2012) Lianne M. Geerdink et al.   PEDIATRIC NEPHROLOGY

Eculizumab in Acute Recurrence of Thrombotic Microangiopathy After Renal Transplantation

(2011) K. Hadaya et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Clinical Features of Malignant Hypertension with Thrombotic Microangiopathy

(2011) Tetsu Akimoto et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Thrombotic Microangiopathy with Targeted Cancer Agents

(2011) John A. Blake-Haskins et al.   CLINICAL CANCER RESEARCH

Atypical Hemolytic–Uremic Syndrome in a Child Presenting With Malignant Hypertension

(2011) Alisha Totina et al.   CLINICAL PEDIATRICS

Endothelial dysfunction, platelet activation, thrombogenesis and fibrinolysis in patients with hypertensive crisis

(2011) Bert-Jan H van den Born et al.   JOURNAL OF HYPERTENSION

Early diagnosis and management of postpartum hemolytic uremic syndrome with plasma exchange

(2011) Manisha Shrivastava et al.   TRANSFUSION AND APHERESIS SCIENCE

Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

(2011) Andreas Jönsen et al.   ARTHRITIS RESEARCH & THERAPY

Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

(2011) Jian Zhao et al.   PLoS Genetics

The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease

(2010) T. Sugihara et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Rapidly progressive lupus nephritis and concomitant thrombotic microangiopathy

(2010) Chems Gharbi et al.   Clinical and Experimental Nephrology

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

(2010) M. Noris et al.   Clinical Journal of the American Society of Nephrology

Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations

(2010) F. Fakhouri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Eculizumab induces long-term remission in recurrent post-transplant HUS associated with C3 gene mutation

(2010) Samhar I. Al-Akash et al.   PEDIATRIC NEPHROLOGY

Thrombotic microangiopathy in systemic lupus erythematosus: a cohort study in North Taiwan

(2010) M.-H. Chen et al.   RHEUMATOLOGY

Plasmatherapy in Atypical Hemolytic Uremic Syndrome

(2010) Chantal Loirat et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Eculizumab for Atypical Hemolytic–Uremic Syndrome

(2009) Jens Nürnberger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atypical Hemolytic–Uremic Syndrome

(2009) Marina Noris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hemolytic uremic syndrome with ischemic glomerulonephropathy and obliterative vasculopathy in a systemic sclerosis patient treated with cyclosporine-A

(2009) Wei-Sheng Chen et al.   RHEUMATOLOGY INTERNATIONAL

Renal Thrombotic Microangiopathies Induced by Severe Hypertension

(2008) Bo ZHANG et al.   HYPERTENSION RESEARCH

Aldosterone and the vascular system

(2008) Victoria Cachofeiro et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome

(2008) Gema Ariceta et al.   PEDIATRIC NEPHROLOGY