The dopamine D2 receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamics

Structure-Based Virtual Screening for Dopamine D2Receptor Ligands as Potential Antipsychotics

(2016) Agnieszka A. Kaczor et al.   ChemMedChem

In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic

(2016) Agnieszka A. Kaczor et al.   NEUROCHEMISTRY INTERNATIONAL

Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques

(2015) Serdar Durdagi et al.   ACS Chemical Neuroscience

Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes

(2015) Hugo R. Arias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Analysis of Human Dopamine D3Receptor Quaternary Structure

(2015) Sara Marsango et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors

(2015) Agnieszka A. Kaczor et al.   Molecular Informatics

Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor

(2014) Krzysztof Jozwiak et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Dopamine D2 and Adenosine A2A Receptors: Past, Present and Future Trends for the Treatment of Parkinson’s Disease

(2014) M. Jorg et al.   CURRENT MEDICINAL CHEMISTRY

Application of BRET for Studying G Protein-Coupled Receptors

(2014) Agnieszka Kaczor et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Investigation of novel ropinirole analogues: synthesis, pharmacological evaluation and computational analysis of dopamine D2 receptor functionalized congeners and homobivalent ligands

(2014) Manuela Jörg et al.   MedChemComm

Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors

(2013) Agnieszka A. Kaczor et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Single-molecule imaging revealed dynamic GPCR dimerization

(2013) Rinshi S Kasai et al.   CURRENT OPINION IN CELL BIOLOGY

Modeling Complexes of Transmembrane Proteins: Systematic Analysis of ProteinProtein Docking Tools

(2013) Agnieszka A. Kaczor et al.   Molecular Informatics

Oligomerization of G Protein-Coupled Receptors: Computational Methods

(2012) J. Selent et al.   CURRENT MEDICINAL CHEMISTRY

Oligomerization of G Protein-Coupled Receptors: Biochemical and Biophysical Methods

(2012) A.A. Kaczor et al.   CURRENT MEDICINAL CHEMISTRY

Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies

(2012) B. Trzaskowski et al.   CURRENT MEDICINAL CHEMISTRY

Homobivalent Ligands of the Atypical Antipsychotic Clozapine: Design, Synthesis, and Pharmacological Evaluation

(2012) Fiona M. McRobb et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fractal dimension as a measure of surface roughness of G protein-coupled receptors: implications for structure and function

(2012) Agnieszka A. Kaczor et al.   JOURNAL OF MOLECULAR MODELING

Rational design of the survivin/CDK4 complex by combining protein–protein docking and molecular dynamics simulations

(2012) Jana Selent et al.   JOURNAL OF MOLECULAR MODELING

Bivalent molecular probes for dopamine D2-like receptors

(2011) Daniela Huber et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bivalent Dopamine D2Receptor Ligands: Synthesis and Binding Properties

(2011) Julia Kühhorn et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Lessons from Free Energy Simulations of δ-Opioid Receptor Homodimers Involving the Fourth Transmembrane Helix

(2010) Davide Provasi et al.   BIOCHEMISTRY

Practically Useful: What the RosettaProtein Modeling Suite Can Do for You

(2010) Kristian W. Kaufmann et al.   BIOCHEMISTRY

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

Bioinformatics and molecular modelling approaches to GPCR oligomerization

(2009) Lisa M Simpson et al.   CURRENT OPINION IN PHARMACOLOGY

Progress in Elucidating the Structural and Dynamic Character of G Protein-Coupled Receptor Oligomers for Use in Drug Discovery

(2009) A. Bortolato et al.   CURRENT PHARMACEUTICAL DESIGN

Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization

(2009) Sylwia Łukasiewicz et al.   FEBS Journal

Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?

(2009) Marta Filizola   LIFE SCIENCES