Pivotal role of high-mobility group box 1 (HMGB1) signaling pathways in glioma development and progression

Macrophage migration inhibitory factor promotes breast cancer metastasis via activation of HMGB1/TLR4/NF kappa B axis

(2016) Wei Lv et al.   CANCER LETTERS

High-mobility group Box 1: A novel inducer of the epithelial–mesenchymal transition in colorectal carcinoma

(2015) Lingyin Zhu et al.   CANCER LETTERS

High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity

(2015) M. Chen et al.   CANCER RESEARCH

MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation

(2015) Yu Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Unknown

(2015) Huan Yang et al.   MOLECULAR MEDICINE

Glioblastoma multiforme: Pathogenesis and treatment

(2015) Constantinos Alifieris et al.   PHARMACOLOGY & THERAPEUTICS

mir-129-5p Attenuates Irradiation-Induced Autophagy and Decreases Radioresistance of Breast Cancer Cells by Targeting HMGB1

(2015) Jing Luo et al.   MEDICAL SCIENCE MONITOR

Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation

(2015) Jennifer R. Molina et al.   NEOPLASIA

High-grade glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2014) R. Stupp et al.   ANNALS OF ONCOLOGY

Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9

(2014) Young Dae Lee et al.   BMB Reports

The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines

(2014) Ruo-Chan Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

HMGB1 in health and disease

(2014) Rui Kang et al.   MOLECULAR ASPECTS OF MEDICINE

Unknown

(2014) Daolin Tang et al.   MOLECULAR MEDICINE

The epidemiology of glioma in adults: a "state of the science" review

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

HMGB1 promotes cellular proliferation and invasion, suppresses cellular apoptosis in osteosarcoma

(2014) Qingbing Meng et al.   TUMOR BIOLOGY

Recent advances in the role of toll-like receptors and TLR agonists in immunotherapy for human glioma

(2014) Shuanglin Deng et al.   Protein & Cell

Effects of Single or Combined Treatments with Radiation and Chemotherapy on Survival and Danger Signals Expression in Glioblastoma Cell Lines

(2014) Francesca Pasi et al.   Biomed Research International

HMGB1 in Cancer: Good, Bad, or Both?

(2013) R. Kang et al.   CLINICAL CANCER RESEARCH

Growth inhibitory effects of three miR-129 family members on gastric cancer

(2013) Xiuchong Yu et al.   GENE

Inhibition of matrix metalloproteinase-9 and nuclear factor kappa B contribute to melatonin prevention of motility and invasiveness in HepG2 liver cancer cells

(2013) Raquel Ordoñez et al.   JOURNAL OF PINEAL RESEARCH

RAGE and TLRs: Relatives, friends or neighbours?

(2013) Zaridatul Aini Ibrahim et al.   MOLECULAR IMMUNOLOGY

Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion

(2013) K. Vinnakota et al.   NEURO-ONCOLOGY

An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies

(2013) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

(2013) H. Yanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer

(2013) M Karaayvaz et al.   Cell Death & Disease

β-defensin-3 negatively regulates TLR4–HMGB1 axis mediated HLA-G expression in IL-1β treated glioma cells

(2012) Piyushi Gupta et al.   CELLULAR SIGNALLING

S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis

(2012) T. Arumugam et al.   CLINICAL CANCER RESEARCH

HMGB1 is overexpressed in tumor cells and promotes activity of regulatory T cells in patients with head and neck cancer

(2012) Clarissa A. Wild et al.   ORAL ONCOLOGY

Molecular mechanisms of necrosis in glioblastoma: The role of glutamate excitotoxicity

(2010) Evan Noch et al.   CANCER BIOLOGY & THERAPY

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

(2009) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity

(2009) M. Candolfi et al.   CLINICAL CANCER RESEARCH

Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer

(2009) Hye Chung et al.   Journal of Translational Medicine

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE

Treatment options for malignant gliomas, emphasizing towards new molecularly targeted therapies

(2008) Andreas A. Argyriou et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42

(2008) Barry I. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY