Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis

Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

(2015) Qin Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

(2014) Yun Sok Lee et al.   CELL

Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4

(2013) Luciano F. Drager et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Thermoneutrality modifies the impact of hypoxia on lipid metabolism

(2012) Jonathan C. Jun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dietary obesity-associated Hif1  activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system

(2012) J. Krishnan et al.   GENES & DEVELOPMENT

HIF-1α regulation in mammalian hibernators: role of non-coding RNA in HIF-1α control during torpor in ground squirrels and bats

(2012) Yulia Maistrovski et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Selective Inhibition of Hypoxia-Inducible Factor 1  Ameliorates Adipose Tissue Dysfunction

(2012) K. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolic Consequences of High-Fat Diet Are Attenuated by Suppression of HIF-1α

(2012) Mi-Kyung Shin et al.   PLoS One

Regulation of HIF-1α activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia

(2011) Qing He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα

(2011) Milica Vucetic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet-Fed Mice

(2011) C. Jiang et al.   DIABETES

Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning

(2010) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients

(2010) Lingyun Zhu et al.   CELL RESEARCH

Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice

(2010) Xinmei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic adaptation of mice in a cool environment

(2010) Kunitoshi Uchida et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia-Inducible Factor 1  Induces Fibrosis and Insulin Resistance in White Adipose Tissue

(2009) N. Halberg et al.   MOLECULAR AND CELLULAR BIOLOGY

PGC-1  is coupled to HIF-1 -dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells

(2009) K. A. O'Hagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE