60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides

60 YEARS OF POMC: From the prohormone theory to pro-opiomelanocortin and to proprotein convertases (PCSK1 to PCSK9)

(2016) Michel Chrétien et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH

(2016) Erica J P Anderson et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells

(2016) Niamh X. Cawley et al.   MOLECULAR ENDOCRINOLOGY

60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin C

(2015) Dhivya Kumar et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Truncating Homozygous Mutation of Carboxypeptidase E (CPE) in a Morbidly Obese Female with Type 2 Diabetes Mellitus, Intellectual Disability and Hypogonadotrophic Hypogonadism

(2015) Suzanne I. M. Alsters et al.   PLoS One

Kinesin-2: A Family of Heterotrimeric and Homodimeric Motors with Diverse Intracellular Transport Functions

(2013) Jonathan M. Scholey   Annual Review of Cell and Developmental Biology

Melatonin receptor activation suppresses adrenocorticotropin production via BMP-4 action by pituitary AtT20 cells

(2013) Naoko Tsukamoto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hypothalamic and Pituitary Clusterin Modulates Neurohormonal Responses to Stress

(2013) Mi-Seon Shin et al.   NEUROENDOCRINOLOGY

The Regulated Secretory Pathway and Human Disease: Insights from Gene Variants and Single Nucleotide Polymorphisms

(2013) Wei-Jye Lin et al.   Frontiers in Endocrinology

Role of Adaptor Proteins in Secretory Granule Biogenesis and Maturation

(2013) Mathilde L. Bonnemaison et al.   Frontiers in Endocrinology

New Roles of Carboxypeptidase E in Endocrine and Neural Function and Cancer

(2012) Niamh X. Cawley et al.   ENDOCRINE REVIEWS

γ-Adducin Promotes Process Outgrowth and Secretory Protein Exit from the Golgi Apparatus

(2012) Hong Lou et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Multiple Sorting Systems for Secretory Granules Ensure the Regulated Secretion of Peptide Hormones

(2012) Meng Sun et al.   TRAFFIC

Hypothalamic proopiomelanocortin processing and the regulation of energy balance

(2011) Sharon L. Wardlaw   EUROPEAN JOURNAL OF PHARMACOLOGY

Yapsin 1 immunoreactivity in α-cells of human pancreatic islets: implications for the processing of human proglucagon by mammalian aspartic proteases

(2011) Niamh X Cawley et al.   JOURNAL OF ENDOCRINOLOGY

Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density

(2010) Niamh X. Cawley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effects of Bone Morphogenetic Protein (BMP) on Adrenocorticotropin Production by Pituitary Corticotrope Cells: Involvement of Up-Regulation of BMP Receptor Signaling by Somatostatin Analogs

(2010) Naoko Tsukamoto et al.   ENDOCRINOLOGY

Carboxypeptidase E cytoplasmic tail mediates localization of synaptic vesicles to the pre-active zone in hypothalamic pre-synaptic terminals

(2010) Hong Lou et al.   JOURNAL OF NEUROCHEMISTRY

Acute inhibition of carboxypeptidase E expression in AtT-20 cells does not affect regulated secretion of ACTH

(2010) Robert J. Kemppainen et al.   REGULATORY PEPTIDES

Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis

(2009) Xin Zhang et al.   JOURNAL OF NEUROCHEMISTRY

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

(2009) Leona Plum et al.   NATURE MEDICINE

Treatment of Adrenocorticotropin-Dependent Cushing’s Syndrome: A Consensus Statement

(2008) B. M. K. Biller et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The stimulation of mitogenic signaling pathways by N-POMC peptides

(2008) David J. Pepper et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Carboxypeptidase E Cytoplasmic Tail-Driven Vesicle Transport Is Key for Activity-Dependent Secretion of Peptide Hormones

(2008) Joshua J. Park et al.   MOLECULAR ENDOCRINOLOGY

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS