Mitofusin 2 attenuates the histone acetylation at collagen IV promoter in diabetic nephropathy

TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions

(2016) Inmaculada Martínez-Reyes et al.   MOLECULAR CELL

Acute restraint stress increases carotid reactivity in type-I diabetic rats by enhancing Nox4/NADPH oxidase functionality

(2015) Josimar D. Moreira et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways

(2015) Cheng Peng et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice

(2015) Yong-Ming Yan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aberrant CpG methylation of theTFAP2Agene constitutes a mechanism for loss ofTFAP2Aexpression in human metastatic melanoma

(2015) Andrea R Hallberg et al.   Epigenetics

Inactivation of AMPK Mediates High Phosphate-Induced Extracellular Matrix Accumulation via NOX4/TGFß-1 Signaling in Human Mesangial Cells

(2014) Alexandros Papadimitriou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tumour necrosis factor-α promotes liver ischaemia-reperfusion injury through the PGC-1α/Mfn2 pathway

(2014) Jun Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

(2014) M. Zhan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Enhancer biology and enhanceropathies

(2014) Edwin Smith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Overexpression of mitofusin 2 inhibits reactive astrogliosis proliferation in vitro

(2014) Tao Liu et al.   NEUROSCIENCE LETTERS

Icariin attenuates high glucose-induced type IV collagen and fibronectin accumulation in glomerular mesangial cells by inhibiting transforming growth factor-β production and signalling through G protein-coupled oestrogen receptor 1

(2013) Yi-Chen Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Genetic Deficiency of Anti-Aging GeneKlothoExacerbates Early Nephropathy in STZ-Induced Diabetes in Male Mice

(2013) Yi Lin et al.   ENDOCRINOLOGY

AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function

(2013) Laura L. Dugan et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective role for netrin-1 during diabetic nephropathy

(2013) Eunyoung Tak et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways

(2013) Fabian Anton et al.   MOLECULAR CELL

Tempol ameliorates cardiac fibrosis in streptozotocin-induced diabetic rats: role of oxidative stress in diabetic cardiomyopathy

(2013) Ashraf Taye et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion

(2012) Stefan Vielhaber et al.   ACTA NEUROPATHOLOGICA

Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

(2012) R. Fan et al.   BLOOD

Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?

(2012) Ralph J. DeBerardinis et al.   CELL

Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest

(2012) Alvaro Rada-Iglesias et al.   Cell Stem Cell

Effects of High Glucose on AVP-Induced Hyperplasia, Hypertrophy, and Type IV Collagen Synthesis in Cultured Rat Mesangial Cells

(2012) Atsuo Tahara et al.   ENDOCRINE RESEARCH

Transcription factors: from enhancer binding to developmental control

(2012) François Spitz et al.   NATURE REVIEWS GENETICS

A two-way street: reciprocal regulation of metabolism and signalling

(2012) Kathryn E. Wellen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

Renoprotective antioxidant effect of alagebrium in experimental diabetes

(2011) Jehyun Park et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes

(2010) Mahua Choudhury et al.   ALCOHOL

Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1α or PGC-1β and mitofusin 2 in skeletal muscle in type 2 diabetes

(2010) Antonio Zorzano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex

(2010) A. Misko et al.   JOURNAL OF NEUROSCIENCE

Diabetic kidney disease: act now or pay later

(2010) Robert C. Atkins et al.   KIDNEY INTERNATIONAL

Pigment epithelium-derived factor inhibits advanced glycation end product-elicited mesangial cell damage by blocking NF-κB activation

(2010) Yuichiro Ide et al.   MICROVASCULAR RESEARCH

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Fusing for stability

(2010) Kim Baumann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10

(2010) Sufyan G. Sayyed et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Acetylation of H4K12 in porcine oocytes during in vitro aging: potential role of ooplasmic reactive oxygen species

(2010) Mao-Sheng Cui et al.   THERIOGENOLOGY

Insulin induced alteration in post-translational modifications of histone H3 under a hyperglycemic condition in L6 skeletal muscle myoblasts

(2009) Dhiraj G. Kabra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Subjects With Early-Onset Type 2 Diabetes Show Defective Activation of the Skeletal Muscle PGC-1 /Mitofusin-2 Regulatory Pathway in Response to Physical Activity

(2009) M. I. Hernandez-Alvarez et al.   DIABETES CARE

Rosiglitazone Prevents High Glucose-Induced Vascular Endothelial Growth Factor and Collagen IV Expression in Cultured Mesangial Cells

(2009) Catharine Whiteside et al.   Experimental Diabetes Research

Synthetic retinoid Am80 inhibits interaction of KLF5 with RARα through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells

(2009) Xin-hua Zhang et al.   FEBS LETTERS

Mouse Models of Diabetic Nephropathy

(2009) F. C. Brosius et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Modification of Collagen IV by Glucose or Methylglyoxal Alters Distinct Mesangial Cell Functions

(2009) A. Pozzi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras

(2009) Olga Martins de Brito et al.   MITOCHONDRION

Oxidative Stress CausesIL8Promoter Hyperacetylation in Cystic Fibrosis Airway Cell Models

(2008) Toni R. Bartling et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mitochondrial fusion and function in Charcot–Marie–Tooth type 2A patient fibroblasts with mitofusin 2 mutations

(2008) Elizabeth A. Amiott et al.   EXPERIMENTAL NEUROLOGY

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

(2008) Assam El-Osta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Green tea (Camellia sinensis) Attenuates Nephropathy by Downregulating Nox4 NADPH Oxidase in Diabetic Spontaneously Hypertensive Rats

(2008) Pérola D. B. Ribaldo et al.   JOURNAL OF NUTRITION