Defining the origin, evolution, and immune composition of SDH-deficient renal cell carcinoma

Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron

(2021) Lihe Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

(2021) Gerda Kildisiute et al.   Science Advances

Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma

(2021) Toni K. Choueiri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single cell derived mRNA signals across human kidney tumors

(2021) Matthew D. Young et al.   Nature Communications

TGF-beta: a master immune regulator

(2020) Christopher Larson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

(2019) Mazène Hochane et al.   PLOS BIOLOGY

Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Immune Checkpoint Inhibition Is the New Backbone in First-line Treatment of Metastatic Clear-cell Renal Cell Carcinoma

(2019) Laurence Albiges et al.   EUROPEAN UROLOGY

The Impact Of Succinate Dehydrogenase Gene (SDH) Mutations In Renal Cell Carcinoma (RCC): A Systematic Review

(2019) Seyed Mohammad Kazem Aghamir et al.   OncoTargets and Therapy

Embryonal precursors of Wilms tumor

(2019) Tim H. H. Coorens et al.   SCIENCE

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

(2018) Thomas J. Mitchell et al.   CELL

Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genesSDHB,SDHCandSDHD

(2018) Katrina A Andrews et al.   JOURNAL OF MEDICAL GENETICS

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

(2018) Christopher J. Ricketts et al.   Cell Reports

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma

(2018) Maria I. Carlo et al.   JAMA Oncology

Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta 

(2018) Yawei Liu et al.   CELL RESEARCH

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

(2018) Sanjeev Mariathasan et al.   NATURE

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

(2018) Matthew D. Young et al.   SCIENCE

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion

(2018) Sabine Heitzeneder et al.   JNCI-Journal of the National Cancer Institute

A Systematic Review and Meta-analysis Comparing the Effectiveness and Adverse Effects of Different Systemic Treatments for Non-clear Cell Renal Cell Carcinoma

(2017) Sergio Fernández-Pello et al.   EUROPEAN UROLOGY

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo

(2017) Andreas Kirschner et al.   OncoImmunology

Fumarate Hydratase–deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome

(2016) Kiril Trpkov et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

A Landscape of Pharmacogenomic Interactions in Cancer

(2016) Francesco Iorio et al.   CELL

Insulin-like Growth Factors and Kidney Disease

(2015) Leon A. Bach et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Succinate dehydrogenase B: a new prognostic biomarker in clear cell renal cell carcinoma

(2015) Kristine M. Cornejo et al.   HUMAN PATHOLOGY

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

Succinate Dehydrogenase (SDH)-deficient Renal Carcinoma

(2014) Anthony J. Gill et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Renal Cell Carcinoma in Tuberous Sclerosis Complex

(2014) Ping Yang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma

(2014) Sean R Williamson et al.   MODERN PATHOLOGY

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

(2014) Niccolo Bolli et al.   Nature Communications

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Renal Tumors Associated With Germline SDHB Mutation Show Distinctive Morphology

(2011) Anthony J. Gill et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SDH mutations in cancer

(2011) Chiara Bardella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Renal Tumors and Hereditary Pheochromocytoma-Paraganglioma Syndrome Type 4

(2011) Anthony J. Gill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renal carcinoma with giant mitochondria associated with germ-line mutation and somatic loss of the succinate dehydrogenase B gene

(2010) Sarah L Housley et al.   HISTOPATHOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

(2008) Peter J Campbell et al.   NATURE GENETICS