Macrophage‐derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment

MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice

(2021) Wei Ying et al.   Cell Metabolism

Role of Macrophages in the Endocrine System

(2021) Abdul Rehman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice

(2021) Carolina Lliberos et al.   Frontiers in Cell and Developmental Biology

Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal age

(2021) Emmanouella E. Chatzidaki et al.   CURRENT BIOLOGY

Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis

(2021) Amit Kishore et al.   Frontiers in Immunology

Exosomes Derived from M2 Macrophages Exert a Therapeutic Effect via Inhibition of the PI3K/AKT/mTOR Pathway in Rats with Knee Osteoarthritic

(2021) Zha Xi Da-wa et al.   Biomed Research International

Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation

(2020) Yuqing Wu et al.   MOLECULAR CELL

Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo

(2020) Laura Bouchareychas et al.   Cell Reports

Macrophages: an indispensable piece of ovarian health

(2020) Zijing Zhang et al.   BIOLOGY OF REPRODUCTION

The different doses of radiation therapy-induced damage to the ovarian environment in rats

(2020) Gozde Ozge Onder et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing Data

(2020) Lingwei Ma et al.   Frontiers in Genetics

Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study

(2019) Maria C Magnus et al.   BMJ-British Medical Journal

Hydrogel-based delivery of Il-10 improves treatment of bleomycin-induced lung fibrosis in mice

(2019) Elya A. Shamskhou et al.   BIOMATERIALS

KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis

(2019) Yi Wen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miR‐107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K‐AKT signaling pathway by down‐regulating FAT4

(2019) Li Wang et al.   Cancer Medicine

Repeated superovulation increases the risk of osteoporosis and cardiovascular diseases by accelerating ovarian aging in mice

(2018) Jinjin Zhang et al.   Aging-US

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy

(2018) Seema Patel   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Risk of Adverse Pregnancy Outcomes at Advanced Maternal Age

(2018) Line Elmerdahl Frederiksen et al.   OBSTETRICS AND GYNECOLOGY

Insulin-like growth factor-1 (IGF-1) promotes primordial follicle growth and reduces DNA fragmentation through the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signalling pathway

(2018) Maria �. S. Bezerra et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells

(2018) Te-Fu Tsai et al.   OncoTargets and Therapy

Deregulated expression of miR-107 inhibits metastasis of PDAC through inhibition PI3K/Akt signaling via caveolin-1 and PTEN

(2017) Junjie Xiong et al.   EXPERIMENTAL CELL RESEARCH

Restricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway

(2017) Yuanlin He et al.   Cell Death & Disease

Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary

(2016) Hoon Jang et al.   JOURNAL OF PINEAL RESEARCH

Risks of conservative management in women with ovarian endometriomas undergoing IVF

(2015) Edgardo Somigliana et al.   HUMAN REPRODUCTION UPDATE

miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

(2015) Shicheng Su et al.   Nature Communications

Epidermal Growth Factor (EGF) Sustains In Vitro Primordial Follicle Viability by Enhancing Stromal Cell Proliferation via MAPK and PI3K Pathways in the Prepubertal, but Not Adult, Cat Ovary1

(2014) Mayako Fujihara et al.   BIOLOGY OF REPRODUCTION

Transforming Growth Factor-β Signaling Participates in the Maintenance of the Primordial Follicle Pool in the Mouse Ovary

(2014) Zheng-Pin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unique Temporal and Spatial Expression Patterns of IL-33 in Ovaries during Ovulation and Estrous Cycle Are Associated with Ovarian Tissue Homeostasis

(2014) C. I. Carlock et al.   JOURNAL OF IMMUNOLOGY

Immune regulation of ovarian development: programming by neonatal immune challenge

(2013) Luba Sominsky et al.   Frontiers in Neuroscience

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular contributions to early ovarian development: potential roles of VEGFA isoforms

(2012) Renee M. McFee et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Inflammation in Polycystic Ovary Syndrome: Underpinning of insulin resistance and ovarian dysfunction

(2011) Frank González   STEROIDS

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

(2009) D. Adhikari et al.   HUMAN MOLECULAR GENETICS

Oocyte-Specific Deletion of Pten in Mice Reveals a Stage-Specific Function of PTEN/PI3K Signaling in Oocytes in Controlling Follicular Activation

(2009) Krishna Jagarlamudi et al.   PLoS One

Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool

(2008) P. Reddy et al.   SCIENCE