Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy
Authors
Keywords
-
Journal
Bioactive Materials
Volume 16, Issue -, Pages 1-11
Publisher
Elsevier BV
Online
2022-03-04
DOI
10.1016/j.bioactmat.2022.02.029
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy
- (2021) Nina M. Muñoz et al. Journal for ImmunoTherapy of Cancer
- Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma
- (2021) Yifeng Xia et al. JOURNAL OF CONTROLLED RELEASE
- STING Agonists as Cancer Therapeutics
- (2021) Afsaneh Amouzegar et al. Cancers
- A Failure to Start: Aborted Activation of CAR T Cells in Chronic Lymphocytic Leukemia
- (2020) McKensie Collins et al. BLOOD
- Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy
- (2020) Xueguang Lu et al. Science Translational Medicine
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration
- (2020) Mohamed Wehbe et al. JOURNAL OF CONTROLLED RELEASE
- Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy
- (2019) Daniel Shae et al. Nature Nanotechnology
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- Addition of Low-Dose Decitabine to Anti–PD-1 Antibody Camrelizumab in Relapsed/Refractory Classical Hodgkin Lymphoma
- (2019) Jing Nie et al. JOURNAL OF CLINICAL ONCOLOGY
- Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy
- (2019) Anping Li et al. Journal of Hematology & Oncology
- Material design for lymph node drug delivery
- (2019) Alex Schudel et al. Nature Reviews Materials
- Cancer nanomedicine for combination cancer immunotherapy
- (2019) Jutaek Nam et al. Nature Reviews Materials
- STING pathway agonism as a cancer therapeutic
- (2019) Blake A. Flood et al. IMMUNOLOGICAL REVIEWS
- DNA sensing by the cGAS–STING pathway in health and disease
- (2019) Mona Motwani et al. NATURE REVIEWS GENETICS
- Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system
- (2019) Claire Lhuillier et al. Genome Medicine
- CAR-NK for tumor immunotherapy: Clinical transformation and future prospects
- (2019) Wenxiu Wang et al. CANCER LETTERS
- An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases
- (2019) Yang Liu et al. Nature Communications
- Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
- (2019) Kelsey E. Sivick et al. Cell Reports
- Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response
- (2019) Mireia Uribe-Herranz et al. JOURNAL OF CLINICAL INVESTIGATION
- Engineered nanomedicines with enhanced tumor penetration
- (2019) Jianxun Ding et al. Nano Today
- Protein Toxin Chaperoned by LRP-1-Targeted Virus-Mimicking Vesicles Induces High-Efficiency Glioblastoma Therapy In Vivo
- (2018) Yu Jiang et al. ADVANCED MATERIALS
- STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy
- (2018) David G. Leach et al. BIOMATERIALS
- Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
- (2018) Jeonghyun Ahn et al. CANCER CELL
- A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination
- (2018) Robert D. Junkins et al. JOURNAL OF CONTROLLED RELEASE
- The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
- (2018) Tuo Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Patients with melanoma treated with an anti-PD-1 antibody beyond RECIST progression: a US Food and Drug Administration pooled analysis
- (2018) Julia A Beaver et al. LANCET ONCOLOGY
- Irradiation Enhances Abscopal Anti-tumor Effects of Antigen-Specific Immunotherapy through Regulating Tumor Microenvironment
- (2018) Ming-Cheng Chang et al. MOLECULAR THERAPY
- A facile approach to enhance antigen response for personalized cancer vaccination
- (2018) Aileen Weiwei Li et al. NATURE MATERIALS
- Can innate immune system targets turn up the heat on 'cold' tumours?
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity
- (2018) Myunggi An et al. Nanoscale
- Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis
- (2018) Michäel Duruisseaux et al. Lancet Respiratory Medicine
- Long-term Clinical Outcomes and Biomarker Analyses of Atezolizumab Therapy for Patients With Metastatic Triple-Negative Breast Cancer
- (2018) Leisha A. Emens et al. JAMA Oncology
- Anti-PD-1 Antibody SHR-1210 Combined with Apatinib for Advanced Hepatocellular Carcinoma, Gastric, or Esophagogastric Junction Cancer: An Open-label, Dose Escalation and Expansion Study
- (2018) Jianming Xu et al. CLINICAL CANCER RESEARCH
- Granzyme B-loaded, cell-selective penetrating and reduction-responsive polymersomes effectively inhibit progression of orthotopic human lung tumor in vivo
- (2018) Weijing Yang et al. JOURNAL OF CONTROLLED RELEASE
- Boosting RNAi therapy for orthotopic glioblastoma with nontoxic brain-targeting chimaeric polymersomes
- (2018) Yanan Shi et al. JOURNAL OF CONTROLLED RELEASE
- Radiotherapy induces responses of lung cancer to CTLA-4 blockade
- (2018) Silvia C. Formenti et al. NATURE MEDICINE
- Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)
- (2018) Marcin Kowanetz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS is essential for the antitumor effect of immune checkpoint blockade
- (2017) Hua Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I Interferon in Chronic Virus Infection and Cancer
- (2017) Laura M. Snell et al. TRENDS IN IMMUNOLOGY
- A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice
- (2017) Jeremy B. Foote et al. Cancer Immunology Research
- Submicron-sized hydrogels incorporating cyclic dinucleotides for selective delivery and elevated cytokine release in macrophages
- (2016) Eunjoo Lee et al. Acta Biomaterialia
- Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas
- (2016) Jennifer E. Kim et al. CLINICAL CANCER RESEARCH
- The host STING pathway at the interface of cancer and immunity
- (2016) Leticia Corrales et al. JOURNAL OF CLINICAL INVESTIGATION
- Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial
- (2016) Anas Younes et al. LANCET ONCOLOGY
- Current Insights in Radiation Combination Therapies: Influence of Omics and Novel Targeted Agents in Defining New Concepts in Radiation Biology and Clinical Radiation Oncology
- (2016) Mansoor M. Ahmed et al. SEMINARS IN RADIATION ONCOLOGY
- Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors
- (2015) J. R. Baird et al. CANCER RESEARCH
- Intratumoral dendritic cells in the anti-tumor immune response
- (2015) Yang Liu et al. Cellular & Molecular Immunology
- From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy
- (2015) L. Deng et al. CLINICAL CANCER RESEARCH
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- Immunological Responses Triggered by Photothermal Therapy with Carbon Nanotubes in Combination with Anti-CTLA-4 Therapy to Inhibit Cancer Metastasis
- (2014) Chao Wang et al. ADVANCED MATERIALS
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles
- (2011) Sandy Vrignaud et al. BIOMATERIALS
- Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
- (2011) H. Cabral et al. Nature Nanotechnology
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody
- (2009) M. Z. Dewan et al. CLINICAL CANCER RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started