Alternatives to Antibiotics against Mycobacterium abscessus

Viruses to the rescue—Use of bacteriophage to treat resistant pulmonary infections

(2022) Alexandra Toporek et al.   CELL

Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

(2022) Jerry A. Nick et al.   CELL

2-Aminoimidazoles Inhibit Mycobacterium abscessus Biofilms in a Zinc-Dependent Manner

(2022) Juan M. Belardinelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vitro study of the effect of ALA-PDT on Mycobacterium abscessus and its antibiotic susceptibility

(2022) Chenda Yue et al.   Photodiagnosis and Photodynamic Therapy

Nebulized bacteriophage in a patient with refractory Mycobacterium abscessus lung disease

(2022) Rebekah M. Dedrick et al.   Open Forum Infectious Diseases

ALA_PDT Promotes Ferroptosis-Like Death of Mycobacterium abscessus and Antibiotic Sterilization via Oxidative Stress

(2022) Xiaoyu Wang et al.   Antioxidants

Phage Therapy of Mycobacterium Infections: Compassionate-use of Phages in Twenty Patients with Drug-Resistant Mycobacterial Disease

(2022) Rebekah M. Dedrick et al.   CLINICAL INFECTIOUS DISEASES

High-Throughput Screening Identifies Synthetic Peptides with Antibacterial Activity against Mycobacterium abscessus and Serum Stability

(2022) Natalie Iannuzo et al.   ACS Omega

A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

(2021) Komal Umashankar Rao et al.   Scientific Reports

Phage Therapy for Mycobacterium Abscessus and Strategies to Improve Outcomes

(2021) Abdolrazagh Hashemi Shahraki et al.   Microorganisms

Potent antibody-mediated neutralization limits bacteriophage treatment of a pulmonary Mycobacterium abscessus infection

(2021) Rebekah M. Dedrick et al.   NATURE MEDICINE

Designing a multi-epitope vaccine against Mycobacteroides abscessus by pangenome-reverse vaccinology

(2021) Hamza Arshad Dar et al.   Scientific Reports

Targeting Intracellular Mycobacteria Using Nanosized Niosomes Loaded with Antibacterial Agents

(2021) Yael Nicole Slavin et al.   Nanomaterials

Nanoparticulate β-Cyclodextrin with Gallium Tetraphenylporphyrin Demonstrates in Vitro and in Vivo Antimicrobial Efficacy against Mycobacteroides abscessus and Mycobacterium avium

(2021) Seoung-Ryoung Choi et al.   ACS Infectious Diseases

Mesenchymal Stem Cells and Tuberculosis: Clinical Challenges and Opportunities

(2021) Xueying Zhang et al.   Frontiers in Immunology

Assessment of in vitro activities of novel modified antimicrobial peptides against clarithromycin resistant Mycobacterium abscessus

(2021) Phantitra Sudadech et al.   PLoS One

Antibacterial peptide RP557 increases the antibiotic sensitivity of Mycobacterium abscessus by inhibiting biofilm formation

(2021) Bing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus

(2020) Matt D. Johansen et al.   NATURE REVIEWS MICROBIOLOGY

Successful treatment of atypical mycobacteriosis of the scalp with photodynamic therapy

(2020) Alessia Barisani et al.   Dermatologic Therapy

Antimicrobial peptides against drug resistant Mycobacterium abscessus

(2020) Joas L. da Silva et al.   RESEARCH IN MICROBIOLOGY

Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress

(2020) Bo-Ram Kim et al.   PLoS Pathogens

Metal center ion effects on photoinactivating rapidly growing mycobacteria using water-soluble tetra-cationic porphyrins

(2020) Kevim Bordignon Guterres et al.   BIOMETALS

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline

(2020) Charles L Daley et al.   CLINICAL INFECTIOUS DISEASES

A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential

(2020) Vincent Le Moigne et al.   Frontiers in Cellular and Infection Microbiology

Actinobacteriophages: Genomics, Dynamics, and Applications

(2020) Graham F. Hatfull   Annual Review of Virology

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Challenges and Controversies in Human Mesenchymal Stem Cell Therapy

(2019) Barbara Lukomska et al.   Stem Cells International

Preliminary evaluation of the positively and negatively charge effects of tetra-substituted porphyrins on photoinactivation of rapidly growing mycobacteria

(2019) Kevim Bordignon Guterres et al.   TUBERCULOSIS

Inhibition of Mycobacterium abscessus, M. chelonae, and M. fortuitum biofilms by Methylobacterium sp

(2019) Marta García-Coca et al.   JOURNAL OF ANTIBIOTICS

Biofilms of Mycobacterium abscessus complex can be sensitized to antibiotics by disaggregation and oxygenation

(2019) Mette Kolpen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

(2019) Violaine Dubois et al.   PLoS Pathogens

Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells

(2019) Lyndah Chow et al.   Stem Cells Translational Medicine

PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus

(2019) Frantiescoli Anversa Dimer et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mycobacterium abscessus Smooth and Rough Morphotypes Form Antimicrobial-Tolerant Biofilm Phenotypes but Are Killed by Acetic Acid

(2018) Gillian Clary et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice

(2018) Seoung-ryoung Choi et al.   MOLECULAR PHARMACEUTICS

Identification of genes required forMycobacterium abscessusgrowth in vivo with a prominent role of the ESX-4 locus

(2018) Laura Laencina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycopeptidolipids, a Double-Edged Sword of the Mycobacterium abscessus Complex

(2018) Ana Victoria Gutiérrez et al.   Frontiers in Microbiology

Geographic Distribution of Nontuberculous Mycobacteria Isolated from Clinical Specimens: A Systematic Review

(2018) Sanne Zweijpfenning et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Nontuberculous Mycobacteria in Cystic Fibrosis

(2018) Patrick Flume et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

The Role of Antibiotic-Target-Modifying and Antibiotic-Modifying Enzymes in Mycobacterium abscessus Drug Resistance

(2018) Sakshi Luthra et al.   Frontiers in Microbiology

Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches

(2018) Jennifer R. Honda et al.   Frontiers in Microbiology

MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family

(2018) Violaine Dubois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of the antimicrobial activity of the mastoparan Polybia-MPII isolated from venom of the social wasp Pseudopolybia vespiceps testacea (Vespidae, Hymenoptera)

(2017) Juliana C. Silva et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antibiofilm activity of nanoemulsions of Cymbopogon flexuosus against rapidly growing mycobacteria

(2017) Grazielle Guidolin Rossi et al.   MICROBIAL PATHOGENESIS

Antimicrobial peptides secreted by equine mesenchymal stromal cells inhibit the growth of bacteria commonly found in skin wounds

(2017) Rebecca M. Harman et al.   Stem Cell Research & Therapy

Non-disulfide-Bridge Peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits the Growth of Mycobacterium abscessus subsp. massiliense

(2017) Monalisa M. Trentini et al.   Frontiers in Microbiology

Mycobacterium abscessus ᴅ-alanyl-ᴅ-alanine dipeptidase induces the maturation of dendritic cells and promotes Th1-biased immunity

(2016) Seung Jun Lee et al.   BMB Reports

MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection

(2016) Vincent Le Moigne et al.   INFECTION AND IMMUNITY

Emended description of Mycobacterium abscessus, Mycobacterium abscessus subsp. abscessus and Mycobacterium abscessus subsp. bolletii and designation of Mycobacterium abscessus subsp. massiliense comb. nov.

(2016) Enrico Tortoli et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

A Novel Therapeutic Approach Using Mesenchymal Stem Cells to Protect Against Mycobacterium abscessus

(2016) Jong-Seok Kim et al.   STEM CELLS

Antimicrobial Properties of Mesenchymal Stem Cells: Therapeutic Potential for Cystic Fibrosis Infection, and Treatment

(2016) Morgan T. Sutton et al.   Stem Cells International

Antimycobacterial Activity of a New Peptide Polydim-I Isolated from Neotropical Social Wasp Polybia dimorpha

(2016) Rogerio Coutinho das Neves et al.   PLoS One

Essential Engagement of Toll-Like Receptor 2 in Initiation of Early Protective Th1 Response against Rough Variants of Mycobacterium abscessus

(2015) Jong-Seok Kim et al.   INFECTION AND IMMUNITY

Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members

(2015) Audrey Bernut et al.   MOLECULAR MICROBIOLOGY

Mycobacterium abscessus Morphotype Comparison in a Murine Model

(2015) Lindsay J. Caverly et al.   PLoS One

Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: The Mycobacterium abscessus model

(2015) Vincent Le Moigne et al.   VACCINE

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

Importance of Reciprocal Balance of T Cell Immunity in Mycobacterium abscessus Complex Lung Disease

(2014) Su-Young Kim et al.   PLoS One

Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial

(2014) Aliaksandr Skrahin et al.   Lancet Respiratory Medicine

Secretion of immunoregulatory cytokines by mesenchymal stem cells

(2014) Dobroslav Kyurkchiev   World Journal of Stem Cells

Immunobiology of mesenchymal stem cells

(2013) S Ma et al.   CELL DEATH AND DIFFERENTIATION

Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation

(2013) Hiroshi Wakao et al.   Cell Stem Cell

Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistentMycobacterium abscessus

(2013) Alexandre Pawlik et al.   MOLECULAR MICROBIOLOGY

CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis

(2013) B. Das et al.   Science Translational Medicine

Prevalence of Nontuberculous Mycobacterial Lung Disease in U.S. Medicare Beneficiaries

(2012) Jennifer Adjemian et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mesenchymal Stromal Cells Improve Survival During Sepsis in the Absence of Heme Oxygenase-1: The Importance of Neutrophils

(2012) Sean R. R. Hall et al.   STEM CELLS

Mesenchymal stem cells enhance survival and bacterial clearance in murineEscherichia colipneumonia

(2012) Naveen Gupta et al.   THORAX

Clinical trials for stem cell therapies

(2011) Alan Trounson et al.   BMC Medicine

Clinical and Microbiologic Outcomes in Patients Receiving Treatment for Mycobacterium abscessus Pulmonary Disease

(2011) Julie Jarand et al.   CLINICAL INFECTIOUS DISEASES

Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis

(2011) E. M. Bruscia et al.   JOURNAL OF IMMUNOLOGY

Antibacterial activities of dendritic amphiphiles against nontuberculous mycobacteria

(2011) Joseph O. Falkinham et al.   TUBERCULOSIS

Increasing reports of non-tuberculous mycobacteria in England, Wales and Northern Ireland, 1995-2006

(2010) Jonathan E Moore et al.   BMC PUBLIC HEALTH

Bone Marrow Mesenchymal Stromal Cells Attenuate Organ Injury Induced by LPS and Burn

(2010) Hiroshi Yagi et al.   CELL TRANSPLANTATION

Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37

(2010) Anna Krasnodembskaya et al.   STEM CELLS

Interleukin-22-Producing Natural Killer Cells and Lymphoid Tissue Inducer-like Cells in Mucosal Immunity

(2009) Marco Colonna   IMMUNITY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Photodynamic therapy for localized infections—State of the art

(2009) Tianhong Dai et al.   Photodiagnosis and Photodynamic Therapy

Biology and clinical relevance of granulysin

(2009) A. M. Krensky et al.   TISSUE ANTIGENS

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2and LXA4in the induction of macrophage death

(2008) Minjian Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE