Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease

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Title
Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 59, Issue 23, Pages 10435-10450
Publisher
American Chemical Society (ACS)
Online
2016-11-18
DOI
10.1021/acs.jmedchem.6b00307

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