Muscle Amino Acid and Adenine Nucleotide Metabolism during Exercise and in Liver Cirrhosis: Speculations on How to Reduce the Harmful Effects of Ammonia

Drug-associated hyperammonaemia: a Bayesian analysis of the WHO Pharmacovigilance Database

(2022) Alexander Balcerac et al.   Annals of Intensive Care

Ammonia Removal by Metabolic Scavengers for the Prevention and Treatment of Hepatic Encephalopathy in Cirrhosis

(2021) Roger F. Butterworth   DRUGS IN R&D

The Role of Skeletal Muscle in The Pathogenesis of Altered Concentrations of Branched-Chain Amino Acids (Valine, Leucine, and Isoleucine) in Liver Cirrhosis, Diabetes, and Other Diseases

(2021) M Holeček   PHYSIOLOGICAL RESEARCH

Effect of Glutamine Supplementation on Muscular Damage Biomarkers in Professional Basketball Players

(2021) Alfredo Córdova-Martínez et al.   Nutrients

Relationship between the incidence of non-hepatic hyperammonemia and the prognosis of patients in the intensive care unit

(2020) Zhi-Peng Yao et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Muscle wasting and branched-chain amino acid, alpha-ketoglutarate, and ATP depletion in a rat model of liver cirrhosis

(2019) Milan Holeček et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Efficacy of orally administered sodium benzoate and sodium phenylbutyrate in dogs with congenital portosystemic shunts

(2019) Giora van Straten et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

Keto analogues and amino acid supplementation and its effects on ammonaemia during extenuating endurance exercise in ketogenic diet-fed rats

(2018) Rogério T. Ferreira et al.   BRITISH JOURNAL OF NUTRITION

Effects of branched-chain amino acids on muscles under hyperammonemic conditions

(2018) Milan Holeček et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis

(2017) Avinash Kumar et al.   HEPATOLOGY

Acute effects of phenylbutyrate on glutamine, branched-chain amino acid and protein metabolism in skeletal muscles of rats

(2017) Milan Holecek et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Hyperammonemia results in reduced muscle function independent of muscle mass

(2016) John McDaniel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Phenylbutyrate exerts adverse effects on liver regeneration and amino acid concentrations in partially hepatectomized rats

(2016) Milan Holecek et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress

(2016) Gangarao Davuluri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Alterations in protein and amino acid metabolism in rats fed a branched-chain amino acid- or leucine-enriched diet during postprandial and postabsorptive states

(2016) Milan Holecek et al.   Nutrition & Metabolism

The Influence of Oral L-Glutamine Supplementation on Muscle Strength Recovery and Soreness Following Unilateral Knee Extension Eccentric Exercise

(2015) Zachary Legault et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Glutamine deficiency in extracellular fluid exerts adverse effects on protein and amino acid metabolism in skeletal muscle of healthy, laparotomized, and septic rats

(2014) Milan Holecek et al.   AMINO ACIDS

Evidence of a vicious cycle in glutamine synthesis and breakdown in pathogenesis of hepatic encephalopathy–therapeutic perspectives

(2013) Milan Holecek   METABOLIC BRAIN DISEASE

Branched-chain amino acids and muscle ammonia detoxification in cirrhosis

(2013) Gitte Dam et al.   METABOLIC BRAIN DISEASE

Ammonium metabolism in humans

(2012) Maria M. Adeva et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Effects of Diets Supplemented with Branched-Chain Amino Acids on the Performance and Fatigue Mechanisms of Rats Submitted to Prolonged Physical Exercise

(2012) Gina Falavigna et al.   Nutrients

Severe hyperammonaemia in adults not explained by liver disease

(2012) V. Walker   ANNALS OF CLINICAL BIOCHEMISTRY

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

(2011) Gitte Dam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells

(2011) Kang Yao et al.   AMINO ACIDS

Keto analogue and amino acid supplementation affects the ammonaemia response during exercise under ketogenic conditions

(2011) Eduardo Seixas Prado et al.   BRITISH JOURNAL OF NUTRITION

Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle

(2010) Milan Holecek et al.   AMINO ACIDS

Acute supplementation with keto analogues and amino acids in rats during resistance exercise

(2010) Rosemeire Dantas de Almeida et al.   BRITISH JOURNAL OF NUTRITION

Pharmacotherapy for Hepatic Encephalopathy

(2010) Paula V. Phongsamran et al.   DRUGS

Effects of β-hydroxy-β-methylbutyrate treatment in different types of skeletal muscle of intact and septic rats

(2010) Miroslav Kovarik et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

EFFECT OF EXERCISE ON GLUTAMINE SYNTHESIS AND TRANSPORT IN SKELETAL MUSCLE FROM RATS

(2009) Ronaldo VT dos Santos et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Aspartate as an Ergogenic Supplement

(2009) François Trudeau   SPORTS MEDICINE

Effect of beta-hydroxy-beta-methylbutyrate (HMB) on protein metabolism in whole body and in selected tissues

(2008) M. Holecek et al.   FOOD AND CHEMICAL TOXICOLOGY

Can Glutamine Enable the Critically Ill to Cope Better With Infection?

(2008) Gil Hardy et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION