Mycobacterium abscessus Mutants with a Compromised Functional Link between the Type VII ESX-3 System and an Iron Uptake Mechanism Reliant on an Unusual Mycobactin Siderophore

Type VII secretion systems: structure, functions and transport models

(2021) Angel Rivera-Calzada et al.   NATURE REVIEWS MICROBIOLOGY

Genome-Wide Essentiality Analysis of Mycobacterium abscessus by Saturated Transposon Mutagenesis and Deep Sequencing

(2021) Dalin Rifat et al.   mBio

Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes

(2020) Paulina Knobloch et al.   CELLULAR MICROBIOLOGY

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis

(2020) Lei Zhang et al.   PLoS Pathogens

Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth

(2020) William C. Budell et al.   MicrobiologyOpen

The Rise of Non-Tuberculosis Mycobacterial Lung Disease

(2020) Champa N. Ratnatunga et al.   Frontiers in Immunology

Architecture of the mycobacterial type VII secretion system

(2019) Nikolaos Famelis et al.   NATURE

The structure of the endogenous ESX-3 secretion system

(2019) Nicole Poweleit et al.   eLife

Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents

(2018) Glennon V. Bythrow et al.   BIOCHEMISTRY

Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems

(2018) Anne T. Tuukkanen et al.   JOURNAL OF MOLECULAR BIOLOGY

Total Synthesis of the Proposed Structure of Mycobactin J

(2018) Chiranjit Ghosh et al.   ORGANIC LETTERS

Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection

(2017) Yi Sak Kim et al.   MICROBES AND INFECTION

Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

(2017) Michael A. DeJesus et al.   mBio

First case report of chronic pulmonary lung disease caused byMycobacterium abscessusin two immunocompetent patients in Saudi Arabia

(2017) Bright Varghese et al.   ANNALS OF SAUDI MEDICINE

The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systems

(2016) Mae Newton-Foot et al.   BMC EVOLUTIONARY BIOLOGY

Mycobacterial Pan-Genome Analysis Suggests Important Role of Plasmids in the Radiation of Type VII Secretion Systems

(2016) Emilie Dumas et al.   Genome Biology and Evolution

Emended description of Mycobacterium abscessus, Mycobacterium abscessus subsp. abscessus and Mycobacterium abscessus subsp. bolletii and designation of Mycobacterium abscessus subsp. massiliense comb. nov.

(2016) Enrico Tortoli et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

ESX secretion systems: mycobacterial evolution to counter host immunity

(2016) Matthias I. Gröschel et al.   NATURE REVIEWS MICROBIOLOGY

Separable roles forMycobacterium tuberculosisESX-3 effectors in iron acquisition and virulence

(2016) JoAnn M. Tufariello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipidomic Analysis Links Mycobactin Synthase K to Iron Uptake and Virulence in M. tuberculosis

(2015) Cressida A. Madigan et al.   PLoS Pathogens

Biosynthesis of mycobacterial lipids by polyketide synthases and beyond

(2014) Luis E. N. Quadri   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Targeting Type VII/ESX Secretion Systems for Development of Novel Antimycobacterial Drugs

(2014) Daria Bottai et al.   CURRENT PHARMACEUTICAL DESIGN

Protein as Chemical Cue: Non-Nutritional Growth Enhancement by Exogenous Protein in Pseudomonas putida KT2440

(2014) Hiren Joshi et al.   PLoS One

Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion

(2014) D. C. Ekiert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition

(2014) M. S. Siegrist et al.   mBio

Pharmacokinetic andIn VivoEfficacy Studies of the Mycobactin Biosynthesis Inhibitor Salicyl-AMS in Mice

(2013) Shichun Lun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries

(2013) Michael A. DeJesus et al.   BIOINFORMATICS

Comparative Genomic Insights Into the Biosynthesis and Regulation of Mycobacterial Siderophores

(2013) Wu Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model–based analyses of transposon-insertion sequencing data

(2013) Michael C. Chao et al.   NUCLEIC ACIDS RESEARCH

The ESX-3 Secretion System Is Necessary for Iron and Zinc Homeostasis in Mycobacterium tuberculosis

(2013) Agnese Serafini et al.   PLoS One

Sequence-Defined Transposon Mutant Library of Burkholderia thailandensis

(2013) L. A. Gallagher et al.   mBio

Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria

(2012) Jakko van Ingen et al.   DRUG RESISTANCE UPDATES

Mycobacterium abscessus: a new antibiotic nightmare

(2012) R. Nessar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

OrtholugeDB: a bacterial and archaeal orthology resource for improved comparative genomic analysis

(2012) Matthew D. Whiteside et al.   NUCLEIC ACIDS RESEARCH

Optimized compatible set of BioBrick™ vectors for metabolic pathway engineering

(2011) Jacob E. Vick et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide–polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis

(2011) Julian A. Ferreras et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mutational and Phylogenetic Analyses of the Mycobacterial mbt Gene Cluster

(2011) S. S. Chavadi et al.   JOURNAL OF BACTERIOLOGY

Inactivation oftesAReduces Cell Wall Lipid Production and Increases Drug Susceptibility in Mycobacteria

(2011) Sivagami Sundaram Chavadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Structure of theMycobacterium tuberculosisEsxG·EsxH Complex

(2011) Dariush Ilghari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis

(2011) Kari A Sweeney et al.   NATURE MEDICINE

Clinical Significance of Differentiation ofMycobacterium massiliensefromMycobacterium abscessus

(2010) Won-Jung Koh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapidly Growing Mycobacteria Infection in Patients with Cancer

(2010) Gil Redelman‐Sidi et al.   CLINICAL INFECTIOUS DISEASES

Protein export systems ofMycobacterium tuberculosis: novel targets for drug development?

(2010) Meghan E Feltcher et al.   Future Microbiology

Taking phage integration to the next level as a genetic tool for mycobacteria

(2010) Jason Huff et al.   GENE

An improved counterselectable marker system for mycobacterial recombination using galK and 2-deoxy-galactose

(2010) Daniel Barkan et al.   GENE

Mycobacterium abscessus: a new player in the mycobacterial field

(2010) Halima Medjahed et al.   TRENDS IN MICROBIOLOGY

Transcriptional analysis of ESAT-6 cluster 3 in Mycobacterium smegmatis

(2009) Anna Maciąg et al.   BMC MICROBIOLOGY

Characterization of a Mycobacterium tuberculosis ESX-3 Conditional Mutant: Essentiality and Rescue by Iron and Zinc

(2009) A. Serafini et al.   JOURNAL OF BACTERIOLOGY

Identification and functional characterization of the iron-dependent regulator (IdeR) of Mycobacterium avium subsp. paratuberculosis

(2009) H. K. Janagama et al.   MICROBIOLOGY-SGM

Non Mycobacterial Virulence Genes in the Genome of the Emerging Pathogen Mycobacterium abscessus

(2009) Fabienne Ripoll et al.   PLoS One

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Genetic Nomenclature for Type VII Secretion Systems

(2009) Wilbert Bitter et al.   PLoS Pathogens

Molecular Features Governing the Stability and Specificity of Functional Complex Formation byMycobacterium tuberculosisCFP-10/ESAT-6 Family Proteins

(2008) Kirsty L. Lightbody et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A defined transposon mutant library and its use in identifying motility genes in Vibrio cholerae

(2008) D. E. Cameron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mycobacterium tuberculosis IdeR is a dual functional regulator that controls transcription of genes involved in iron acquisition, iron storage and survival in macrophages

(2003) Benjamin Gold et al.   MOLECULAR MICROBIOLOGY