Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket

Title
Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 59, Issue 22, Pages 10163-10175
Publisher
American Chemical Society (ACS)
Online
2016-09-30
DOI
10.1021/acs.jmedchem.6b00927

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