Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 59, Issue 7, Pages 3034-3045Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jmedchem.5b01657
Keywords
-
Categories
Ask authors/readers for more resources
The discovery of a highly potent and selective small molecule inhibitor 9 for in vitro target validation of MNK1/2 kinases is described. The aminopyrazine benzimidazole series was derived from an HTS hit and optimized by utilization of a docking model, conformation analysis, and binding pocket comparison against antitargets.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available