Antioxidant Response in Human X-Linked Adrenoleukodystrophy Fibroblasts

The Role of Oxidative Stress and Inflammation in X-Link Adrenoleukodystrophy

(2022) Jiayu Yu et al.   Frontiers in Nutrition

Lipid Metabolism and Ferroptosis

(2021) Ji-Yoon Lee et al.   Biology-Basel

How the brain fights fatty acids’ toxicity

(2021) Peter Schönfeld et al.   NEUROCHEMISTRY INTERNATIONAL

The diverse functionality of NQO1 and its roles in redox control

(2021) David Ross et al.   Redox Biology

Lipid Metabolism in Ferroptosis

(2021) Zhi Lin et al.   Advanced Biology

X‐linked adrenoleukodystrophy: Pathology, pathophysiology, diagnostic testing, newborn screening and therapies

(2020) Bela R. Turk et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress, a Crossroad Between Rare Diseases and Neurodegeneration

(2020) Carmen Espinós et al.   Antioxidants

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

(2019) Pengxu Lei et al.   Frontiers in Physiology

GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis

(2019) Giovanni C. Forcina et al.   PROTEOMICS

Ferroptosis and Brain Injury

(2019) Leslie Magtanong et al.   DEVELOPMENTAL NEUROSCIENCE

Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model

(2019) Margaux Doria et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study

(2019) Carlos Casasnovas et al.   Neurotherapeutics

Targeting NRF2 for the Treatment of Friedreich’s Ataxia: A Comparison among Drugs

(2019) Sara Petrillo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy

(2017) Florian Eichler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy

(2016) Nathalie Launay et al.   ACTA NEUROPATHOLOGICA

Quantitative MRI of the spinal cord and brain in adrenomyeloneuropathy:in vivoassessment of structural changes

(2016) Antonella Castellano et al.   BRAIN

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new multiplex method for the diagnosis of peroxisomal disorders allowing simultaneous determination of plasma very-long-chain fatty acids, phytanic, pristanic, docosahexaenoic and bile acids by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry

(2016) Michela Semeraro et al.   CLINICA CHIMICA ACTA

Adrenoleukodystrophy – neuroendocrine pathogenesis and redefinition of natural history

(2016) Stephan Kemp et al.   Nature Reviews Endocrinology

Oxidative Stress in Patients with X-Linked Adrenoleukodystrophy

(2015) Marion Deon et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration

(2015) Stéphane Fourcade et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy

(2014) Nathalie Launay et al.   ACTA NEUROPATHOLOGICA

Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy

(2013) J. López-Erauskin et al.   HUMAN MOLECULAR GENETICS

Impaired Very Long-chain Acyl-CoA β-Oxidation in Human X-linked Adrenoleukodystrophy Fibroblasts Is a Direct Consequence of ABCD1 Transporter Dysfunction

(2013) Christoph Wiesinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione imbalance in patients with X-linked adrenoleukodystrophy

(2013) Sara Petrillo et al.   MOLECULAR GENETICS AND METABOLISM

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

(2012) Elena Galea et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

(2012) Jone López-Erauskin et al.   BRAIN

Lipid peroxidation triggers neurodegeneration: A redox proteomics view into the Alzheimer disease brain

(2012) Rukhsana Sultana et al.   FREE RADICAL BIOLOGY AND MEDICINE

X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management

(2012) Marc Engelen et al.   Orphanet Journal of Rare Diseases

Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy

(2011) Jone López-Erauskin et al.   ANNALS OF NEUROLOGY

Oxidative Damage Compromises Energy Metabolism in the Axonal Degeneration Mouse Model of X-Adrenoleukodystrophy

(2011) Jorge Galino et al.   ANTIOXIDANTS & REDOX SIGNALING

Outcomes after allogeneic hematopoietic cell transplantation for childhood cerebral adrenoleukodystrophy: the largest single-institution cohort report

(2011) W. P. Miller et al.   BLOOD

Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

(2011) Oksana Ivashchenko et al.   MOLECULAR BIOLOGY OF THE CELL

Pathomechanisms Underlying X-Adrenoleukodystrophy: A Three-Hit Hypothesis

(2010) Inderjit Singh et al.   BRAIN PATHOLOGY

Plasmalogens participate in very-long-chain fatty acid-induced pathology

(2008) P. Brites et al.   BRAIN

The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters

(2008) Carlo W. T. van Roermund et al.   FASEB JOURNAL

Toxic effects of X-linked adrenoleukodystrophy-associated, very long chain fatty acids on glial cells and neurons from rat hippocampus in culture

(2008) S. Hein et al.   HUMAN MOLECULAR GENETICS

Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

(2008) S. Fourcade et al.   HUMAN MOLECULAR GENETICS

Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin

(2008) Mushfiquddin Khan et al.   JOURNAL OF NEUROCHEMISTRY