Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

Regression of Liver Steatosis Following Phosphatidylcholine Administration: A Review of Molecular and Metabolic Pathways Involved

(2022) D. Osipova et al.   Frontiers in Pharmacology

Micronucleated erythrocytes in peripheral blood from neonate rats fed by nursing mothers exposed to X‐rays

(2021) Alejandro Solórzano‐Meléndez et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner

(2020) Karthickeyan Chella Krishnan et al.   Cellular and Molecular Gastroenterology and Hepatology

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

(2020) Olivier Govaere et al.   Science Translational Medicine

Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function

(2019) Zhengtao Liu et al.   METABOLIC ENGINEERING

Liver and Steroid Hormones—Can a Touch of p53 Make a Difference?

(2019) Meital Charni-Natan et al.   Frontiers in Endocrinology

Cardiovascular Risk in Non-Alcoholic Fatty Liver Disease: Mechanisms and Therapeutic Implications

(2019) Claudio Tana et al.   International Journal of Environmental Research and Public Health

Resveratrol alleviates non-alcoholic fatty liver disease through epigenetic modification of the Nrf2 signaling pathway

(2019) Hossein Hosseini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice

(2018) Uduak S. Udoh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease

(2018) Karthickeyan Chella Krishnan et al.   Cell Systems

Broad Views of Non-alcoholic Fatty Liver Disease

(2018) Adil Mardinoglu et al.   Cell Systems

Circadian clocks and insulin resistance

(2018) Dirk Jan Stenvers et al.   Nature Reviews Endocrinology

Network analyses identify liver‐specific targets for treating liver diseases

(2017) Sunjae Lee et al.   Molecular Systems Biology

Lipid droplets and liver disease: from basic biology to clinical implications

(2017) Nina L. Gluchowski et al.   Nature Reviews Gastroenterology & Hepatology

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

Pathophysiology and Mechanisms of Nonalcoholic Fatty Liver Disease

(2016) Joel T. Haas et al.   Annual Review of Physiology

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

The Epigenetic Drug 5-Azacytidine Interferes with Cholesterol and Lipid Metabolism

(2014) Steve Poirier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonalcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine

(2013) Bianca M. Arendt et al.   Applied Physiology Nutrition and Metabolism

Enriching the gene set analysis of genome-wide data by incorporating directionality of gene expression and combining statistical hypotheses and methods

(2013) Leif Väremo et al.   NUCLEIC ACIDS RESEARCH

AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells

(2012) Angelo Cerbone et al.   PPAR Research

Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

(2011) Keisuke Kakisaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY