T3 levels and thyroid hormone signaling

Primary hypothyroidism and quality of life

(2022) Laszlo Hegedüs et al.   Nature Reviews Endocrinology

Using Single-Cell RNA-Seq Data to Trace Tissue Cells Responsive to Thyroid Hormones

(2021) Liang Hu et al.   Frontiers in Endocrinology

Single-cell transcriptome profiling of thyroid hormone effectors in the human fetal neocortex: expression of SLCO1C1, DIO2, and THRB in specific cell types

(2021) Diego Diez et al.   THYROID

Resting energy expenditure in obese women with primary hypothyroidism and appropriate levothyroxine replacement therapy

(2020) Emanuele Muraca et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Screening for New Markers to Assess Thyroid Hormone Action by OMICs Analysis of Human Samples

(2020) Nele Friedrich et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Cardiac foetal reprogramming: a tool to exploit novel treatment targets for the failing heart

(2020) A. Pol et al.   JOURNAL OF INTERNAL MEDICINE

Nongenomic Actions of Thyroid Hormone: the Integrin Component

(2020) Paul J Davis et al.   PHYSIOLOGICAL REVIEWS

Identification of a novel mutation in CRYM in a Chinese family with hearing loss using whole‑exome sequencing

(2020) Min Wang et al.   Experimental and Therapeutic Medicine

Evidence Based Use of LT4/LT3 Combinations in Treating Hypothyroidism: A Consensus Document

(2020) jacqueline Jonklaas et al.   THYROID

Paradigms of Dynamic Control of Thyroid Hormone Signaling

(2019) Antonio C Bianco et al.   ENDOCRINE REVIEWS

Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism: A Systematic Review and Meta-Analysis

(2018) Elizabeth A McAninch et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pathophysiological relevance of deiodinase polymorphism

(2018) Antonio C. Bianco et al.   Current Opinion in Endocrinology Diabetes and Obesity

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

(2018) Sungro Jo et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue thyroid hormone metabolism is differentially regulated during illness in mice

(2017) Anita Boelen et al.   JOURNAL OF ENDOCRINOLOGY

Is the Intrinsic Genomic Activity of Thyroxine Relevant In Vivo? Effects on Gene Expression in Primary Cerebrocortical and Neuroblastoma Cells

(2017) Pilar Gil-Ibáñez et al.   THYROID

Myocardial Inactivation of Thyroid Hormones in Patients with Aortic Stenosis

(2017) Bruno S. Paolino et al.   THYROID

Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice

(2016) Barbara M. L. C. Bocco et al.   ENDOCRINOLOGY

Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography–mass spectrometry method

(2016) Meri De Angelis et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Is a Normal TSH Synonymous With “Euthyroidism” in Levothyroxine Monotherapy?

(2016) Sarah J. Peterson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of Levothyroxine Replacement or Suppressive Therapy on Energy Expenditure and Body Composition

(2016) Mary H. Samuels et al.   THYROID

Inherited defects of thyroxine-binding proteins

(2015) Theodora Pappa et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

(2015) Joao Pedro Werneck de Castro et al.   JOURNAL OF CLINICAL INVESTIGATION

Thyroid hormone transporters—functions and clinical implications

(2015) Juan Bernal et al.   Nature Reviews Endocrinology

The Astrocyte: Powerhouse and Recycling Center

(2015) Bruno Weber et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling

(2015) Lars Grøntved et al.   Nature Communications

Thyroid function in critically ill patients

(2015) Eric Fliers et al.   Lancet Diabetes & Endocrinology

The 5′-Deiodinases Are Not Essential for the Fasting-Induced Decrease in Circulating Thyroid Hormone Levels in Male Mice: Possible Roles for the Type 3 Deiodinase and Tissue Sequestration of Hormone

(2014) Valerie Anne Galton et al.   ENDOCRINOLOGY

Maternal Inheritance of an Inactive Type III Deiodinase Gene Allele Affects Mouse Pancreatic β-Cells and Disrupts Glucose Homeostasis

(2014) Mayrin C. Medina et al.   ENDOCRINOLOGY

Quantification of Thyroxine and 3,5,3′-Triiodo-Thyronine in Human and Animal Hearts by a Novel Liquid Chromatography-Tandem Mass Spectrometry Method

(2014) A. Saba et al.   HORMONE AND METABOLIC RESEARCH

Mutations of the Thyroid Hormone Transporter MCT8 Cause Prenatal Brain Damage and Persistent Hypomyelination

(2014) Daniela López-Espíndola et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Thyroid hormone receptors and resistance to thyroid hormone disorders

(2014) Tânia M. Ortiga-Carvalho et al.   Nature Reviews Endocrinology

Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement

(2014) Jacqueline Jonklaas et al.   THYROID

Thyroid Hormone Action: Astrocyte–Neuron Communication

(2014) Beatriz Morte et al.   Frontiers in Endocrinology

TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy

(2012) Mitsuru Ito et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients

(2011) Damiano Gullo et al.   PLoS One

Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine

(2010) Alessandro Saba et al.   ENDOCRINOLOGY

Thyroid hormone receptors are down-regulated in skeletal muscle of patients with non-thyroidal illness syndrome secondary to non-septic shock

(2010) J Lado-Abeal et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Paracrine signaling by glial cell–derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

(2010) Beatriz C.G. Freitas et al.   JOURNAL OF CLINICAL INVESTIGATION

Defining the Roles of the Iodothyronine Deiodinases: Current Concepts and Challenges

(2009) Donald L. St. Germain et al.   ENDOCRINOLOGY

Common Variation in theDIO2Gene Predicts Baseline Psychological Well-Being and Response to Combination Thyroxine Plus Triiodothyronine Therapy in Hypothyroid Patients

(2009) Vijay Panicker et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification of molecular mechanisms related to nonthyroidal illness syndrome in skeletal muscle and adipose tissue from patients with septic shock

(2007) Alfonso Rodriguez-Perez et al.   CLINICAL ENDOCRINOLOGY