Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2

The EMT-induced lncRNA NR2F1-AS1 positively modulates NR2F1 expression and drives gastric cancer via miR-29a-3p/VAMP7 axis

(2022) Dandan Li et al.   Cell Death & Disease

FGF-2 signaling in nasopharyngeal carcinoma modulates pericyte-macrophage crosstalk and metastasis

(2022) Yujie Wang et al.   JCI Insight

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MiRNA‐194 predicts favorable prognosis in gastric cancer and inhibits gastric cancer cell growth by targeting CCND1

(2021) Jingjie Wang et al.   FEBS Open Bio

Nomograms to Predict the Density of Tumor-Infiltrating Lymphocytes in Patients With High-Grade Serous Ovarian Cancer

(2021) Danian Dai et al.   Frontiers in Oncology

High Expression of PRSS3 Indicates Unfavorable Clinical Outcomes in Colon Adenocarcinoma

(2021) Quanyi Zhang et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Co-culturing polarized M2 Thp-1-derived macrophages enhance stemness of lung adenocarcinoma A549 cells

(2021) Xiaocheng Zhang et al.   Annals of Translational Medicine

New insights into M1/M2 macrophages: key modulators in cancer progression

(2021) Jiuyang Liu et al.   Cancer Cell International

The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA–RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis

(2021) Dandan Li et al.   ONCOGENE

Heparin-Binding Protein 17/Fibroblast Growth Factor-Binding Protein-1 Knockout Inhibits Proliferation and Induces Differentiation of Squamous Cell Carcinoma Cells

(2021) Tomoaki Shintani et al.   Cancers

Tumor-Associated Macrophages: Recent Insights and Therapies

(2020) Jiawei Zhou et al.   Frontiers in Oncology

Evaluating the Polarization of Tumor-Associated Macrophages Into M1 and M2 Phenotypes in Human Cancer Tissue: Technicalities and Challenges in Routine Clinical Practice

(2020) Sharmilla Devi Jayasingam et al.   Frontiers in Oncology

FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy

(2020) Jae Hong Im et al.   Nature Communications

Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment

(2020) Kaiyue Wu et al.   Frontiers in Immunology

S100 calcium‐binding protein A9 from tumor‐associated macrophage enhances cancer stem cell‐like properties of hepatocellular carcinoma

(2020) Ran Wei et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-Associated Macrophages in Tumor Immunity

(2020) Yueyun Pan et al.   Frontiers in Immunology

A critical review on marine serine protease and its inhibitors: A new wave of drugs?

(2020) Noora Barzkar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

(2019) Honghai Ma et al.   Scientific Reports

High‐level expression of PRSS3 correlates with metastasis and poor prognosis in patients with gastric cancer

(2019) Fei Wang et al.   JOURNAL OF SURGICAL ONCOLOGY

Tumor-associated Macrophages as Prognostic and Predictive Biomarkers for Postoperative Adjuvant Chemotherapy in Patients with Stage II Colon Cancer

(2019) Qingyang Feng et al.   CLINICAL CANCER RESEARCH

Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer‐associated fibroblasts

(2019) Ahmed E. Hegab et al.   JOURNAL OF PATHOLOGY

PRSS23 knockdown inhibits gastric tumorigenesis through EIF2 signaling

(2019) Bing Han et al.   PHARMACOLOGICAL RESEARCH

IRF6 Is Directly Regulated by ZEB1 and ELF3, and Predicts a Favorable Prognosis in Gastric Cancer

(2019) Dandan Li et al.   Frontiers in Oncology

LncRNA MAGI2-AS3 Is Regulated by BRD4 and Promotes Gastric Cancer Progression via Maintaining ZEB1 Overexpression by Sponging miR-141/200a

(2019) Dandan Li et al.   Molecular Therapy-Nucleic Acids

MicroRNA-155 inversely correlates with esophageal cancer progression through regulating tumor-associated macrophage FGF2 expression

(2018) Peng Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Knockout of Low Molecular Weight FGF2 Attenuates Atherosclerosis by Reducing Macrophage Infiltration and Oxidative Stress in Mice

(2018) Wenjing Liang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Acquired JHDM1D-BRAF fusion confers resistance to FGFR inhibition in FGFR2- amplified gastric cancer

(2018) Hitoshi Sase et al.   MOLECULAR CANCER THERAPEUTICS

PRSS8 suppresses colorectal carcinogenesis and metastasis

(2018) Yonghua Bao et al.   ONCOGENE

Honokiol induces apoptosis of lung squamous cell carcinoma by targeting FGF2-FGFR1 autocrine loop

(2018) Mengyuan Cen et al.   Cancer Medicine

LncRNA-MALAT1 Promotes Angiogenesis of Thyroid Cancer by Modulating Tumor-Associated Macrophage FGF2 Protein Secretion

(2017) Jian-kang Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β

(2017) Wen Min Lau et al.   MOLECULAR CANCER THERAPEUTICS

NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells

(2016) Nobuhisa Takase et al.   CANCER LETTERS

Cartilage degeneration is exacerbated by pro-inflammatory (M1) macrophages but not inhibited by anti-inflammatory (M2) macrophages in vitro

(2016) L. Utomo et al.   OSTEOARTHRITIS AND CARTILAGE

Overexpression of the Starch Phosphorylase-Like Gene (PHO3) in Lotus japonicus has a Profound Effect on the Growth of Plants and Reduction of Transitory Starch Accumulation

(2016) Shanshan Qin et al.   Frontiers in Plant Science

Second Primary Malignancies in Adults with Gastric Cancer – A US Population-Based Study

(2016) Binay Kumar Shah et al.   Frontiers in Oncology

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications

(2015) Teresa Helsten et al.   CANCER AND METASTASIS REVIEWS

Abstract 2044: Characterization of a novel tumor suppressor PRSS8 in colorectal cancer

(2015) Yonghua Bao et al.   CANCER RESEARCH

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes

(2015) Razvan Cristescu et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Much More than M1 and M2 Macrophages, There are also CD169+ and TCR+ Macrophages

(2015) Leslie Chávez-Galán et al.   Frontiers in Immunology

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

(2015) Ang Yuan et al.   Scientific Reports

Enhanced invasion of lung adenocarcinoma cells after co-culture with THP-1-derived macrophages via the induction of EMT by IL-6

(2014) Che Dehai et al.   IMMUNOLOGY LETTERS

1α,25(OH)2D3 inhibits FGF-2 release from oral squamous cell carcinoma cells through down-regulation of HBp17/FGFBP-1

(2014) S. N. Zawani B. Rosli et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Tumor-associated macrophages as potential diagnostic and prognostic biomarkers in breast cancer

(2013) Xiaoqiang Tang   CANCER LETTERS

Activation of the FGF2-FGFR1 Autocrine Pathway: A Novel Mechanism of Acquired Resistance to Gefitinib in NSCLC

(2013) Hideki Terai et al.   MOLECULAR CANCER RESEARCH

1α,25(OH)2D3 down-regulates HBp17/FGFBP-1 expression via NF-κB pathway

(2012) S.N.Z. Rosli et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY